Search Keyword:


Search option:


IID00553  Tyrosine-protein kinase ZAP-70 (Homo sapiens) P43403
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
619
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-259 Hetero dimer : IID00544Complex
 Evidence X-RAY 2oq1 A Reference
       Region 2oq1 A 3-256 order
 Evidence X-RAY 4xz1 A Reference
       Region 4xz1 A 1-2 disorder
       Region 4xz1 A 3-256 order
       Region 4xz1 A 257-259 disorder
Seq 1-259 Monomer :
 Evidence X-RAY 1m61 A Reference
       Region 1m61 A 1-256 order
 Evidence X-RAY 4xz0 A Reference
       Region 4xz0 A 1-257 order
       Region 4xz0 A 258-259 disorder
Seq 1-606 Monomer :
 Evidence X-RAY 4k2r A Reference
       Region 4k2r A 1-1 disorder
       Region 4k2r A 2-257 order
       Region 4k2r A 258-302 disorder
       Region 4k2r A 303-483 order
       Region 4k2r A 484-500 disorder
       Region 4k2r A 501-606 order
 Evidence X-RAY 2ozo A Reference
       Region 2ozo A 1-1 disorder
       Region 2ozo A 2-256 order
       Region 2ozo A 257-309 disorder
       Region 2ozo A 310-487 order
       Region 2ozo A 488-501 disorder
       Region 2ozo A 502-606 order
Seq 286-297 Hetero hexamer : IID00300Complex
 Evidence X-RAY 2cbl B Reference
       Region 2cbl B 286-288 disorder
       Region 2cbl B 289-297 order
Seq 286-297 Hetero trimer : IID00300Complex
 Evidence X-RAY 5o76 D Reference
       Region 5o76 D 286-288 disorder
       Region 5o76 D 289-297 order
Seq 286-297 Hetero tetramer : IID00319Complex
 Evidence X-RAY 3zni B Reference
       Region 3zni B 286-288 disorder
       Region 3zni B 289-297 order
 Evidence X-RAY 3zni F Reference
       Region 3zni F 286-289 disorder
       Region 3zni F 290-297 order
 Evidence X-RAY 3zni J Reference
       Region 3zni J 286-289 disorder
       Region 3zni J 290-297 order
 Evidence X-RAY 3zni N Reference
       Region 3zni N 286-288 disorder
       Region 3zni N 289-297 order
Seq 286-297 Hetero trimer : IID00300Complex
 Evidence X-RAY 5o76 B Reference
       Region 5o76 B 286-289 disorder
       Region 5o76 B 290-296 order
       Region 5o76 B 297-297 disorder
Seq 286-297 Hetero trimer : IID00300Complex
 Evidence X-RAY 4a4b B Reference
       Region 4a4b B 286-288 disorder
       Region 4a4b B 289-297 order
 Evidence X-RAY 4a4c B Reference
       Region 4a4c B 286-288 disorder
       Region 4a4c B 289-297 order
Seq 286-297 Hetero dimer : IID00300Complex
 Evidence X-RAY 2y1n D Reference
       Region 2y1n D 286-288 disorder
       Region 2y1n D 289-297 order
 Evidence X-RAY 2y1n B Reference
       Region 2y1n B 286-288 disorder
       Region 2y1n B 289-297 order
Seq 289-297 Hetero trimer : IID00300Complex
 Evidence X-RAY 1fbv B Reference
       Region 1fbv B 289-297 order
Seq 327-606 Monomer :
 Evidence X-RAY 1u59 A Reference
       Region 1u59 A 327-327 disorder
       Region 1u59 A 328-358 order
       Region 1u59 A 359-361 disorder
       Region 1u59 A 362-606 order
SeqProS verified 289-297 Hetero trimer : IID00300Complex
       Region 4a4b B 289-297 order
       Region 4a4c B 289-297 order
       Region 2ozo A 257-309 disorder
SeqProS verified 289-297 Hetero dimer : IID00300Complex
       Region 2y1n B 289-297 order
       Region 2y1n D 289-297 order
       Region 2ozo A 257-309 disorder
SeqProS verified 289-297 Hetero hexamer : IID00300Complex
       Region 2cbl B 289-297 order
       Region 2ozo A 257-309 disorder
SeqProS verified 289-297 Hetero tetramer : IID00319Complex
       Region 3zni B 289-297 order
       Region 3zni F 290-297 order
       Region 3zni J 290-297 order
       Region 3zni N 289-297 order
       Region 2ozo A 257-309 disorder
SeqProS verified 289-297 Hetero trimer : IID00300Complex
       Region 5o76 D 289-297 order
       Region 2ozo A 257-309 disorder
SeqProS verified 289-297 Hetero trimer : IID00300Complex
       Region 1fbv B 289-297 order
       Region 2ozo A 257-309 disorder
SeqProS verified 290-296 Hetero trimer : IID00300Complex
       Region 5o76 B 290-296 order
       Region 2ozo A 257-309 disorder
Seqphosphorylation
    248-248 Phosphotyrosine
    289-289 Phosphoserine
    292-292 Phosphotyrosine
    315-315 Phosphotyrosine; by LCK
    319-319 Phosphotyrosine
    492-492 Phosphotyrosine
    493-493 Phosphotyrosine
Seqacetylation
    603-603 N6-acetyllysine
 
Prediction
DICHOT
Disorder 1-1,607-619
Known Domain 2-606
SCOPe RPS-Blast
     2oq1A1 3-132 5e-44 d.93.1.1 Abl tyrosine kinase
     2oq1A2 133-256 3e-45 d.93.1.1 Abl tyrosine kinase
     4fyoA1 330-602 e-117 d.144.1.7 3-phosphoinositide dependent protein...
SCOP Hmmer
     1a81A1 7-132 1.8e-30 d.93.1.1 Abl tyrosine kina...
     1m61A2 143-255 1.1e-31 d.93.1.1 Abl tyrosine ki...
     1m14A_ 343-599 1.1e-73 d.144.1.7 3-phosphoinosi...
Pfam RPS-Blast
     PF00017 163-238 2e-05 SH2 domain
     PF06293 384-493 9e-07 Lipopolysaccharide kinase (...
Pfam Hmmer
    PF00017 10-87 1.4e-20 SH2 domain
    PF00017 163-238 4.4e-24 SH2 domain
    PF07714 342-591 1.9e-93 Protein tyrosine kinase