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IID00508  Eukaryotic translation initiation factor 2 subunit 1 (Homo sapiens) P05198  LLPSCytoplasm, Stress granule.
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
xml
Experiment
315
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-183 Monomer :
 Evidence X-RAY 1kl9 A Reference
       Region 1kl9 A 2-3 disorder
       Region 1kl9 A 4-51 order
       Region 1kl9 A 52-63 disorder
       Region 1kl9 A 64-183 order
Seq 5-303 Monomer :
 Evidence NMR 1q8k A Reference
       Region 1q8k A 5-303 order
Seqphosphorylation
    49-49 Phosphoserine; by HRI
    52-52 Phosphoserine
    158-158 Phosphoserine
    279-279 Phosphothreonine
    281-281 Phosphothreonine
Seqacetylation
    141-141 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-3,296-315
Known Domain 4-295
SCOPe RPS-Blast
     1kl9A2 4-89 1e-30 b.40.4.5 Archaeal initiation factor-1a, aIF1a
     1kl9A1 90-183 1e-29 a.60.14.1 Eukaryotic initiation factor 2alpha, ...
     1q8kA2 187-303 6e-36 d.58.51.1 eIF-2-alpha, C-terminal domain
SCOP Hmmer
     1luzA_ 11-93 3.2e-20 b.40.4.5 Archaeal initiati...
     1kl9A1 90-183 1.6e-35 a.60.14.1 Eukaryotic init...
     1q8kA2 187-303 1.5e-44 d.58.51.1 eIF-2-alpha, C...
Pfam RPS-Blast
     PF07541 130-243 1e-34 Eukaryotic translation init...
Pfam Hmmer
    PF00575 14-88 3e-19 S1 RNA binding domain
    PF07541 131-243 1.5e-40 Eukaryotic translation ini...