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IID00834
 UniprotQ14677
ProteinClathrin interactor 1
GeneCLINT1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
625
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-166 Monomer :
 Evidence X-RAY 1xgw A Reference
       Region 1xgw A 1-16 disorder
       Region 1xgw A 17-152 order
       Region 1xgw A 153-165 disorder
 Evidence X-RAY 2qy7 A Reference
       Region 2qy7 A 20-155 order
       Region 2qy7 A 156-166 disorder
 Evidence X-RAY 2qy7 B Reference
       Region 2qy7 B 20-155 order
       Region 2qy7 B 156-166 disorder
 Evidence X-RAY 2qy7 C Reference
       Region 2qy7 C 20-155 order
       Region 2qy7 C 156-166 disorder
Seq 20-166 Hetero dimer : Q9UEU0
 Evidence X-RAY 2v8s E Reference
       Region 2v8s E 20-21 disorder
       Region 2v8s E 22-158 order
       Region 2v8s E 159-166 disorder
Seqdisorder 291-426
 Evidence CD Reference
       Region 291-426 disorder
Seqphosphorylation
    163-163 Phosphoserine
    166-166 Phosphoserine
    173-173 Phosphoserine
    205-205 Phosphoserine
    210-210 Phosphoserine
    227-227 Phosphoserine
    245-245 Phosphoserine
    299-299 Phosphoserine
    308-308 Phosphothreonine
    624-624 Phosphoserine
    312-312 Phosphoserine
 
Prediction
NeProc
Disorder 156-625
Order 1-155
ProS 156-201,208-234,285-295,324-329,343-349,369-375,474-488,612-625
AlphaFold
Disorder 1-2,17-18,159-189,191-201,220-625
Order 3-16,19-158,190-190,202-219
Pfam Hmmer
PF01417 21-145 1.1e-76
SEG 141-158 ,262-279 ,308-323 ,338-359 ,429-440 ,504-521 ,571-600
Function
Function in SwissProt
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.