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IID00518
 UniprotQ92990
ProteinGlomulin
GeneGLMN
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
594
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-594 Hetero trimer : IID00059Complex,IID00133Complex
 Evidence X-RAY 4f52 E Reference
       Region 4f52 E 1-17 order
       Region 4f52 E 18-26 disorder
       Region 4f52 E 27-163 order
       Region 4f52 E 164-167 disorder
       Region 4f52 E 168-226 order
       Region 4f52 E 227-234 disorder
       Region 4f52 E 235-258 order
       Region 4f52 E 259-279 disorder
       Region 4f52 E 280-434 order
       Region 4f52 E 435-438 disorder
       Region 4f52 E 439-535 order
       Region 4f52 E 536-549 disorder
       Region 4f52 E 550-583 order
       Region 4f52 E 584-594 disorder
 Evidence X-RAY 4f52 F Reference
       Region 4f52 F 1-19 order
       Region 4f52 F 20-21 disorder
       Region 4f52 F 22-39 order
       Region 4f52 F 40-44 disorder
       Region 4f52 F 45-75 order
       Region 4f52 F 76-80 disorder
       Region 4f52 F 81-161 order
       Region 4f52 F 162-164 disorder
       Region 4f52 F 165-193 order
       Region 4f52 F 194-200 disorder
       Region 4f52 F 201-226 order
       Region 4f52 F 227-233 disorder
       Region 4f52 F 234-259 order
       Region 4f52 F 260-278 disorder
       Region 4f52 F 279-432 order
       Region 4f52 F 433-438 disorder
       Region 4f52 F 439-532 order
       Region 4f52 F 533-549 disorder
       Region 4f52 F 550-583 order
       Region 4f52 F 584-594 disorder
Seqacetylation
    2-2 N-acetylalanine
 
Prediction
NeProc
Disorder 1-4,533-545,584-594
Order 5-532,546-583
ProS 533-545,589-594
AlphaFold
Disorder 77-78,195-197,228-233,253-253,261-280,435-437,530-549,585-594
Order 1-76,79-194,198-227,234-252,254-260,281-434,438-529,550-584
SEG 101-112 ,117-130 ,193-210
Function
Function in SwissProt
Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. Isoform 1 may stimulate the p70S6K pathway. Isoform 2 may inhibit cell proliferation and increase IL2 production.