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IID00755
 UniprotO43290
ProteinU4/U6.U5 tri-snRNP-associated protein 1
GeneSART1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
800
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 117-135 Hetero dimer : IID00735Complex
 Evidence X-RAY 4pyu C Reference
       Region 4pyu C 117-135 order
 Evidence X-RAY 4pyu D Reference
       Region 4pyu D 117-135 order
 Evidence X-RAY 4pyu H Reference
       Region 4pyu H 117-135 order
 Evidence X-RAY 4pyu L Reference
       Region 4pyu L 117-135 order
 Evidence X-RAY 4pyu P Reference
       Region 4pyu P 117-135 order
 Evidence X-RAY 4pyu T Reference
       Region 4pyu T 117-135 order
Seqphosphorylation
    321-321 Phosphoserine
    761-761 Phosphoserine
    695-695 Phosphothreonine
    621-621 Phosphoserine
    598-598 Phosphoserine
    596-596 Phosphoserine
    591-591 Phosphoserine
    521-521 Phosphoserine
    486-486 Phosphoserine
    474-474 Phosphoserine
    448-448 Phosphoserine
    430-430 Phosphothreonine
    392-392 Phosphothreonine
    348-348 Phosphoserine
    789-789 Phosphoserine
    189-189 Phosphothreonine
    764-764 Phosphothreonine
 
Prediction
NeProc
Disorder 1-199,228-717,728-800
Order 200-227,718-727
ProS 5-11,33-44,60-63,114-140,150-199,228-361,374-382,388-402,415-444,463-468,473-477,487-513,523-530,551-566,602-610,623-652,665-717,728-735,745-754,770-794
AlphaFold
Disorder 1-117,138-156,188-188,190-198,311-312,316-331,343-343,399-399,401-492,536-551,564-629,653-695,697-697,760-766,788-800
Order 118-137,157-187,189-189,199-310,313-315,332-342,344-398,400-400,493-535,552-563,630-652,696-696,698-759,767-787
Pfam Hmmer
PF08648 1-157 0.00099
SEG 13-26 ,31-77 ,104-119 ,160-180 ,281-296 ,400-419 ,436-453 ,476-485 ,490-519
Function
Function in SwissProt
Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA.