IDEAL Node

IDEAL

IID00646 Low-density lipoprotein receptor (Homo sapiens) P01130

:order :disorder :conflict :PDB cluster :ProS :SCOP Domain :Pfam Domain

Network xml

Experiment

860

fasta

order/disorder by at least rule

disorder by at least rule

order by at least rule

order/disorder by majority rule

Seq 4-788 Hetero trimer : Q8NBP7

Evidence X-RAY 3m0c C Reference

Region 3m0c C 4-275 disorder

Region 3m0c C 276-456 order

Region 3m0c C 457-464 disorder

Region 3m0c C 465-713 order

Region 3m0c C 714-788 disorder

Seq 20-67 Monomer :

Evidence NMR 1ldl A Reference

Region 1ldl A 20-21 disorder

Region 1ldl A 22-67 order

Region 1ldl A 22-26 high_rmsd

Region 1ldl A 66-67 high_rmsd

Seq 22-104 Monomer :

Evidence NMR 1f5y A Reference

Region 1f5y A 22-104 order

Seq 22-720 Monomer :

Evidence X-RAY 1n7d A Reference

Region 1n7d A 22-64 disorder

Region 1n7d A 65-77 order

Region 1n7d A 78-79 disorder

Region 1n7d A 80-95 order

Region 1n7d A 96-96 disorder

Region 1n7d A 97-119 order

Region 1n7d A 120-123 disorder

Region 1n7d A 124-408 order

Region 1n7d A 409-409 disorder

Region 1n7d A 410-461 order

Region 1n7d A 462-462 disorder

Region 1n7d A 463-473 order

Region 1n7d A 474-475 disorder

Region 1n7d A 476-714 order

Region 1n7d A 715-720 disorder

Seq 64-104 Monomer :

Evidence NMR 1ldr A Reference

Region 1ldr A 64-104 order

Region 1ldr A 64-67 high_rmsd

Seq 82-104 Monomer : IID00681Complex

Evidence NMR 2m7p A Reference

Region 2m7p A 82-104 order

Seq 107-186 Hetero dimer : P30533

Evidence X-RAY 2fcw B Reference

Region 2fcw B 107-184 order

Region 2fcw B 185-186 disorder

Seq 144-235 Monomer :

Evidence NMR 2lgp A Reference

Region 2lgp A 144-235 order

Seq 147-186 Hetero dimer : IID00647Complex

Evidence NMR 2kri B Reference

Region 2kri B 147-184 order

Region 2kri B 185-186 disorder

Seq 196-232 Monomer :

Evidence X-RAY 1ajj A Reference

Region 1ajj A 196-232 order

Seq 233-272 Monomer :

Evidence NMR 1f8z A Reference

Region 1f8z A 234-272 order

Evidence NMR 1d2j A Reference

Region 1d2j A 233-272 order

Seq 272-353 Monomer :

Evidence NMR 1xfe A Reference

Region 1xfe A 272-353 order

Region 1xfe A 272-275 high_rmsd

Seq 276-715 Hetero trimer : Q8NBP7

Evidence X-RAY 3p5c L Reference

Region 3p5c L 276-715 order

Evidence X-RAY 3p5b L Reference

Region 3p5b L 316-456 order

Region 3p5b L 457-462 disorder

Region 3p5b L 463-715 order

Seq 314-339 Hetero trimer : Q8NBP7

Evidence X-RAY 4ne9 D Reference

Region 4ne9 D 314-339 order

Seq 314-339 Monomer :

Evidence NMR 2mg9 A Reference

Region 2mg9 A 314-339 order

Seq 314-393 Hetero trimer : Q8NBP7

Evidence X-RAY 2w2q E Reference

Region 2w2q E 314-353 order

Region 2w2q E 354-393 disorder

Evidence X-RAY 2w2p E Reference

Region 2w2p E 314-353 order

Region 2w2p E 354-393 disorder

Evidence X-RAY 2w2o E Reference

Region 2w2o E 314-353 order

Region 2w2o E 354-393 disorder

Evidence X-RAY 2w2n E Reference

Region 2w2n E 314-354 order

Region 2w2n E 355-393 disorder

Evidence X-RAY 2w2m E Reference

Region 2w2m E 314-354 order

Region 2w2m E 355-393 disorder

Seq 314-393 Hetero trimer : Q8NBP7

Evidence X-RAY 3gcx E Reference

Region 3gcx E 314-353 order

Region 3gcx E 354-393 disorder

Evidence X-RAY 3gcw E Reference

Region 3gcw E 314-353 order

Region 3gcw E 354-393 disorder

Evidence X-RAY 3bps E Reference

Region 3bps E 314-353 order

Region 3bps E 354-393 disorder

Seq 314-395 Monomer :

Evidence NMR 1i0u A Reference

Region 1i0u A 314-395 order

Evidence NMR 1hz8 A Reference

Region 1hz8 A 314-395 order

Region 1hz8 A 314-316 high_rmsd

Region 1hz8 A 381-395 high_rmsd

Evidence NMR 1hj7 A Reference

Region 1hj7 A 314-393 order

Region 1hj7 A 314-314 high_rmsd

Seq 398-713 Monomer :

Evidence X-RAY 1ijq B Reference

Region 1ijq B 398-414 order

Region 1ijq B 415-416 disorder

Region 1ijq B 417-455 order

Region 1ijq B 456-464 disorder

Region 1ijq B 465-713 order

Evidence X-RAY 1ijq A Reference

Region 1ijq A 398-456 order

Region 1ijq A 457-464 disorder

Region 1ijq A 465-713 order

Seq 819-832 Hetero dimer : IID50263Complex

Evidence X-RAY 3so6 Q Reference

Region 3so6 Q 819-819 disorder

Region 3so6 Q 820-832 order

Seqphosphorylation

724-724 Phosphothreonine

Prediction

DICHOT

Disorder 1-26,713-860

Known Domain 27-712

SCOPe RPS-Blast

2gtlM2 26-63 3e-08

1v9u5 68-104 6e-10

2fcwB1 107-145 9e-13

1j8eA 147-185 6e-08

2fcwB1 197-233 9e-10

2fcwB1 235-270 2e-09

1xfeA2 272-314 6e-13

2w2nE1 314-354 5e-15

1uzkA1 354-392 2e-08

1ijqA1 398-663 e-113

1ijqA2 664-713 5e-14

SCOP Hmmer

1n7dA7 26-70 3.3e-12

1f5yA2 66-104 1.1e-11

1jrfA_ 103-144 4.7e-13 LDL receptor-like modul...

1jrfA_ 142-183 9.1e-13 LDL receptor-like modul...

1ldlA_ 196-232 5.7e-12

1n7dAa 234-272 2.1e-11

2dtgE6 282-394 1.4e-12

1ijqA1 398-661 7.7e-51

1ijqA2 664-712 1.4e-08

Pfam RPS-Blast

PF00057 27-58 4e-06 Low-density lipoprotein recep...

PF00057 68-104 9e-05 Low-density lipoprotein rece...

PF00057 109-143 2e-07 Low-density lipoprotein rec...

PF00057 148-179 2e-05 Low-density lipoprotein rec...

PF00057 197-231 2e-07 Low-density lipoprotein rec...

PF00057 236-270 1e-06 Low-density lipoprotein rec...

PF00057 279-308 5e-04 Low-density lipoprotein rec...

PF14670 364-392 9e-04 Coagulation Factor Xa inhib...

PF00058 439-483 2e-06 Low-density lipoprotein rec...

PF00058 487-526 4e-07 Low-density lipoprotein rec...

PF00058 529-569 2e-11 Low-density lipoprotein rec...

PF00058 573-614 2e-07 Low-density lipoprotein rec...

Pfam Hmmer

PF00057 26-63 1.5e-16 Low-density lipoprotein rece...

PF00057 67-104 1.9e-15 Low-density lipoprotein rec...

PF00057 107-143 3.2e-16 Low-density lipoprotein re...

PF00057 147-184 1.7e-17 Low-density lipoprotein re...

PF00057 196-231 6.6e-18 Low-density lipoprotein re...

PF00057 235-270 1e-15 Low-density lipoprotein rece...

PF00057 276-313 3.8e-15 Low-density lipoprotein re...

PF14670 318-348 8.3e-12 Coagulation Factor Xa inhi...

PF07645 354-392 2.1e-11 Calcium-binding EGF domain

PF00058 439-483 1.3e-16 Low-density lipoprotein re...

PF00058 487-526 1.4e-16 Low-density lipoprotein re...

PF00058 529-569 1.6e-17 Low-density lipoprotein re...

PF00058 573-614 4.6e-16 Low-density lipoprotein re...

PF00058 616-656 8.2e-10 Low-density lipoprotein re...

PF14670 673-711 3.7e-13 Coagulation Factor Xa inhi...