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IID00763
UniprotO75807
ProteinProtein phosphatase 1 regulatory subunit 15A
GenePPP1R15A
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
674
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 552-579
 Evidence NMR Reference
       Region 552-579 disorder
Seq 552-591 Hetero dimer : IID00311Complex
 Evidence X-RAY 4xpn D Reference
       Region 4xpn D 552-553 disorder
       Region 4xpn D 554-567 order
       Region 4xpn D 568-591 disorder
 Evidence X-RAY 4xpn B Reference
       Region 4xpn B 552-552 disorder
       Region 4xpn B 553-568 order
       Region 4xpn B 569-591 disorder
Seq 582-621 Hetero hexamer : IID50082Complex,P00639
 Evidence X-RAY 7nxv E Reference
       Region 7nxv E 582-582 disorder
       Region 7nxv E 583-621 order
 Evidence X-RAY 7nxv C Reference
       Region 7nxv C 582-619 order
       Region 7nxv C 620-621 disorder
SeqProS verified 555-568 Hetero dimer : IID00311Complex
       Region 4xpn B 553-568 order
       Region 4xpn D 554-567 order
       Region 552-579 disorder
Seqphosphorylation
    143-143 Phosphoserine
    512-512 Phosphotyrosine
    434-434 Phosphotyrosine
    391-391 Phosphotyrosine
    262-262 Phosphotyrosine
 
Prediction
NeProc
Disorder 1-9,47-549,622-674
Order 10-46,550-621
ProS 1-5,47-61,74-77,92-119,132-141,148-152,180-189,217-224,255-264,300-307,338-347,383-395,429-439,473-493,510-516,521-536,646-653,665-674
AlphaFold
Disorder 1-511,522-522,537-552,568-578,624-674
Order 512-521,523-536,553-567,579-623
SEG 52-64 ,159-174 ,189-202 ,265-298 ,348-379 ,394-413 ,415-427 ,438-458 ,489-503 ,518-550 ,609-626 ,630-666
Function
Function in SwissProt
(Microbial infection) Promotes enterovirus 71 replication by mediating the internal ribosome entry site (IRES) activity of viral 5'-UTR.