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IID00754
 UniprotO43172
ProteinU4/U6 small nuclear ribonucleoprotein Prp4
GenePRPF4
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
522
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 107-137 Hetero dimer : IID00757Complex
 Evidence X-RAY 1mzw B Reference
       Region 1mzw B 107-137 order
Seqacetylation
    27-27 N6-acetyllysine
 
Prediction
NeProc
Disorder 1-20,27-81,143-163
Order 21-26,82-142,164-522
ProS 27-46,60-81,143-147
AlphaFold
Disorder 1-39,41-41,43-59,61-61,63-79,143-143,155-169,286-286
Order 40-40,42-42,60-60,62-62,80-142,144-154,170-285,287-522
Pfam Hmmer
PF00400 221-259 0.00073
PF00400 263-309 6.5e-07
PF00400 313-351 8.6e-07
PF00400 355-393 9.2e-05
PF00400 397-435 7.6e-12
PF00400 439-478 4.3e-08
PF00400 482-520 1.3e-10
SEG 146-161
Function
Function in SwissProt
Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).