Search Keyword:


Search option:


IID00526  Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens) O15111
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
745
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 10-660 Homo hexamer :
 Evidence X-RAY 5ebz A Reference
       Region 5ebz A 10-660 order
 Evidence X-RAY 5ebz B Reference
       Region 5ebz B 10-660 order
 Evidence X-RAY 5ebz C Reference
       Region 5ebz C 10-660 order
 Evidence X-RAY 5ebz D Reference
       Region 5ebz D 10-660 order
 Evidence X-RAY 5ebz E Reference
       Region 5ebz E 10-660 order
 Evidence X-RAY 5ebz F Reference
       Region 5ebz F 10-660 order
 Evidence X-RAY 5ebz G Reference
       Region 5ebz G 10-660 order
 Evidence X-RAY 5ebz H Reference
       Region 5ebz H 10-660 order
 Evidence X-RAY 5ebz I Reference
       Region 5ebz I 10-660 order
 Evidence X-RAY 5ebz J Reference
       Region 5ebz J 10-660 order
 Evidence X-RAY 5ebz K Reference
       Region 5ebz K 10-660 order
 Evidence X-RAY 5ebz L Reference
       Region 5ebz L 10-660 order
Seq 732-745 Hetero trimer : IID00525Complex,Q9Y6K9
 Evidence X-RAY 3brt C Reference
       Region 3brt C 732-744 order
       Region 3brt C 745-745 disorder
Seq 732-745 Hetero trimer : IID00525Complex,Q9Y6K9
 Evidence X-RAY 3brt A Reference
       Region 3brt A 732-744 order
       Region 3brt A 745-745 disorder
Seq 732-745 Hetero trimer : IID00525Complex,Q9Y6K9
 Evidence X-RAY 3brt A Reference
       Region 3brt A 732-744 order
       Region 3brt A 745-745 disorder
Seq 732-745 Hetero trimer : IID00525Complex,Q9Y6K9
 Evidence X-RAY 3brt C Reference
       Region 3brt C 732-744 order
       Region 3brt C 745-745 disorder
Seqphosphorylation
    23-23 Phosphothreonine; by PKB/AKT1 and SGK1
    176-176 Phosphoserine; by MAP3K14
    180-180 Phosphoserine; by SGK1
Seqacetylation
    179-179 O-acetylthreonine; by Yersinia yopJ
 
Prediction
DICHOT
Disorder 1-14,660-745
Known Domain 15-659
SCOPe RPS-Blast
     4wnoA 13-287 6e-48 d.144.1.0 automated matches
SCOP Hmmer
     1omwA3 13-297 1.5e-67 d.144.1.7 3-phosphoinosit...
Pfam RPS-Blast
     PF06293 57-153 3e-04 Lipopolysaccharide kinase (K...
     PF18397 386-659 e-110 IQBAL scaffold dimerization...
     PF12179 707-743 2e-12 I-kappa-kinase-beta NEMO bi...
Pfam Hmmer
    PF00069 17-289 1.3e-57 Protein kinase domain
    PF18397 386-659 6.2e-138 IQBAL scaffold dimerizati...
    PF12179 707-743 7.4e-21 I-kappa-kinase-beta NEMO b...