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IID00786
 UniprotP18858
ProteinDNA ligase 1
GeneLIG1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
919
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 118-130 Hetero tetramer : IID00327Complex
 Evidence X-RAY 5yy9 D Reference
       Region 5yy9 D 118-127 order
       Region 5yy9 D 128-130 disorder
 Evidence X-RAY 5yy9 C Reference
       Region 5yy9 C 118-129 order
       Region 5yy9 C 130-130 disorder
Seq 233-919 Monomer :
 Evidence X-RAY 1x9n A Reference
       Region 1x9n A 233-261 disorder
       Region 1x9n A 262-384 order
       Region 1x9n A 385-392 disorder
       Region 1x9n A 393-901 order
       Region 1x9n A 902-919 disorder
 Evidence X-RAY 6p09 A Reference
       Region 6p09 A 262-901 order
       Region 6p09 A 902-904 disorder
 Evidence X-RAY 6p0a A Reference
       Region 6p0a A 262-386 order
       Region 6p0a A 387-389 disorder
       Region 6p0a A 390-901 order
       Region 6p0a A 902-904 disorder
 Evidence X-RAY 6p0b A Reference
       Region 6p0b A 262-901 order
       Region 6p0b A 902-904 disorder
 Evidence X-RAY 6p0c A Reference
       Region 6p0c A 262-901 order
       Region 6p0c A 902-904 disorder
 Evidence X-RAY 6p0d A Reference
       Region 6p0d A 262-901 order
       Region 6p0d A 902-904 disorder
 Evidence X-RAY 6p0e A Reference
       Region 6p0e A 262-901 order
       Region 6p0e A 902-904 disorder
 Evidence X-RAY 6q1v A Reference
       Region 6q1v A 262-901 order
       Region 6q1v A 902-904 disorder
 Evidence X-RAY 7kr3 A Reference
       Region 7kr3 A 262-387 order
       Region 7kr3 A 388-395 disorder
       Region 7kr3 A 396-901 order
       Region 7kr3 A 902-904 disorder
 Evidence X-RAY 7kr4 A Reference
       Region 7kr4 A 262-389 order
       Region 7kr4 A 390-394 disorder
       Region 7kr4 A 395-901 order
       Region 7kr4 A 902-904 disorder
 Evidence X-RAY 7l34 A Reference
       Region 7l34 A 262-386 order
       Region 7l34 A 387-390 disorder
       Region 7l34 A 391-900 order
       Region 7l34 A 901-906 disorder
 Evidence X-RAY 7l35 A Reference
       Region 7l35 A 262-386 order
       Region 7l35 A 387-394 disorder
       Region 7l35 A 395-901 order
       Region 7l35 A 902-906 disorder
Seqphosphorylation
    913-913 Phosphoserine
    911-911 Phosphoserine
    801-801 Phosphoserine
    819-819 Phosphoserine
    798-798 Phosphothreonine
    233-233 Phosphothreonine
    229-229 Phosphoserine
    230-230 Phosphoserine
    201-201 Phosphoserine
    207-207 Phosphothreonine
    195-195 Phosphothreonine
    199-199 Phosphoserine
    76-76 Phosphoserine
    141-141 Phosphoserine
    66-66 Phosphoserine
    51-51 Phosphoserine
    47-47 Phosphoserine
    49-49 Phosphoserine
Seqacetylation
    226-226 N6-acetyllysine
 
Prediction
NeProc
Disorder 1-129,159-268,389-396,417-422,902-919
Order 130-158,269-388,397-416,423-485,491-901
ProS 1-11,42-45,263-268,417-422,902-908,916-919
AlphaFold
Disorder 1-261,906-919
Order 262-905
Pfam Hmmer
PF04675 287-465 1.7e-95
PF01068 542-746 2.2e-103
PF04679 771-836 1.7e-28
SEG 11-24 ,141-168 ,181-192 ,209-217 ,237-260 ,344-355 ,444-454
Function
Function in SwissProt
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.