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IID00603  G1/S-specific cyclin-E1 (Homo sapiens) P24864
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
410
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 96-378 Hetero dimer : IID00034Complex
 Evidence X-RAY 1w98 B Reference
       Region 1w98 B 96-102 disorder
       Region 1w98 B 103-372 order
       Region 1w98 B 373-378 disorder
 Evidence X-RAY 5l2w B Reference
       Region 5l2w B 96-102 disorder
       Region 5l2w B 103-372 order
       Region 5l2w B 373-378 disorder
Seqphosphorylation
    77-77 Phosphothreonine
    103-103 Phosphoserine
    387-387 Phosphoserine
    395-395 Phosphothreonine; by GSK3
    399-399 Phosphoserine; by CDK2
 
Prediction
DICHOT
Disorder 1-102,373-410
Known Domain 103-372
SCOPe RPS-Blast
     1w98B2 103-242 2e-61 a.74.1.1 CDK5 activator 1 (NCK5a, p25)
     1w98B1 243-372 3e-50 a.74.1.1 CDK5 activator 1 (NCK5a, p25)
SCOP Hmmer
     1w98B2 108-241 9.4e-47 a.74.1.1 CDK5 activator ...
     1w98B1 243-372 2.1e-53 a.74.1.1 CDK5 activator ...
Pfam Hmmer
    PF00134 115-242 1.7e-45 Cyclin, N-terminal domain
    PF02984 245-365 1.2e-23 Cyclin, C-terminal domain