Search Keyword:


Search option:


IID00766
UniprotP04198
ProteinN-myc proto-oncogene protein
GeneMYCN
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
464
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 28-89 Hetero dimer : IID00752Complex
 Evidence X-RAY 5g1x B Reference
       Region 5g1x B 28-60 disorder
       Region 5g1x B 61-89 order
Seq 28-89 Hetero dimer : IID00752Complex
 Evidence X-RAY 7ztl B Reference
       Region 7ztl B 28-71 disorder
       Region 7ztl B 72-89 order
SeqProS predicted 61-89 This region is predicted to be disordered by AlphaFold (pLDDT <68.5) and NeProc. Hetero dimer : IID00752Complex
       Region 7ztl B 72-89 order
SeqProS predicted 61-89 This region is predicted to be disordered by AlphaFold (pLDDT <68.5) and NeProc. Hetero dimer : IID00752Complex
       Region 5g1x B 61-89 order
Seqphosphorylation
    261-261 Phosphoserine; by CK2
    263-263 Phosphoserine; by CK2
 
Prediction
NeProc
Disorder 1-20,40-381
Order 21-39,382-464
ProS 7-20,47-68,74-117,137-140,187-201,210-217,225-231,238-252,274-284,295-300,330-335,368-381
AlphaFold
Disorder 1-48,50-61,63-76,78-122,135-185,195-275,277-277,279-374
Order 49-49,62-62,77-77,123-134,186-194,276-276,278-278,375-464
Pfam Hmmer
PF01056 9-372 5e-211
PF00010 382-434 4.3e-19
SEG 98-105 ,149-185 ,202-241 ,254-283 ,371-385 ,433-457
Function
Function in SwissProt
Positively regulates the transcription of MYCNOS in neuroblastoma cells.
Biological Process
Diagram with PDB data
MYCN/AURKACrystal structure of Aurora-A kinase in complex with N-Myc