IDEAL Node

IDEAL

IID00470 Nuclear factor of activated T-cells, cytoplasmic 2 (Homo sapiens) Q13469

:order :disorder :conflict :PDB cluster :ProS :SCOP Domain :Pfam Domain

Network xml

Experiment

925

fasta

order/disorder by at least rule

disorder by at least rule

order by at least rule

order/disorder by majority rule

Seq 392-678 Hetero trimer : IID00436Complex,IID00437Complex

Evidence X-RAY 1s9k C Reference

Region 1s9k C 399-678 order

Evidence X-RAY 1a02 N Reference

Region 1a02 N 392-398 disorder

Region 1a02 N 399-678 order

Seq 392-678 Hetero dimer : IID00429Complex

Evidence X-RAY 2as5 M Reference

Region 2as5 M 392-678 order

Evidence X-RAY 2as5 N Reference

Region 2as5 N 392-678 order

Seq 393-678 Homo dimer :

Evidence X-RAY 1pzu M Reference

Region 1pzu M 396-398 disorder

Region 1pzu M 399-571 order

Region 1pzu M 572-575 disorder

Region 1pzu M 576-678 order

Evidence X-RAY 1pzu L Reference

Region 1pzu L 396-398 disorder

Region 1pzu L 399-571 order

Region 1pzu L 572-575 disorder

Region 1pzu L 576-678 order

Evidence X-RAY 1pzu I Reference

Region 1pzu I 396-398 disorder

Region 1pzu I 399-571 order

Region 1pzu I 572-575 disorder

Region 1pzu I 576-678 order

Evidence X-RAY 1pzu H Reference

Region 1pzu H 396-398 disorder

Region 1pzu H 399-571 order

Region 1pzu H 572-575 disorder

Region 1pzu H 576-678 order

Evidence X-RAY 1pzu D Reference

Region 1pzu D 396-398 disorder

Region 1pzu D 399-571 order

Region 1pzu D 572-575 disorder

Region 1pzu D 576-678 order

Evidence X-RAY 1pzu B Reference

Region 1pzu B 396-398 disorder

Region 1pzu B 399-571 order

Region 1pzu B 572-575 disorder

Region 1pzu B 576-678 order

Evidence X-RAY 1p7h O Reference

Region 1p7h O 393-678 order

Evidence X-RAY 1p7h N Reference

Region 1p7h N 393-678 order

Evidence X-RAY 1p7h M Reference

Region 1p7h M 393-678 order

Evidence X-RAY 1p7h L Reference

Region 1p7h L 393-678 order

Seq 396-678 Hetero trimer : IID00497Complex

Evidence X-RAY 3qrf M Reference

Region 3qrf M 396-678 order

Evidence X-RAY 3qrf N Reference

Region 3qrf N 396-678 order

Seq 396-678 Monomer :

Evidence X-RAY 1owr Q Reference

Region 1owr Q 396-678 order

Evidence X-RAY 1owr P Reference

Region 1owr P 396-678 order

Evidence X-RAY 1owr N Reference

Region 1owr N 396-678 order

Evidence X-RAY 1owr M Reference

Region 1owr M 396-678 order

Seq 396-678 Homo trimer :

Evidence X-RAY 2o93 O Reference

Region 2o93 O 396-678 order

Evidence X-RAY 2o93 M Reference

Region 2o93 M 396-678 order

Evidence X-RAY 2o93 L Reference

Region 2o93 L 396-678 order

SeqProS possible 410-422,431-446,516-550

Same region of homolog (O95644, 84% identity) is disordered in the free state. This region binds to DNA. Homo dimer :

Region 1pzu B 399-571 order

Region 1pzu D 399-571 order

Region 1pzu H 399-571 order

Region 1pzu I 399-571 order

Region 1pzu L 399-571 order

Region 1pzu M 399-571 order

Region 1p7h L 393-678 order

Region 1p7h M 393-678 order

Region 1p7h N 393-678 order

Region 1p7h O 393-678 order

SeqProS possible 410-422,431-446,516-550

Same region of homolog (O95644, 84% identity) is disordered in the free state. This region binds to DNA. Hetero trimer : IID00497Complex

Region 3qrf M 396-678 order

Region 3qrf N 396-678 order

SeqProS possible 410-422,431-446,516-550

Same region of homolog (O95644, 84% identity) is disordered in the free state. This region binds to DNA. Homo trimer :

Region 2o93 L 396-678 order

Region 2o93 M 396-678 order

Region 2o93 O 396-678 order

SeqProS possible 410-422,431-446,516-550

Same region of homolog (O95644, 84% identity) is disordered in the free state. This region binds to DNA. Hetero dimer : IID00429Complex

Region 2as5 M 392-678 order

Region 2as5 N 392-678 order

SeqProS possible 410-422,431-446,516-550

Same region of homolog (O95644, 84% identity) is disordered in the free state. This region binds to DNA. Hetero trimer : IID00436Complex,IID00437Complex

Region 1a02 N 399-678 order

Region 1s9k C 399-678 order

SeqProS possible 410-422,431-446,516-550

Same region of homolog (O95644, 84% identity) is disordered in the free state. This region binds to DNA. :

Region 1owr M 396-678 order

Region 1owr N 396-678 order

Region 1owr P 396-678 order

Region 1owr Q 396-678 order

Seqphosphorylation

859-859 Phosphoserine

856-856 Phosphoserine

759-759 Phosphoserine

757-757 Phosphoserine

755-755 Phosphoserine

363-363 Phosphoserine

330-330 Phosphoserine

326-326 Phosphoserine

280-280 Phosphoserine

276-276 Phosphoserine

274-274 Phosphoserine

268-268 Phosphoserine

255-255 Phosphoserine

243-243 Phosphoserine

236-236 Phosphoserine

221-221 Phosphoserine

217-217 Phosphoserine

213-213 Phosphoserine

148-148 Phosphoserine

110-110 Phosphoserine

107-107 Phosphoserine

99-99 Phosphoserine

23-23 Phosphoserine

99-99 Phosphoserine

107-107 Phosphoserine

110-110 Phosphoserine

148-148 Phosphoserine

213-213 Phosphoserine

217-217 Phosphoserine

221-221 Phosphoserine

236-236 Phosphoserine

243-243 Phosphoserine

255-255 Phosphoserine

268-268 Phosphoserine

274-274 Phosphoserine

276-276 Phosphoserine

280-280 Phosphoserine

326-326 Phosphoserine

330-330 Phosphoserine

363-363 Phosphoserine

755-755 Phosphoserine

757-757 Phosphoserine

759-759 Phosphoserine

856-856 Phosphoserine

859-859 Phosphoserine

Prediction

DICHOT

Disorder 1-398,679-925

Known Domain 399-678

SCOPe RPS-Blast

2as5M2 396-575 9e-68

2as5M1 576-678 6e-28

SCOP Hmmer

1a02N2 399-575 5.4e-78

1a02N1 577-677 5.9e-35

Pfam RPS-Blast

PF00554 410-570 6e-39 Rel homology DNA-binding do...

PF16179 580-677 5e-23 Rel homology dimerisation d...

Pfam Hmmer

PF00554 410-570 7.5e-26 Rel homology DNA-binding d...

PF16179 580-677 3.7e-29 Rel homology dimerisation ...