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IID00815
 UniprotP61587
ProteinRho-related GTP-binding protein RhoE
GeneRND3
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
244
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-200 Hetero dimer : Q13464
 Evidence X-RAY 2v55 D Reference
       Region 2v55 D 1-18 disorder
       Region 2v55 D 19-200 order
 Evidence X-RAY 2v55 B Reference
       Region 2v55 B 1-19 disorder
       Region 2v55 B 20-200 order
Seq 19-200 Monomer :
 Evidence X-RAY 1m7b A Reference
       Region 1m7b A 19-21 disorder
       Region 1m7b A 22-200 order
Seq 231-244 Hetero dimer : IID00301Complex
 Evidence X-RAY 8b2k B Reference
       Region 8b2k B 231-236 disorder
       Region 8b2k B 237-243 order
       Region 8b2k B 244-244 disorder
 Evidence X-RAY 8bfc B Reference
       Region 8bfc B 231-236 disorder
       Region 8bfc B 237-242 order
       Region 8bfc B 243-244 disorder
 Evidence X-RAY 7obc B Reference
       Region 7obc B 231-234 disorder
       Region 7obc B 235-241 order
 Evidence X-RAY 7obd B Reference
       Region 7obd B 231-235 disorder
       Region 7obd B 236-241 order
Seq 232-241 Hetero dimer : IID00061Complex
 Evidence X-RAY 4bg6 Q Reference
       Region 4bg6 Q 232-234 disorder
       Region 4bg6 Q 235-241 order
 Evidence X-RAY 4bg6 R Reference
       Region 4bg6 R 232-234 disorder
       Region 4bg6 R 235-241 order
SeqProS predicted 235-243 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00301Complex
       Region 7obd B 236-241 order
       Region 8bfc B 237-242 order
       Region 7obc B 235-241 order
       Region 8b2k B 237-243 order
SeqProS predicted 235-243 This region is predicted to be disordered by NeProc and AlphaFold (pLDDT < 68.5). Hetero dimer : IID00061Complex
       Region 4bg6 Q 235-241 order
       Region 4bg6 R 235-241 order
 
Prediction
NeProc
Disorder 1-20,202-244
Order 21-201
ProS 211-218,234-244
AlphaFold
Disorder 1-20,200-244
Order 21-199
Pfam Hmmer
PF00071 25-199 7.4e-55
SEG 198-209
Function
Function in SwissProt
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.