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IID00465
UniprotQ12962
ProteinTranscription initiation factor TFIID subunit 10
GeneTAF10
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
218
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 112-212 Hetero dimer : Q7Z7C8
 Evidence X-RAY 4wv4 A Reference
       Region 4wv4 A 112-112 disorder
       Region 4wv4 A 113-177 order
       Region 4wv4 A 178-191 disorder
       Region 4wv4 A 192-212 order
Seq 186-195 Hetero dimer : IID00128Complex
 Evidence X-RAY 3m5a B Reference
       Region 3m5a B 186-193 order
       Region 3m5a B 194-195 disorder
 Evidence X-RAY 3m59 B Reference
       Region 3m59 B 186-193 order
       Region 3m59 B 194-195 disorder
 Evidence X-RAY 3m58 B Reference
       Region 3m58 B 186-193 order
       Region 3m58 B 194-195 disorder
 Evidence X-RAY 3m57 B Reference
       Region 3m57 B 186-193 order
       Region 3m57 B 194-195 disorder
 Evidence X-RAY 3m56 B Reference
       Region 3m56 B 186-191 order
       Region 3m56 B 192-195 disorder
 Evidence X-RAY 3m55 B Reference
       Region 3m55 B 186-192 order
       Region 3m55 B 193-195 disorder
 Evidence X-RAY 3m54 B Reference
       Region 3m54 B 186-193 order
       Region 3m54 B 194-195 disorder
 Evidence X-RAY 3m53 B Reference
       Region 3m53 B 186-193 order
       Region 3m53 B 194-195 disorder
 Evidence X-RAY 4j8o B Reference
       Region 4j8o B 186-192 order
       Region 4j8o B 193-195 disorder
 Evidence X-RAY 4j83 B Reference
       Region 4j83 B 186-191 order
       Region 4j83 B 192-195 disorder
 Evidence X-RAY 4j7i B Reference
       Region 4j7i B 186-191 order
       Region 4j7i B 192-195 disorder
 Evidence X-RAY 4j7f B Reference
       Region 4j7f B 186-191 order
       Region 4j7f B 192-195 disorder
 Evidence X-RAY 2f69 B Reference
       Region 2f69 B 186-193 order
       Region 2f69 B 194-195 disorder
 Evidence X-RAY 5eg2 B Reference
       Region 5eg2 B 186-191 order
       Region 5eg2 B 192-195 disorder
SeqProS verified 186-191 Hetero dimer : IID00128Complex
       Region 3m58 B 186-193 order
       Region 3m5a B 186-193 order
       Region 3m57 B 186-193 order
       Region 3m54 B 186-193 order
       Region 3m59 B 186-193 order
       Region 3m53 B 186-193 order
       Region 3m56 B 186-191 order
       Region 3m55 B 186-192 order
       Region 2f69 B 186-193 order
       Region 4j7i B 186-191 order
       Region 4j83 B 186-191 order
       Region 4j8o B 186-192 order
       Region 4j7f B 186-191 order
       Region 5eg2 B 186-191 order
       Region 4wv4 A 178-191 disorder
Seqphosphorylation
    48-48 Phosphothreonine
    44-44 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
 
Prediction
NeProc
Disorder 1-111,180-188
Order 112-179,189-218
AlphaFold
Disorder 2-5,7-24,26-114,178-190
Order 1-1,6-6,25-25,115-177,191-218
Pfam Hmmer
PF03540 128-178 4.1e-40
SEG 4-39 ,45-91 ,181-192
Function
Function in SwissProt
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.