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IID00632
 UniprotQ9Y5L0
ProteinTransportin-3
GeneTNPO3
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
923
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-923 Hetero dimer : Q07955
 Evidence X-RAY 4c0o A Reference
       Region 4c0o A 1-2 disorder
       Region 4c0o A 3-598 order
       Region 4c0o A 599-604 disorder
       Region 4c0o A 605-626 order
       Region 4c0o A 627-631 disorder
       Region 4c0o A 632-880 order
       Region 4c0o A 881-888 disorder
       Region 4c0o A 889-922 order
       Region 4c0o A 923-923 disorder
 Evidence X-RAY 4c0o B Reference
       Region 4c0o B 1-2 disorder
       Region 4c0o B 3-189 order
       Region 4c0o B 190-192 disorder
       Region 4c0o B 193-598 order
       Region 4c0o B 599-604 disorder
       Region 4c0o B 605-626 order
       Region 4c0o B 627-631 disorder
       Region 4c0o B 632-880 order
       Region 4c0o B 881-888 disorder
       Region 4c0o B 889-922 order
       Region 4c0o B 923-923 disorder
Seq 1-923 Monomer :
 Evidence X-RAY 4c0p A Reference
       Region 4c0p A 1-2 disorder
       Region 4c0p A 3-189 order
       Region 4c0p A 190-194 disorder
       Region 4c0p A 195-429 order
       Region 4c0p A 430-431 disorder
       Region 4c0p A 432-595 order
       Region 4c0p A 596-606 disorder
       Region 4c0p A 607-626 order
       Region 4c0p A 627-631 disorder
       Region 4c0p A 632-880 order
       Region 4c0p A 881-888 disorder
       Region 4c0p A 889-922 order
       Region 4c0p A 923-923 disorder
 Evidence X-RAY 4c0p B Reference
       Region 4c0p B 1-2 disorder
       Region 4c0p B 3-189 order
       Region 4c0p B 190-194 disorder
       Region 4c0p B 195-429 order
       Region 4c0p B 430-431 disorder
       Region 4c0p B 432-595 order
       Region 4c0p B 596-606 disorder
       Region 4c0p B 607-626 order
       Region 4c0p B 627-631 disorder
       Region 4c0p B 632-880 order
       Region 4c0p B 881-888 disorder
       Region 4c0p B 889-922 order
       Region 4c0p B 923-923 disorder
 Evidence X-RAY 4c0p C Reference
       Region 4c0p C 1-2 disorder
       Region 4c0p C 3-189 order
       Region 4c0p C 190-194 disorder
       Region 4c0p C 195-429 order
       Region 4c0p C 430-431 disorder
       Region 4c0p C 432-595 order
       Region 4c0p C 596-606 disorder
       Region 4c0p C 607-626 order
       Region 4c0p C 627-631 disorder
       Region 4c0p C 632-880 order
       Region 4c0p C 881-888 disorder
       Region 4c0p C 889-922 order
       Region 4c0p C 923-923 disorder
 Evidence X-RAY 4c0p D Reference
       Region 4c0p D 1-2 disorder
       Region 4c0p D 3-189 order
       Region 4c0p D 190-194 disorder
       Region 4c0p D 195-429 order
       Region 4c0p D 430-431 disorder
       Region 4c0p D 432-595 order
       Region 4c0p D 596-606 disorder
       Region 4c0p D 607-626 order
       Region 4c0p D 627-631 disorder
       Region 4c0p D 632-881 order
       Region 4c0p D 882-888 disorder
       Region 4c0p D 889-922 order
       Region 4c0p D 923-923 disorder
Seq 1-923 Hetero dimer : IID00162Complex
 Evidence X-RAY 4c0q A Reference
       Region 4c0q A 1-4 disorder
       Region 4c0q A 5-189 order
       Region 4c0q A 190-194 disorder
       Region 4c0q A 195-353 order
       Region 4c0q A 354-362 disorder
       Region 4c0q A 363-595 order
       Region 4c0q A 596-606 disorder
       Region 4c0q A 607-624 order
       Region 4c0q A 625-633 disorder
       Region 4c0q A 634-671 order
       Region 4c0q A 672-676 disorder
       Region 4c0q A 677-880 order
       Region 4c0q A 881-888 disorder
       Region 4c0q A 889-922 order
       Region 4c0q A 923-923 disorder
 Evidence X-RAY 4c0q B Reference
       Region 4c0q B 1-4 disorder
       Region 4c0q B 5-54 order
       Region 4c0q B 55-56 disorder
       Region 4c0q B 57-158 order
       Region 4c0q B 159-165 disorder
       Region 4c0q B 166-187 order
       Region 4c0q B 188-195 disorder
       Region 4c0q B 196-355 order
       Region 4c0q B 356-358 disorder
       Region 4c0q B 359-447 order
       Region 4c0q B 448-457 disorder
       Region 4c0q B 458-488 order
       Region 4c0q B 489-494 disorder
       Region 4c0q B 495-526 order
       Region 4c0q B 527-551 disorder
       Region 4c0q B 552-560 order
       Region 4c0q B 561-580 disorder
       Region 4c0q B 581-594 order
       Region 4c0q B 595-606 disorder
       Region 4c0q B 607-621 order
       Region 4c0q B 622-641 disorder
       Region 4c0q B 642-671 order
       Region 4c0q B 672-682 disorder
       Region 4c0q B 683-705 order
       Region 4c0q B 706-721 disorder
       Region 4c0q B 722-765 order
       Region 4c0q B 766-771 disorder
       Region 4c0q B 772-810 order
       Region 4c0q B 811-818 disorder
       Region 4c0q B 819-877 order
       Region 4c0q B 878-892 disorder
       Region 4c0q B 893-922 order
       Region 4c0q B 923-923 disorder
 Evidence X-RAY 4ol0 B Reference
       Region 4ol0 B 3-3 disorder
       Region 4ol0 B 4-215 order
       Region 4ol0 B 216-220 disorder
       Region 4ol0 B 221-597 order
       Region 4ol0 B 598-605 disorder
       Region 4ol0 B 606-883 order
       Region 4ol0 B 884-888 disorder
       Region 4ol0 B 889-923 order
Seqphosphorylation
    74-74 Phosphoserine
    896-896 Phosphothreonine
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
NeProc
Disorder 1-6
Order 7-599,605-923
AlphaFold
Disorder 1-3,600-605
Order 4-599,606-923
Pfam Hmmer
PF08389 101-249 4.5e-43
SEG 108-117 ,318-328
Function
Function in SwissProt
Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains.