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IID00606  Rho guanine nucleotide exchange factor 4 (Homo sapiens) Q9NR80
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
690
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 143-632 Monomer :
 Evidence X-RAY 2dx1 A Reference
       Region 2dx1 A 143-184 disorder
       Region 2dx1 A 185-255 order
       Region 2dx1 A 256-276 disorder
       Region 2dx1 A 277-555 order
       Region 2dx1 A 556-568 disorder
       Region 2dx1 A 569-576 order
       Region 2dx1 A 577-582 disorder
       Region 2dx1 A 583-609 order
       Region 2dx1 A 610-611 disorder
 Evidence X-RAY 2pz1 A Reference
       Region 2pz1 A 170-180 disorder
       Region 2pz1 A 181-254 order
       Region 2pz1 A 255-277 disorder
       Region 2pz1 A 278-611 order
       Region 2pz1 A 612-632 disorder
Seq 170-194 Hetero dimer : IID00035Complex
 Evidence X-RAY 3nmx D Reference
       Region 3nmx D 170-179 disorder
       Region 3nmx D 180-192 order
       Region 3nmx D 193-194 disorder
 Evidence X-RAY 3nmx E Reference
       Region 3nmx E 170-179 disorder
       Region 3nmx E 180-192 order
       Region 3nmx E 193-194 disorder
 Evidence X-RAY 3nmx F Reference
       Region 3nmx F 170-179 disorder
       Region 3nmx F 180-192 order
       Region 3nmx F 193-194 disorder
Seq 170-276 Hetero dimer : IID00035Complex
 Evidence X-RAY 3nmz C Reference
       Region 3nmz C 170-170 disorder
       Region 3nmz C 171-255 order
       Region 3nmz C 256-276 disorder
 Evidence X-RAY 3nmz D Reference
       Region 3nmz D 170-171 disorder
       Region 3nmz D 172-255 order
       Region 3nmz D 256-276 disorder
 
Prediction
DICHOT
Disorder 1-184,610-690
Known Domain 185-609
SCOPe RPS-Blast
     4a63B2 191-250 1e-15 b.34.2.0 automated matches
     2dfkA1 279-473 2e-94 a.87.1.1 beta-pix
     2dfkA2 474-634 3e-52 b.55.1.1 3-phosphoinositide dependent protein ...
SCOP Hmmer
     1vyvA1 182-300 4.4e-24 b.34.2.1 53BP2
     1txdA1 276-489 2.5e-62 a.87.1.1 beta-pix
     2dfkA2 474-630 6.6e-49 b.55.1.1 3-phosphoinosit...
Pfam RPS-Blast
     PF14604 201-244 2e-07 Variant SH3 domain
Pfam Hmmer
    PF00018 201-245 6.4e-14 SH3 domain
    PF00621 288-466 5.9e-50 RhoGEF domain
    PF00169 501-601 7e-12 PH domain