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IID00619  KH domain-containing, RNA-binding, signal transduction-associated protein 1 (Homo sapiens) Q07666
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
443
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 97-135 Homo dimer :
 Evidence NMR 2xa6 A Reference
       Region 2xa6 A 97-98 disorder
       Region 2xa6 A 99-135 order
 Evidence NMR 2xa6 B Reference
       Region 2xa6 B 97-98 disorder
       Region 2xa6 B 99-135 order
Seq 365-419 Hetero dimer : IID00035Complex
 Evidence X-RAY 3qhe B Reference
       Region 3qhe B 365-378 disorder
       Region 3qhe B 379-388 order
       Region 3qhe B 389-419 disorder
 Evidence X-RAY 3qhe D Reference
       Region 3qhe D 365-378 disorder
       Region 3qhe D 379-389 order
       Region 3qhe D 390-419 disorder
SeqProS possible 379-389 This region is described to be disordered in the free state (PubMed=22000517). Hetero dimer : IID00035Complex
       Region 3qhe B 379-388 order
       Region 3qhe D 379-389 order
Seqphosphorylation
    18-18 Phosphoserine
    20-20 Phosphoserine
    29-29 Phosphoserine
    33-33 Phosphothreonine
    58-58 Phosphoserine
    84-84 Phosphothreonine; by MAPK1
    113-113 Phosphoserine
    150-150 Phosphoserine
    183-183 Phosphothreonine
    387-387 Phosphotyrosine
    390-390 Phosphoserine
    435-435 Phosphotyrosine; by PTK6
    440-440 Phosphotyrosine; by PTK6
    443-443 Phosphotyrosine; by PTK6
Seqacetylation
    175-175 N6-acetyllysine; alternate
 
Prediction
DICHOT
Disorder 1-95,276-443
Known Domain 96-275
SCOPe RPS-Blast
     1k1gA 155-276 4e-28 d.51.1.1 Exosome complex RNA-binding protein 1, ...
SCOP Hmmer
     2bl5A1 156-276 3.2e-32 d.51.1.1 Exosome complex...
Pfam RPS-Blast
     PF16274 102-153 1e-18 Qua1 domain
     PF16568 366-415 7e-16 Tyrosine-rich domain of Sam...
Pfam Hmmer
    PF16274 102-153 3e-36 Qua1 domain
    PF00013 158-213 1.3e-14 KH domain
    PF16568 366-415 7.3e-19 Tyrosine-rich domain of Sa...