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IID00669  Beclin-1 (Homo sapiens) Q14457
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
450
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 105-130 Hetero dimer : P89884
 Evidence X-RAY 3dvu C Reference
       Region 3dvu C 105-105 disorder
       Region 3dvu C 106-129 order
       Region 3dvu C 130-130 disorder
 Evidence X-RAY 3dvu D Reference
       Region 3dvu D 105-128 order
       Region 3dvu D 129-130 disorder
 Evidence X-RAY 4mi8 C Reference
       Region 4mi8 C 107-107 disorder
       Region 4mi8 C 108-127 order
       Region 4mi8 C 128-130 disorder
 Evidence X-RAY 4mi8 D Reference
       Region 4mi8 D 107-127 order
       Region 4mi8 D 128-130 disorder
Seqdisorder 105-140
 Evidence CD Reference
       Region 105-140 disorder
Seq 106-135 Hetero dimer : Q07817
 Evidence X-RAY 2p1l B Reference
       Region 2p1l B 107-128 order
       Region 2p1l B 129-135 disorder
 Evidence X-RAY 2p1l D Reference
       Region 2p1l D 107-128 order
       Region 2p1l D 129-135 disorder
 Evidence X-RAY 2p1l F Reference
       Region 2p1l F 107-128 order
       Region 2p1l F 129-135 disorder
 Evidence X-RAY 2p1l H Reference
       Region 2p1l H 107-128 order
       Region 2p1l H 129-135 disorder
 Evidence NMR 2pon A Reference
       Region 2pon A 106-128 order
       Region 2pon A 128-128 high_rmsd
Seq 141-171 Homo trimer :
 Evidence X-RAY 5efm A Reference
       Region 5efm A 141-156 disorder
       Region 5efm A 157-171 order
Seq 175-265 Homo dimer :
 Evidence X-RAY 5hhe D Reference
       Region 5hhe D 175-265 order
 Evidence X-RAY 5hhe A Reference
       Region 5hhe A 175-265 order
Seq 241-450 Monomer :
 Evidence X-RAY 4ddp A Reference
       Region 4ddp A 241-247 disorder
       Region 4ddp A 248-264 order
       Region 4ddp A 265-268 disorder
       Region 4ddp A 269-386 order
       Region 4ddp A 387-387 disorder
       Region 4ddp A 388-447 order
       Region 4ddp A 448-450 disorder
SeqProS verified 106-129 Hetero dimer : P89884
       Region 4mi8 C 108-127 order
       Region 4mi8 D 107-127 order
       Region 3dvu C 106-129 order
       Region 3dvu D 105-128 order
       Region 105-140 disorder
SeqProS verified 106-129 Hetero dimer : Q07817
       Region 2pon A 106-128 order
       Region 2p1l B 107-128 order
       Region 2p1l D 107-128 order
       Region 2p1l F 107-128 order
       Region 2p1l H 107-128 order
       Region 105-140 disorder
Seqphosphorylation
    30-30 Phosphoserine
    90-90 Phosphoserine; by AMPK
    93-93 Phosphoserine; by AMPK
    96-96 Phosphoserine; by AMPK
    119-119 Phosphothreonine; by DAPK1
Seqacetylation
    1-1 N-acetylmethionine
 
Prediction
DICHOT
Disorder 1-105,167-194,448-450
Known Domain 106-128,195-447
Cryptic Domain 129-166
SCOPe RPS-Blast
     1w1wA 151-305 1e-06 c.37.1.12 ABC transporter involved in vitamin B...
Pfam RPS-Blast
     PF15285 105-129 2e-06 Beclin-1 BH3 domain, Bcl-2-...
     PF17675 135-261 7e-24 Apg6 coiled-coil region
     PF04111 264-443 1e-53 Apg6 BARA domain
Pfam Hmmer
    PF15285 105-129 1.4e-20 Beclin-1 BH3 domain, Bcl-2...
    PF17675 135-261 1.7e-34 Apg6 coiled-coil region
    PF04111 264-445 4.1e-80 Apg6 BARA domain