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IID00840
 UniprotQ16531
ProteinDNA damage-binding protein 1
GeneDDB1
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1140
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-1140 Hetero tetramer : IID00514Complex,P11207
 Evidence X-RAY 2hye A Reference
       Region 2hye A 1-1140 order
Seq 1-1140 Hetero tetramer : Q66K64,Q9BW61
 Evidence X-RAY 6pai A Reference
       Region 6pai A 1-1 disorder
       Region 6pai A 2-367 order
       Region 6pai A 368-370 disorder
       Region 6pai A 371-439 order
       Region 6pai A 440-441 disorder
       Region 6pai A 442-480 order
       Region 6pai A 481-482 disorder
       Region 6pai A 483-547 order
       Region 6pai A 548-550 disorder
       Region 6pai A 551-743 order
       Region 6pai A 744-748 disorder
       Region 6pai A 749-771 order
       Region 6pai A 772-783 disorder
       Region 6pai A 784-1015 order
       Region 6pai A 1016-1021 disorder
       Region 6pai A 1022-1114 order
       Region 6pai A 1115-1121 disorder
       Region 6pai A 1122-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bua G Reference
       Region 8bua G 1-394 order
       Region 8bua G 395-395 disorder
       Region 8bua G 706-708 disorder
       Region 8bua G 709-1140 order
 Evidence X-RAY 8bua D Reference
       Region 8bua D 1-394 order
       Region 8bua D 395-395 disorder
       Region 8bua D 706-707 disorder
       Region 8bua D 708-1140 order
 Evidence X-RAY 8bua A Reference
       Region 8bua A 1-393 order
       Region 8bua A 394-395 disorder
       Region 8bua A 706-707 disorder
       Region 8bua A 708-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu3 G Reference
       Region 8bu3 G 1-394 order
       Region 8bu3 G 395-395 disorder
       Region 8bu3 G 706-708 disorder
       Region 8bu3 G 709-1140 order
 Evidence X-RAY 8bu3 D Reference
       Region 8bu3 D 1-394 order
       Region 8bu3 D 395-395 disorder
       Region 8bu3 D 706-707 disorder
       Region 8bu3 D 708-1140 order
 Evidence X-RAY 8bu3 A Reference
       Region 8bu3 A 1-393 order
       Region 8bu3 A 394-395 disorder
       Region 8bu3 A 706-707 disorder
       Region 8bu3 A 708-1140 order
Seq 1-1140 Hetero dimer : P11207
 Evidence X-RAY 2b5l A Reference
       Region 2b5l A 1-773 order
       Region 2b5l A 774-779 disorder
       Region 2b5l A 780-1018 order
       Region 2b5l A 1019-1020 disorder
       Region 2b5l A 1021-1140 order
 Evidence X-RAY 2b5l B Reference
       Region 2b5l B 1-773 order
       Region 2b5l B 774-779 disorder
       Region 2b5l B 780-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu9 G Reference
       Region 8bu9 G 1-394 order
       Region 8bu9 G 395-395 disorder
       Region 8bu9 G 709-1140 order
 Evidence X-RAY 8bu9 D Reference
       Region 8bu9 D 1-394 order
       Region 8bu9 D 395-395 disorder
       Region 8bu9 D 709-1140 order
 Evidence X-RAY 8bu9 A Reference
       Region 8bu9 A 1-393 order
       Region 8bu9 A 394-395 disorder
       Region 8bu9 A 709-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu5 G Reference
       Region 8bu5 G 1-394 order
       Region 8bu5 G 395-395 disorder
       Region 8bu5 G 706-708 disorder
       Region 8bu5 G 709-1140 order
 Evidence X-RAY 8bu5 D Reference
       Region 8bu5 D 1-394 order
       Region 8bu5 D 395-395 disorder
       Region 8bu5 D 706-707 disorder
       Region 8bu5 D 708-1140 order
 Evidence X-RAY 8bu5 A Reference
       Region 8bu5 A 1-393 order
       Region 8bu5 A 394-395 disorder
       Region 8bu5 A 706-707 disorder
       Region 8bu5 A 708-1140 order
Seq 1-1140 Hetero tetramer : A4UDG5,IID00743Complex,P00720
 Evidence X-RAY 6zx9 A Reference
       Region 6zx9 A 1-288 order
       Region 6zx9 A 289-294 disorder
       Region 6zx9 A 295-1017 order
       Region 6zx9 A 1018-1022 disorder
       Region 6zx9 A 1023-1115 order
       Region 6zx9 A 1116-1122 disorder
       Region 6zx9 A 1123-1140 order
Seq 1-1140 Hetero tetramer : IID00743Complex
 Evidence X-RAY 5jk7 A Reference
       Region 5jk7 A 1-1017 order
       Region 5jk7 A 1018-1022 disorder
       Region 5jk7 A 1023-1116 order
       Region 5jk7 A 1117-1118 disorder
       Region 5jk7 A 1119-1140 order
 Evidence X-RAY 5jk7 B Reference
       Region 5jk7 B 1-1017 order
       Region 5jk7 B 1018-1022 disorder
       Region 5jk7 B 1023-1116 order
       Region 5jk7 B 1117-1118 disorder
       Region 5jk7 B 1119-1140 order
Seq 1-1140 Hetero trimer : Q96SW2
 Evidence X-RAY 6uml A Reference
       Region 6uml A 1-1 disorder
       Region 6uml A 2-46 order
       Region 6uml A 47-48 disorder
       Region 6uml A 49-93 order
       Region 6uml A 94-96 disorder
       Region 6uml A 97-369 order
       Region 6uml A 370-371 disorder
       Region 6uml A 372-546 order
       Region 6uml A 547-550 disorder
       Region 6uml A 551-576 order
       Region 6uml A 577-577 disorder
       Region 6uml A 578-625 order
       Region 6uml A 626-626 disorder
       Region 6uml A 627-745 order
       Region 6uml A 746-748 disorder
       Region 6uml A 749-771 order
       Region 6uml A 772-783 disorder
       Region 6uml A 784-980 order
       Region 6uml A 981-986 disorder
       Region 6uml A 987-1013 order
       Region 6uml A 1014-1023 disorder
       Region 6uml A 1024-1078 order
       Region 6uml A 1079-1080 disorder
       Region 6uml A 1081-1116 order
       Region 6uml A 1117-1120 disorder
       Region 6uml A 1121-1140 order
Seq 1-1140 Hetero dimer : IID00743Complex
 Evidence X-RAY 6zue A Reference
       Region 6zue A 1-288 order
       Region 6zue A 289-295 disorder
       Region 6zue A 296-548 order
       Region 6zue A 549-550 disorder
       Region 6zue A 551-744 order
       Region 6zue A 745-748 disorder
       Region 6zue A 749-772 order
       Region 6zue A 773-776 disorder
       Region 6zue A 777-1015 order
       Region 6zue A 1016-1024 disorder
       Region 6zue A 1025-1114 order
       Region 6zue A 1115-1122 disorder
       Region 6zue A 1123-1140 order
Seq 1-1140 Hetero dimer : Q5T6F0
 Evidence X-RAY 3i7p A Reference
       Region 3i7p A 1-773 order
       Region 3i7p A 774-782 disorder
       Region 3i7p A 783-1015 order
       Region 3i7p A 1016-1022 disorder
       Region 3i7p A 1023-1111 order
       Region 3i7p A 1112-1121 disorder
       Region 3i7p A 1122-1140 order
Seq 1-395,706-1140 Hetero hexadecamer : Q96SW2
 Evidence X-RAY 6h0f J Reference
       Region 6h0f J 1-395 order
       Region 6h0f J 706-1140 order
 Evidence X-RAY 6h0f G Reference
       Region 6h0f G 1-394 order
       Region 6h0f G 395-395 disorder
       Region 6h0f G 706-708 disorder
       Region 6h0f G 709-1140 order
 Evidence X-RAY 6h0f D Reference
       Region 6h0f D 1-394 order
       Region 6h0f D 395-395 disorder
       Region 6h0f D 706-707 disorder
       Region 6h0f D 708-1015 order
       Region 6h0f D 1016-1021 disorder
       Region 6h0f D 1022-1140 order
 Evidence X-RAY 6h0f A Reference
       Region 6h0f A 1-394 order
       Region 6h0f A 395-395 disorder
       Region 6h0f A 706-708 disorder
       Region 6h0f A 709-1140 order
Seq 1-395,706-1140 Hetero hexamer : Q66K64,Q9BW61
 Evidence X-RAY 6q0r A Reference
       Region 6q0r A 1-364 order
       Region 6q0r A 365-373 disorder
       Region 6q0r A 374-392 order
       Region 6q0r A 393-395 disorder
       Region 6q0r A 706-709 disorder
       Region 6q0r A 710-768 order
       Region 6q0r A 769-784 disorder
       Region 6q0r A 785-981 order
       Region 6q0r A 982-983 disorder
       Region 6q0r A 984-1009 order
       Region 6q0r A 1010-1022 disorder
       Region 6q0r A 1023-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bue G Reference
       Region 8bue G 1-394 order
       Region 8bue G 395-395 disorder
       Region 8bue G 709-1140 order
 Evidence X-RAY 8bue D Reference
       Region 8bue D 1-394 order
       Region 8bue D 395-395 disorder
       Region 8bue D 709-1140 order
 Evidence X-RAY 8bue A Reference
       Region 8bue A 1-393 order
       Region 8bue A 394-395 disorder
       Region 8bue A 709-1140 order
Seq 1-1140 Hetero dimer : Q96SW2
 Evidence X-RAY 4tz4 A Reference
       Region 4tz4 A 2-46 order
       Region 4tz4 A 47-48 disorder
       Region 4tz4 A 49-93 order
       Region 4tz4 A 94-96 disorder
       Region 4tz4 A 97-209 order
       Region 4tz4 A 210-210 disorder
       Region 4tz4 A 211-287 order
       Region 4tz4 A 288-295 disorder
       Region 4tz4 A 296-337 order
       Region 4tz4 A 338-341 disorder
       Region 4tz4 A 342-368 order
       Region 4tz4 A 369-371 disorder
       Region 4tz4 A 372-417 order
       Region 4tz4 A 418-419 disorder
       Region 4tz4 A 420-535 order
       Region 4tz4 A 536-537 disorder
       Region 4tz4 A 538-546 order
       Region 4tz4 A 547-550 disorder
       Region 4tz4 A 551-560 order
       Region 4tz4 A 561-561 disorder
       Region 4tz4 A 562-576 order
       Region 4tz4 A 577-577 disorder
       Region 4tz4 A 578-584 order
       Region 4tz4 A 585-585 disorder
       Region 4tz4 A 586-625 order
       Region 4tz4 A 626-626 disorder
       Region 4tz4 A 627-643 order
       Region 4tz4 A 644-644 disorder
       Region 4tz4 A 645-661 order
       Region 4tz4 A 662-662 disorder
       Region 4tz4 A 663-744 order
       Region 4tz4 A 745-748 disorder
       Region 4tz4 A 749-767 order
       Region 4tz4 A 768-783 disorder
       Region 4tz4 A 784-980 order
       Region 4tz4 A 981-986 disorder
       Region 4tz4 A 987-1013 order
       Region 4tz4 A 1014-1023 disorder
       Region 4tz4 A 1024-1078 order
       Region 4tz4 A 1079-1080 disorder
       Region 4tz4 A 1081-1117 order
       Region 4tz4 A 1118-1120 disorder
       Region 4tz4 A 1121-1140 order
 Evidence X-RAY 5v3o A Reference
       Region 5v3o A 1-1 disorder
       Region 5v3o A 2-209 order
       Region 5v3o A 210-210 disorder
       Region 5v3o A 211-287 order
       Region 5v3o A 288-295 disorder
       Region 5v3o A 296-546 order
       Region 5v3o A 547-550 disorder
       Region 5v3o A 551-744 order
       Region 5v3o A 745-748 disorder
       Region 5v3o A 749-769 order
       Region 5v3o A 770-783 disorder
       Region 5v3o A 784-980 order
       Region 5v3o A 981-986 disorder
       Region 5v3o A 987-1014 order
       Region 5v3o A 1015-1023 disorder
       Region 5v3o A 1024-1078 order
       Region 5v3o A 1079-1080 disorder
       Region 5v3o A 1081-1116 order
       Region 5v3o A 1117-1120 disorder
       Region 5v3o A 1121-1140 order
 Evidence X-RAY 8oiz A Reference
       Region 8oiz A 1-288 order
       Region 8oiz A 289-294 disorder
       Region 8oiz A 295-338 order
       Region 8oiz A 339-340 disorder
       Region 8oiz A 341-546 order
       Region 8oiz A 547-548 disorder
       Region 8oiz A 549-747 order
       Region 8oiz A 748-748 disorder
       Region 8oiz A 749-768 order
       Region 8oiz A 769-782 disorder
       Region 8oiz A 783-1014 order
       Region 8oiz A 1015-1022 disorder
       Region 8oiz A 1023-1140 order
 Evidence X-RAY 8ojh A Reference
       Region 8ojh A 1-288 order
       Region 8ojh A 289-295 disorder
       Region 8ojh A 296-338 order
       Region 8ojh A 339-340 disorder
       Region 8ojh A 341-367 order
       Region 8ojh A 368-369 disorder
       Region 8ojh A 370-546 order
       Region 8ojh A 547-550 disorder
       Region 8ojh A 551-747 order
       Region 8ojh A 748-748 disorder
       Region 8ojh A 749-768 order
       Region 8ojh A 769-781 disorder
       Region 8ojh A 782-981 order
       Region 8ojh A 982-982 disorder
       Region 8ojh A 983-1014 order
       Region 8ojh A 1015-1022 disorder
       Region 8ojh A 1023-1140 order
Seq 1-395,706-1140 Hetero hexamer : Q66K64,Q9BW61
 Evidence X-RAY 6q0v A Reference
       Region 6q0v A 1-364 order
       Region 6q0v A 365-373 disorder
       Region 6q0v A 374-392 order
       Region 6q0v A 393-395 disorder
       Region 6q0v A 706-709 disorder
       Region 6q0v A 710-767 order
       Region 6q0v A 768-784 disorder
       Region 6q0v A 785-981 order
       Region 6q0v A 982-983 disorder
       Region 6q0v A 984-1010 order
       Region 6q0v A 1011-1021 disorder
       Region 6q0v A 1022-1111 order
       Region 6q0v A 1112-1123 disorder
       Region 6q0v A 1124-1140 order
Seq 1-395,706-1140 Hetero octamer : Q96SW2
 Evidence X-RAY 8dey E Reference
       Region 8dey E 1-1 disorder
       Region 8dey E 2-144 order
       Region 8dey E 145-151 disorder
       Region 8dey E 152-287 order
       Region 8dey E 288-295 disorder
       Region 8dey E 296-393 order
       Region 8dey E 394-395 disorder
       Region 8dey E 706-708 disorder
       Region 8dey E 709-1014 order
       Region 8dey E 1015-1022 disorder
       Region 8dey E 1023-1140 order
 Evidence X-RAY 8dey B Reference
       Region 8dey B 1-1 disorder
       Region 8dey B 2-144 order
       Region 8dey B 145-151 disorder
       Region 8dey B 152-287 order
       Region 8dey B 288-295 disorder
       Region 8dey B 296-393 order
       Region 8dey B 394-395 disorder
       Region 8dey B 706-708 disorder
       Region 8dey B 709-1014 order
       Region 8dey B 1015-1022 disorder
       Region 8dey B 1023-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buj G Reference
       Region 8buj G 1-394 order
       Region 8buj G 395-395 disorder
       Region 8buj G 706-708 disorder
       Region 8buj G 709-1140 order
 Evidence X-RAY 8buj D Reference
       Region 8buj D 1-394 order
       Region 8buj D 395-395 disorder
       Region 8buj D 706-707 disorder
       Region 8buj D 708-1140 order
 Evidence X-RAY 8buj A Reference
       Region 8buj A 1-393 order
       Region 8buj A 394-395 disorder
       Region 8buj A 706-707 disorder
       Region 8buj A 708-1140 order
Seq 1-1140 Hetero trimer : Q96SW2
 Evidence X-RAY 5hxb Y Reference
       Region 5hxb Y 1-1 disorder
       Region 5hxb Y 2-46 order
       Region 5hxb Y 47-48 disorder
       Region 5hxb Y 49-93 order
       Region 5hxb Y 94-96 disorder
       Region 5hxb Y 97-209 order
       Region 5hxb Y 210-210 disorder
       Region 5hxb Y 211-287 order
       Region 5hxb Y 288-295 disorder
       Region 5hxb Y 296-366 order
       Region 5hxb Y 367-369 disorder
       Region 5hxb Y 370-417 order
       Region 5hxb Y 418-419 disorder
       Region 5hxb Y 420-546 order
       Region 5hxb Y 547-549 disorder
       Region 5hxb Y 550-584 order
       Region 5hxb Y 585-585 disorder
       Region 5hxb Y 586-643 order
       Region 5hxb Y 644-644 disorder
       Region 5hxb Y 645-661 order
       Region 5hxb Y 662-662 disorder
       Region 5hxb Y 663-744 order
       Region 5hxb Y 745-748 disorder
       Region 5hxb Y 749-770 order
       Region 5hxb Y 771-783 disorder
       Region 5hxb Y 784-980 order
       Region 5hxb Y 981-986 disorder
       Region 5hxb Y 987-1016 order
       Region 5hxb Y 1017-1022 disorder
       Region 5hxb Y 1023-1078 order
       Region 5hxb Y 1079-1080 disorder
       Region 5hxb Y 1081-1117 order
       Region 5hxb Y 1118-1120 disorder
       Region 5hxb Y 1121-1140 order
 Evidence X-RAY 5hxb B Reference
       Region 5hxb B 1-1 disorder
       Region 5hxb B 2-46 order
       Region 5hxb B 47-48 disorder
       Region 5hxb B 49-93 order
       Region 5hxb B 94-96 disorder
       Region 5hxb B 97-287 order
       Region 5hxb B 288-295 disorder
       Region 5hxb B 296-337 order
       Region 5hxb B 338-342 disorder
       Region 5hxb B 343-366 order
       Region 5hxb B 367-369 disorder
       Region 5hxb B 370-417 order
       Region 5hxb B 418-419 disorder
       Region 5hxb B 420-546 order
       Region 5hxb B 547-548 disorder
       Region 5hxb B 549-576 order
       Region 5hxb B 577-577 disorder
       Region 5hxb B 578-584 order
       Region 5hxb B 585-585 disorder
       Region 5hxb B 586-643 order
       Region 5hxb B 644-644 disorder
       Region 5hxb B 645-661 order
       Region 5hxb B 662-662 disorder
       Region 5hxb B 663-744 order
       Region 5hxb B 745-748 disorder
       Region 5hxb B 749-770 order
       Region 5hxb B 771-783 disorder
       Region 5hxb B 784-980 order
       Region 5hxb B 981-986 disorder
       Region 5hxb B 987-1016 order
       Region 5hxb B 1017-1023 disorder
       Region 5hxb B 1024-1078 order
       Region 5hxb B 1079-1080 disorder
       Region 5hxb B 1081-1117 order
       Region 5hxb B 1118-1120 disorder
       Region 5hxb B 1121-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buc G Reference
       Region 8buc G 1-394 order
       Region 8buc G 395-395 disorder
       Region 8buc G 709-1140 order
 Evidence X-RAY 8buc D Reference
       Region 8buc D 1-394 order
       Region 8buc D 395-395 disorder
       Region 8buc D 709-1140 order
 Evidence X-RAY 8buc A Reference
       Region 8buc A 1-393 order
       Region 8buc A 394-395 disorder
       Region 8buc A 709-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buq G Reference
       Region 8buq G 1-394 order
       Region 8buq G 395-395 disorder
       Region 8buq G 709-1140 order
 Evidence X-RAY 8buq D Reference
       Region 8buq D 1-394 order
       Region 8buq D 395-395 disorder
       Region 8buq D 709-1140 order
 Evidence X-RAY 8buq A Reference
       Region 8buq A 1-393 order
       Region 8buq A 394-395 disorder
       Region 8buq A 709-1015 order
       Region 8buq A 1016-1019 disorder
       Region 8buq A 1020-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buf G Reference
       Region 8buf G 1-394 order
       Region 8buf G 395-395 disorder
       Region 8buf G 709-1140 order
 Evidence X-RAY 8buf D Reference
       Region 8buf D 1-394 order
       Region 8buf D 395-395 disorder
       Region 8buf D 709-1140 order
 Evidence X-RAY 8buf A Reference
       Region 8buf A 1-393 order
       Region 8buf A 394-395 disorder
       Region 8buf A 709-1140 order
Seq 1-395,706-1140 Hetero octamer : Q96SW2
 Evidence X-RAY 7u8f E Reference
       Region 7u8f E 1-394 order
       Region 7u8f E 395-395 disorder
       Region 7u8f E 706-708 disorder
       Region 7u8f E 709-1140 order
 Evidence X-RAY 7u8f B Reference
       Region 7u8f B 1-394 order
       Region 7u8f B 395-395 disorder
       Region 7u8f B 706-708 disorder
       Region 7u8f B 709-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8but G Reference
       Region 8but G 1-394 order
       Region 8but G 395-395 disorder
       Region 8but G 709-1140 order
 Evidence X-RAY 8but D Reference
       Region 8but D 1-394 order
       Region 8but D 395-395 disorder
       Region 8but D 709-1140 order
 Evidence X-RAY 8but A Reference
       Region 8but A 1-393 order
       Region 8but A 394-395 disorder
       Region 8but A 709-1140 order
Seq 1-1140 Monomer :
 Evidence X-RAY 2b5m A Reference
       Region 2b5m A 1-773 order
       Region 2b5m A 774-778 disorder
       Region 2b5m A 779-1015 order
       Region 2b5m A 1016-1022 disorder
       Region 2b5m A 1023-1112 order
       Region 2b5m A 1113-1121 disorder
       Region 2b5m A 1122-1140 order
 Evidence X-RAY 3e0c A Reference
       Region 3e0c A 1-1 disorder
       Region 3e0c A 2-24 order
       Region 3e0c A 25-26 disorder
       Region 3e0c A 27-45 order
       Region 3e0c A 46-48 disorder
       Region 3e0c A 49-71 order
       Region 3e0c A 72-73 disorder
       Region 3e0c A 74-92 order
       Region 3e0c A 93-96 disorder
       Region 3e0c A 97-111 order
       Region 3e0c A 112-118 disorder
       Region 3e0c A 119-145 order
       Region 3e0c A 146-147 disorder
       Region 3e0c A 148-185 order
       Region 3e0c A 186-187 disorder
       Region 3e0c A 188-205 order
       Region 3e0c A 206-206 disorder
       Region 3e0c A 207-209 order
       Region 3e0c A 210-210 disorder
       Region 3e0c A 211-242 order
       Region 3e0c A 243-244 disorder
       Region 3e0c A 245-287 order
       Region 3e0c A 288-291 disorder
       Region 3e0c A 292-318 order
       Region 3e0c A 319-319 disorder
       Region 3e0c A 320-338 order
       Region 3e0c A 339-345 disorder
       Region 3e0c A 346-366 order
       Region 3e0c A 367-371 disorder
       Region 3e0c A 372-417 order
       Region 3e0c A 418-419 disorder
       Region 3e0c A 420-438 order
       Region 3e0c A 439-444 disorder
       Region 3e0c A 445-546 order
       Region 3e0c A 547-550 disorder
       Region 3e0c A 551-625 order
       Region 3e0c A 626-626 disorder
       Region 3e0c A 627-643 order
       Region 3e0c A 644-644 disorder
       Region 3e0c A 645-661 order
       Region 3e0c A 662-662 disorder
       Region 3e0c A 663-688 order
       Region 3e0c A 689-689 disorder
       Region 3e0c A 690-742 order
       Region 3e0c A 743-750 disorder
       Region 3e0c A 751-766 order
       Region 3e0c A 767-785 disorder
       Region 3e0c A 786-838 order
       Region 3e0c A 839-841 disorder
       Region 3e0c A 842-853 order
       Region 3e0c A 854-855 disorder
       Region 3e0c A 856-978 order
       Region 3e0c A 979-989 disorder
       Region 3e0c A 990-1013 order
       Region 3e0c A 1014-1023 disorder
       Region 3e0c A 1024-1079 order
       Region 3e0c A 1080-1081 disorder
       Region 3e0c A 1082-1110 order
       Region 3e0c A 1111-1124 disorder
       Region 3e0c A 1125-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buk G Reference
       Region 8buk G 1-394 order
       Region 8buk G 395-395 disorder
       Region 8buk G 709-1140 order
 Evidence X-RAY 8buk D Reference
       Region 8buk D 1-394 order
       Region 8buk D 395-395 disorder
       Region 8buk D 709-1140 order
 Evidence X-RAY 8buk A Reference
       Region 8buk A 1-393 order
       Region 8buk A 394-395 disorder
       Region 8buk A 709-1140 order
Seq 1-395,708-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 6td3 G Reference
       Region 6td3 G 1-394 order
       Region 6td3 G 395-395 disorder
       Region 6td3 G 708-708 disorder
       Region 6td3 G 709-1140 order
 Evidence X-RAY 6td3 D Reference
       Region 6td3 D 1-394 order
       Region 6td3 D 395-395 disorder
       Region 6td3 D 708-1140 order
 Evidence X-RAY 6td3 A Reference
       Region 6td3 A 1-393 order
       Region 6td3 A 394-395 disorder
       Region 6td3 A 708-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu2 G Reference
       Region 8bu2 G 1-394 order
       Region 8bu2 G 395-395 disorder
       Region 8bu2 G 709-1140 order
 Evidence X-RAY 8bu2 D Reference
       Region 8bu2 D 1-394 order
       Region 8bu2 D 395-395 disorder
       Region 8bu2 D 709-1140 order
 Evidence X-RAY 8bu2 A Reference
       Region 8bu2 A 1-393 order
       Region 8bu2 A 394-395 disorder
       Region 8bu2 A 709-1140 order
Seq 1-1140 Hetero dodecamer : Q96SW2
 Evidence X-RAY 7lps J Reference
       Region 7lps J 1-287 order
       Region 7lps J 288-294 disorder
       Region 7lps J 295-336 order
       Region 7lps J 337-346 disorder
       Region 7lps J 347-393 order
       Region 7lps J 394-708 disorder
       Region 7lps J 709-770 order
       Region 7lps J 771-781 disorder
       Region 7lps J 782-1015 order
       Region 7lps J 1016-1020 disorder
       Region 7lps J 1021-1111 order
       Region 7lps J 1112-1124 disorder
       Region 7lps J 1125-1140 order
 Evidence X-RAY 7lps G Reference
       Region 7lps G 1-287 order
       Region 7lps G 288-294 disorder
       Region 7lps G 295-336 order
       Region 7lps G 337-346 disorder
       Region 7lps G 347-393 order
       Region 7lps G 394-708 disorder
       Region 7lps G 709-770 order
       Region 7lps G 771-781 disorder
       Region 7lps G 782-1015 order
       Region 7lps G 1016-1020 disorder
       Region 7lps G 1021-1111 order
       Region 7lps G 1112-1124 disorder
       Region 7lps G 1125-1140 order
 Evidence X-RAY 7lps D Reference
       Region 7lps D 1-287 order
       Region 7lps D 288-294 disorder
       Region 7lps D 295-338 order
       Region 7lps D 339-346 disorder
       Region 7lps D 347-393 order
       Region 7lps D 394-708 disorder
       Region 7lps D 709-770 order
       Region 7lps D 771-781 disorder
       Region 7lps D 782-1015 order
       Region 7lps D 1016-1020 disorder
       Region 7lps D 1021-1111 order
       Region 7lps D 1112-1124 disorder
       Region 7lps D 1125-1140 order
 Evidence X-RAY 7lps A Reference
       Region 7lps A 1-287 order
       Region 7lps A 288-294 disorder
       Region 7lps A 295-338 order
       Region 7lps A 339-346 disorder
       Region 7lps A 347-393 order
       Region 7lps A 394-708 disorder
       Region 7lps A 709-770 order
       Region 7lps A 771-781 disorder
       Region 7lps A 782-1015 order
       Region 7lps A 1016-1020 disorder
       Region 7lps A 1021-1111 order
       Region 7lps A 1112-1124 disorder
       Region 7lps A 1125-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu1 G Reference
       Region 8bu1 G 1-394 order
       Region 8bu1 G 395-395 disorder
       Region 8bu1 G 709-1140 order
 Evidence X-RAY 8bu1 D Reference
       Region 8bu1 D 1-394 order
       Region 8bu1 D 395-395 disorder
       Region 8bu1 D 709-1140 order
 Evidence X-RAY 8bu1 A Reference
       Region 8bu1 A 1-393 order
       Region 8bu1 A 394-395 disorder
       Region 8bu1 A 709-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buh G Reference
       Region 8buh G 1-394 order
       Region 8buh G 395-395 disorder
       Region 8buh G 709-1140 order
 Evidence X-RAY 8buh D Reference
       Region 8buh D 1-394 order
       Region 8buh D 395-395 disorder
       Region 8buh D 709-1140 order
 Evidence X-RAY 8buh A Reference
       Region 8buh A 1-393 order
       Region 8buh A 394-395 disorder
       Region 8buh A 709-1140 order
Seq 1-1140 Hetero tetramer : Q9BW61
 Evidence X-RAY 6dsz B Reference
       Region 6dsz B 1-93 order
       Region 6dsz B 94-97 disorder
       Region 6dsz B 98-367 order
       Region 6dsz B 368-368 disorder
       Region 6dsz B 369-402 order
       Region 6dsz B 403-406 disorder
       Region 6dsz B 407-415 order
       Region 6dsz B 416-418 disorder
       Region 6dsz B 419-442 order
       Region 6dsz B 443-447 disorder
       Region 6dsz B 448-454 order
       Region 6dsz B 455-455 disorder
       Region 6dsz B 456-545 order
       Region 6dsz B 546-550 disorder
       Region 6dsz B 551-597 order
       Region 6dsz B 598-599 disorder
       Region 6dsz B 600-623 order
       Region 6dsz B 624-624 disorder
       Region 6dsz B 625-659 order
       Region 6dsz B 660-665 disorder
       Region 6dsz B 666-744 order
       Region 6dsz B 745-747 disorder
       Region 6dsz B 748-773 order
       Region 6dsz B 774-780 disorder
       Region 6dsz B 781-901 order
       Region 6dsz B 902-904 disorder
       Region 6dsz B 905-1015 order
       Region 6dsz B 1016-1022 disorder
       Region 6dsz B 1023-1109 order
       Region 6dsz B 1110-1125 disorder
       Region 6dsz B 1126-1140 order
 Evidence X-RAY 6dsz A Reference
       Region 6dsz A 1-545 order
       Region 6dsz A 546-550 disorder
       Region 6dsz A 551-623 order
       Region 6dsz A 624-624 disorder
       Region 6dsz A 625-773 order
       Region 6dsz A 774-779 disorder
       Region 6dsz A 780-901 order
       Region 6dsz A 902-904 disorder
       Region 6dsz A 905-1015 order
       Region 6dsz A 1016-1022 disorder
       Region 6dsz A 1023-1112 order
       Region 6dsz A 1113-1123 disorder
       Region 6dsz A 1124-1140 order
Seq 1-1140 Hetero dimer : Q5TAQ9
 Evidence X-RAY 3i8e A Reference
       Region 3i8e A 1-773 order
       Region 3i8e A 774-782 disorder
       Region 3i8e A 783-1015 order
       Region 3i8e A 1016-1022 disorder
       Region 3i8e A 1023-1111 order
       Region 3i8e A 1112-1121 disorder
       Region 3i8e A 1122-1140 order
 Evidence X-RAY 3i8e B Reference
       Region 3i8e B 1-773 order
       Region 3i8e B 774-782 disorder
       Region 3i8e B 783-1015 order
       Region 3i8e B 1016-1022 disorder
       Region 3i8e B 1023-1111 order
       Region 3i8e B 1112-1121 disorder
       Region 3i8e B 1122-1140 order
Seq 1-395,706-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 6bn7 A Reference
       Region 6bn7 A 1-287 order
       Region 6bn7 A 288-294 disorder
       Region 6bn7 A 295-393 order
       Region 6bn7 A 394-395 disorder
       Region 6bn7 A 706-708 disorder
       Region 6bn7 A 709-769 order
       Region 6bn7 A 770-775 disorder
       Region 6bn7 A 776-1015 order
       Region 6bn7 A 1016-1021 disorder
       Region 6bn7 A 1022-1112 order
       Region 6bn7 A 1113-1115 disorder
       Region 6bn7 A 1116-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bun G Reference
       Region 8bun G 1-394 order
       Region 8bun G 395-395 disorder
       Region 8bun G 709-1140 order
 Evidence X-RAY 8bun D Reference
       Region 8bun D 1-394 order
       Region 8bun D 395-395 disorder
       Region 8bun D 709-1140 order
 Evidence X-RAY 8bun A Reference
       Region 8bun A 1-393 order
       Region 8bun A 394-395 disorder
       Region 8bun A 709-1140 order
Seq 1-1140 Hetero dimer : IID00854Complex
 Evidence X-RAY 3ei4 A Reference
       Region 3ei4 A 1-1140 order
 Evidence X-RAY 3ei4 C Reference
       Region 3ei4 C 1-1140 order
 Evidence X-RAY 3ei4 E Reference
       Region 3ei4 E 1-1140 order
 Evidence X-RAY 4e54 A Reference
       Region 4e54 A 2-1140 order
 Evidence X-RAY 4e5z A Reference
       Region 4e5z A 2-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bul G Reference
       Region 8bul G 1-394 order
       Region 8bul G 395-395 disorder
       Region 8bul G 706-708 disorder
       Region 8bul G 709-1140 order
 Evidence X-RAY 8bul D Reference
       Region 8bul D 1-394 order
       Region 8bul D 395-395 disorder
       Region 8bul D 706-707 disorder
       Region 8bul D 708-1140 order
 Evidence X-RAY 8bul A Reference
       Region 8bul A 1-393 order
       Region 8bul A 394-395 disorder
       Region 8bul A 706-707 disorder
       Region 8bul A 708-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bup G Reference
       Region 8bup G 1-394 order
       Region 8bup G 395-395 disorder
       Region 8bup G 709-1140 order
 Evidence X-RAY 8bup D Reference
       Region 8bup D 1-394 order
       Region 8bup D 395-395 disorder
       Region 8bup D 709-1140 order
 Evidence X-RAY 8bup A Reference
       Region 8bup A 1-393 order
       Region 8bup A 394-395 disorder
       Region 8bup A 709-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bum G Reference
       Region 8bum G 1-394 order
       Region 8bum G 395-395 disorder
       Region 8bum G 706-708 disorder
       Region 8bum G 709-1140 order
 Evidence X-RAY 8bum D Reference
       Region 8bum D 1-394 order
       Region 8bum D 395-395 disorder
       Region 8bum D 706-707 disorder
       Region 8bum D 708-1140 order
 Evidence X-RAY 8bum A Reference
       Region 8bum A 1-393 order
       Region 8bum A 394-395 disorder
       Region 8bum A 706-707 disorder
       Region 8bum A 708-1140 order
Seq 1-1140 Hetero dimer : IID00826Complex
 Evidence X-RAY 4a11 A Reference
       Region 4a11 A 1-287 order
       Region 4a11 A 288-293 disorder
       Region 4a11 A 294-337 order
       Region 4a11 A 338-344 disorder
       Region 4a11 A 345-743 order
       Region 4a11 A 744-747 disorder
       Region 4a11 A 748-772 order
       Region 4a11 A 773-783 disorder
       Region 4a11 A 784-981 order
       Region 4a11 A 982-984 disorder
       Region 4a11 A 985-1014 order
       Region 4a11 A 1015-1022 disorder
       Region 4a11 A 1023-1113 order
       Region 4a11 A 1114-1123 disorder
       Region 4a11 A 1124-1140 order
 Evidence X-RAY 6fcv A Reference
       Region 6fcv A 1-287 order
       Region 6fcv A 288-293 disorder
       Region 6fcv A 294-337 order
       Region 6fcv A 338-344 disorder
       Region 6fcv A 345-743 order
       Region 6fcv A 744-747 disorder
       Region 6fcv A 748-772 order
       Region 6fcv A 773-783 disorder
       Region 6fcv A 784-981 order
       Region 6fcv A 982-984 disorder
       Region 6fcv A 985-1014 order
       Region 6fcv A 1015-1022 disorder
       Region 6fcv A 1023-1113 order
       Region 6fcv A 1114-1123 disorder
       Region 6fcv A 1124-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8buo G Reference
       Region 8buo G 1-394 order
       Region 8buo G 395-395 disorder
       Region 8buo G 706-708 disorder
       Region 8buo G 709-1140 order
 Evidence X-RAY 8buo D Reference
       Region 8buo D 1-394 order
       Region 8buo D 395-395 disorder
       Region 8buo D 706-707 disorder
       Region 8buo D 708-1140 order
 Evidence X-RAY 8buo A Reference
       Region 8buo A 1-393 order
       Region 8buo A 394-395 disorder
       Region 8buo A 706-707 disorder
       Region 8buo A 708-1140 order
Seq 1-1140 Hetero hexamer : Q96SW2
 Evidence X-RAY 6xk9 Y Reference
       Region 6xk9 Y 1-1 disorder
       Region 6xk9 Y 2-46 order
       Region 6xk9 Y 47-48 disorder
       Region 6xk9 Y 49-417 order
       Region 6xk9 Y 418-419 disorder
       Region 6xk9 Y 420-661 order
       Region 6xk9 Y 662-662 disorder
       Region 6xk9 Y 663-770 order
       Region 6xk9 Y 771-783 disorder
       Region 6xk9 Y 784-980 order
       Region 6xk9 Y 981-986 disorder
       Region 6xk9 Y 987-1015 order
       Region 6xk9 Y 1016-1021 disorder
       Region 6xk9 Y 1022-1117 order
       Region 6xk9 Y 1118-1120 disorder
       Region 6xk9 Y 1121-1140 order
 Evidence X-RAY 6xk9 B Reference
       Region 6xk9 B 1-1 disorder
       Region 6xk9 B 2-46 order
       Region 6xk9 B 47-48 disorder
       Region 6xk9 B 49-93 order
       Region 6xk9 B 94-96 disorder
       Region 6xk9 B 97-287 order
       Region 6xk9 B 288-295 disorder
       Region 6xk9 B 296-366 order
       Region 6xk9 B 367-369 disorder
       Region 6xk9 B 370-417 order
       Region 6xk9 B 418-419 disorder
       Region 6xk9 B 420-546 order
       Region 6xk9 B 547-549 disorder
       Region 6xk9 B 550-744 order
       Region 6xk9 B 745-748 disorder
       Region 6xk9 B 749-770 order
       Region 6xk9 B 771-783 disorder
       Region 6xk9 B 784-980 order
       Region 6xk9 B 981-986 disorder
       Region 6xk9 B 987-1015 order
       Region 6xk9 B 1016-1022 disorder
       Region 6xk9 B 1023-1117 order
       Region 6xk9 B 1118-1120 disorder
       Region 6xk9 B 1121-1140 order
Seq 1-1140 Hetero dimer : Q58WW2
 Evidence X-RAY 3i7o A Reference
       Region 3i7o A 1-773 order
       Region 3i7o A 774-782 disorder
       Region 3i7o A 783-1015 order
       Region 3i7o A 1016-1022 disorder
       Region 3i7o A 1023-1111 order
       Region 3i7o A 1112-1121 disorder
       Region 3i7o A 1122-1140 order
Seq 1-1140 Hetero dimer : Q8WV16
 Evidence X-RAY 3i8c A Reference
       Region 3i8c A 1-773 order
       Region 3i8c A 774-782 disorder
       Region 3i8c A 783-1015 order
       Region 3i8c A 1016-1022 disorder
       Region 3i8c A 1023-1111 order
       Region 3i8c A 1112-1121 disorder
       Region 3i8c A 1122-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bub G Reference
       Region 8bub G 1-394 order
       Region 8bub G 395-395 disorder
       Region 8bub G 709-1140 order
 Evidence X-RAY 8bub D Reference
       Region 8bub D 1-394 order
       Region 8bub D 395-395 disorder
       Region 8bub D 709-1140 order
 Evidence X-RAY 8bub A Reference
       Region 8bub A 1-393 order
       Region 8bub A 394-395 disorder
       Region 8bub A 709-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bui G Reference
       Region 8bui G 1-394 order
       Region 8bui G 395-395 disorder
       Region 8bui G 706-708 disorder
       Region 8bui G 709-1140 order
 Evidence X-RAY 8bui D Reference
       Region 8bui D 1-394 order
       Region 8bui D 395-395 disorder
       Region 8bui D 706-707 disorder
       Region 8bui D 708-1140 order
 Evidence X-RAY 8bui A Reference
       Region 8bui A 1-393 order
       Region 8bui A 394-395 disorder
       Region 8bui A 706-707 disorder
       Region 8bui A 708-1140 order
Seq 1-395,706-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 6bn9 A Reference
       Region 6bn9 A 1-287 order
       Region 6bn9 A 288-294 disorder
       Region 6bn9 A 295-393 order
       Region 6bn9 A 394-395 disorder
       Region 6bn9 A 706-708 disorder
       Region 6bn9 A 709-770 order
       Region 6bn9 A 771-775 disorder
       Region 6bn9 A 776-1015 order
       Region 6bn9 A 1016-1020 disorder
       Region 6bn9 A 1021-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu7 G Reference
       Region 8bu7 G 1-394 order
       Region 8bu7 G 395-395 disorder
       Region 8bu7 G 706-708 disorder
       Region 8bu7 G 709-1140 order
 Evidence X-RAY 8bu7 D Reference
       Region 8bu7 D 1-394 order
       Region 8bu7 D 395-395 disorder
       Region 8bu7 D 706-707 disorder
       Region 8bu7 D 708-1140 order
 Evidence X-RAY 8bu7 A Reference
       Region 8bu7 A 1-393 order
       Region 8bu7 A 394-395 disorder
       Region 8bu7 A 706-707 disorder
       Region 8bu7 A 708-1140 order
Seq 1-395,706-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bus G Reference
       Region 8bus G 1-394 order
       Region 8bus G 395-395 disorder
       Region 8bus G 706-708 disorder
       Region 8bus G 709-1140 order
 Evidence X-RAY 8bus D Reference
       Region 8bus D 1-393 order
       Region 8bus D 394-395 disorder
       Region 8bus D 706-707 disorder
       Region 8bus D 708-1140 order
 Evidence X-RAY 8bus A Reference
       Region 8bus A 1-394 order
       Region 8bus A 395-395 disorder
       Region 8bus A 706-707 disorder
       Region 8bus A 708-1140 order
Seq 1-1140 Hetero dimer : Q2YDS1
 Evidence X-RAY 3ei1 A Reference
       Region 3ei1 A 1-290 order
       Region 3ei1 A 291-294 disorder
       Region 3ei1 A 295-547 order
       Region 3ei1 A 548-550 disorder
       Region 3ei1 A 551-771 order
       Region 3ei1 A 772-782 disorder
       Region 3ei1 A 783-1015 order
       Region 3ei1 A 1016-1022 disorder
       Region 3ei1 A 1023-1113 order
       Region 3ei1 A 1114-1123 disorder
       Region 3ei1 A 1124-1140 order
 Evidence X-RAY 3ei2 A Reference
       Region 3ei2 A 1-290 order
       Region 3ei2 A 291-294 disorder
       Region 3ei2 A 295-548 order
       Region 3ei2 A 549-550 disorder
       Region 3ei2 A 551-771 order
       Region 3ei2 A 772-783 disorder
       Region 3ei2 A 784-1015 order
       Region 3ei2 A 1016-1022 disorder
       Region 3ei2 A 1023-1111 order
       Region 3ei2 A 1112-1123 disorder
       Region 3ei2 A 1124-1140 order
 Evidence X-RAY 3ei3 A Reference
       Region 3ei3 A 1-93 order
       Region 3ei3 A 94-94 disorder
       Region 3ei3 A 95-289 order
       Region 3ei3 A 290-294 disorder
       Region 3ei3 A 295-771 order
       Region 3ei3 A 772-781 disorder
       Region 3ei3 A 782-1015 order
       Region 3ei3 A 1016-1022 disorder
       Region 3ei3 A 1023-1112 order
       Region 3ei3 A 1113-1124 disorder
       Region 3ei3 A 1125-1140 order
 Evidence X-RAY 4a08 A Reference
       Region 4a08 A 1-1 disorder
       Region 4a08 A 2-93 order
       Region 4a08 A 94-97 disorder
       Region 4a08 A 98-287 order
       Region 4a08 A 288-294 disorder
       Region 4a08 A 295-370 order
       Region 4a08 A 371-372 disorder
       Region 4a08 A 373-438 order
       Region 4a08 A 439-442 disorder
       Region 4a08 A 443-743 order
       Region 4a08 A 744-746 disorder
       Region 4a08 A 747-771 order
       Region 4a08 A 772-783 disorder
       Region 4a08 A 784-980 order
       Region 4a08 A 981-989 disorder
       Region 4a08 A 990-1013 order
       Region 4a08 A 1014-1023 disorder
       Region 4a08 A 1024-1140 order
 Evidence X-RAY 4a09 A Reference
       Region 4a09 A 1-289 order
       Region 4a09 A 290-294 disorder
       Region 4a09 A 295-771 order
       Region 4a09 A 772-783 disorder
       Region 4a09 A 784-1015 order
       Region 4a09 A 1016-1022 disorder
       Region 4a09 A 1023-1111 order
       Region 4a09 A 1112-1122 disorder
       Region 4a09 A 1123-1140 order
 Evidence X-RAY 4a0a A Reference
       Region 4a0a A 1-290 order
       Region 4a0a A 291-294 disorder
       Region 4a0a A 295-392 order
       Region 4a0a A 393-708 disorder
       Region 4a0a A 709-741 order
       Region 4a0a A 742-748 disorder
       Region 4a0a A 749-771 order
       Region 4a0a A 772-784 disorder
       Region 4a0a A 785-981 order
       Region 4a0a A 982-984 disorder
       Region 4a0a A 985-1015 order
       Region 4a0a A 1016-1022 disorder
       Region 4a0a A 1023-1113 order
       Region 4a0a A 1114-1123 disorder
       Region 4a0a A 1124-1140 order
 Evidence X-RAY 4a0b A Reference
       Region 4a0b A 1-3 disorder
       Region 4a0b A 4-290 order
       Region 4a0b A 291-294 disorder
       Region 4a0b A 295-438 order
       Region 4a0b A 439-442 disorder
       Region 4a0b A 443-771 order
       Region 4a0b A 772-783 disorder
       Region 4a0b A 784-980 order
       Region 4a0b A 981-986 disorder
       Region 4a0b A 987-1015 order
       Region 4a0b A 1016-1021 disorder
       Region 4a0b A 1022-1111 order
       Region 4a0b A 1112-1126 disorder
       Region 4a0b A 1127-1140 order
 Evidence X-RAY 4a0b C Reference
       Region 4a0b C 1-288 order
       Region 4a0b C 289-294 disorder
       Region 4a0b C 295-439 order
       Region 4a0b C 440-444 disorder
       Region 4a0b C 445-582 order
       Region 4a0b C 583-585 disorder
       Region 4a0b C 586-771 order
       Region 4a0b C 772-783 disorder
       Region 4a0b C 784-1015 order
       Region 4a0b C 1016-1022 disorder
       Region 4a0b C 1023-1111 order
       Region 4a0b C 1112-1123 disorder
       Region 4a0b C 1124-1140 order
Seq 1-1140 Hetero dimer : Q80IU5
 Evidence X-RAY 3i7h A Reference
       Region 3i7h A 1-773 order
       Region 3i7h A 774-782 disorder
       Region 3i7h A 783-1015 order
       Region 3i7h A 1016-1022 disorder
       Region 3i7h A 1023-1111 order
       Region 3i7h A 1112-1121 disorder
       Region 3i7h A 1122-1140 order
Seq 1-1140 Hetero dimer : P0CF65
 Evidence X-RAY 4ci1 A Reference
       Region 4ci1 A 1-1 disorder
       Region 4ci1 A 2-145 order
       Region 4ci1 A 146-149 disorder
       Region 4ci1 A 150-285 order
       Region 4ci1 A 286-299 disorder
       Region 4ci1 A 300-771 order
       Region 4ci1 A 772-783 disorder
       Region 4ci1 A 784-979 order
       Region 4ci1 A 980-983 disorder
       Region 4ci1 A 984-1014 order
       Region 4ci1 A 1015-1021 disorder
       Region 4ci1 A 1022-1113 order
       Region 4ci1 A 1114-1120 disorder
       Region 4ci1 A 1121-1140 order
 Evidence X-RAY 4ci2 A Reference
       Region 4ci2 A 1-1 disorder
       Region 4ci2 A 2-145 order
       Region 4ci2 A 146-149 disorder
       Region 4ci2 A 150-285 order
       Region 4ci2 A 286-299 disorder
       Region 4ci2 A 300-771 order
       Region 4ci2 A 772-783 disorder
       Region 4ci2 A 784-979 order
       Region 4ci2 A 980-983 disorder
       Region 4ci2 A 984-1014 order
       Region 4ci2 A 1015-1021 disorder
       Region 4ci2 A 1022-1113 order
       Region 4ci2 A 1114-1120 disorder
       Region 4ci2 A 1121-1140 order
 Evidence X-RAY 4ci3 A Reference
       Region 4ci3 A 1-1 disorder
       Region 4ci3 A 2-145 order
       Region 4ci3 A 146-149 disorder
       Region 4ci3 A 150-285 order
       Region 4ci3 A 286-299 disorder
       Region 4ci3 A 300-771 order
       Region 4ci3 A 772-783 disorder
       Region 4ci3 A 784-979 order
       Region 4ci3 A 980-983 disorder
       Region 4ci3 A 984-1014 order
       Region 4ci3 A 1015-1021 disorder
       Region 4ci3 A 1022-1113 order
       Region 4ci3 A 1114-1120 disorder
       Region 4ci3 A 1121-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bud G Reference
       Region 8bud G 1-394 order
       Region 8bud G 395-395 disorder
       Region 8bud G 709-1140 order
 Evidence X-RAY 8bud D Reference
       Region 8bud D 1-394 order
       Region 8bud D 395-395 disorder
       Region 8bud D 709-1140 order
 Evidence X-RAY 8bud A Reference
       Region 8bud A 1-393 order
       Region 8bud A 394-395 disorder
       Region 8bud A 709-1140 order
Seq 1-1140 Hetero dimer : P03167
 Evidence X-RAY 3i7k A Reference
       Region 3i7k A 1-773 order
       Region 3i7k A 774-782 disorder
       Region 3i7k A 783-1015 order
       Region 3i7k A 1016-1022 disorder
       Region 3i7k A 1023-1111 order
       Region 3i7k A 1112-1121 disorder
       Region 3i7k A 1122-1140 order
Seq 1-395,461-462,702-1140 Hetero hexamer : Q96SW2
 Evidence X-RAY 6h0g D Reference
       Region 6h0g D 1-393 order
       Region 6h0g D 394-395 disorder
       Region 6h0g D 461-462 disorder
       Region 6h0g D 702-708 disorder
       Region 6h0g D 709-1140 order
 Evidence X-RAY 6h0g A Reference
       Region 6h0g A 1-393 order
       Region 6h0g A 394-395 disorder
       Region 6h0g A 461-462 disorder
       Region 6h0g A 702-708 disorder
       Region 6h0g A 709-1140 order
Seq 1-1140 Hetero dimer : Q96JK2
 Evidence X-RAY 3i89 A Reference
       Region 3i89 A 1-773 order
       Region 3i89 A 774-782 disorder
       Region 3i89 A 783-1015 order
       Region 3i89 A 1016-1022 disorder
       Region 3i89 A 1023-1111 order
       Region 3i89 A 1112-1121 disorder
       Region 3i89 A 1122-1140 order
Seq 1-395,706-1140 Hetero pentamer : Q66K64,Q9BW61
 Evidence X-RAY 6ud7 B Reference
       Region 6ud7 B 1-1 disorder
       Region 6ud7 B 2-395 order
       Region 6ud7 B 706-708 disorder
       Region 6ud7 B 709-773 order
       Region 6ud7 B 774-779 disorder
       Region 6ud7 B 780-1110 order
       Region 6ud7 B 1111-1124 disorder
       Region 6ud7 B 1125-1140 order
Seq 1-395,706-1140 Hetero hexamer : Q66K64,Q9BW61
 Evidence X-RAY 6q0w A Reference
       Region 6q0w A 1-392 order
       Region 6q0w A 393-395 disorder
       Region 6q0w A 706-709 disorder
       Region 6q0w A 710-767 order
       Region 6q0w A 768-784 disorder
       Region 6q0w A 785-981 order
       Region 6q0w A 982-983 disorder
       Region 6q0w A 984-1010 order
       Region 6q0w A 1011-1021 disorder
       Region 6q0w A 1022-1111 order
       Region 6q0w A 1112-1123 disorder
       Region 6q0w A 1124-1140 order
Seq 1-395,706-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 6bnb A Reference
       Region 6bnb A 1-287 order
       Region 6bnb A 288-294 disorder
       Region 6bnb A 295-393 order
       Region 6bnb A 394-395 disorder
       Region 6bnb A 706-708 disorder
       Region 6bnb A 709-770 order
       Region 6bnb A 771-781 disorder
       Region 6bnb A 782-1015 order
       Region 6bnb A 1016-1020 disorder
       Region 6bnb A 1021-1111 order
       Region 6bnb A 1112-1124 disorder
       Region 6bnb A 1125-1140 order
Seq 1-395,706-1140 Hetero pentamer : Q66K64,Q9BW61
 Evidence X-RAY 6ue5 B Reference
       Region 6ue5 B 1-1 disorder
       Region 6ue5 B 2-395 order
       Region 6ue5 B 706-708 disorder
       Region 6ue5 B 709-773 order
       Region 6ue5 B 774-779 disorder
       Region 6ue5 B 780-1015 order
       Region 6ue5 B 1016-1022 disorder
       Region 6ue5 B 1023-1110 order
       Region 6ue5 B 1111-1124 disorder
       Region 6ue5 B 1125-1140 order
Seq 1-1140 Hetero dimer : F5HF44
 Evidence X-RAY 7ukn A Reference
       Region 7ukn A 1-1 disorder
       Region 7ukn A 2-46 order
       Region 7ukn A 47-47 disorder
       Region 7ukn A 48-288 order
       Region 7ukn A 289-294 disorder
       Region 7ukn A 295-414 order
       Region 7ukn A 415-417 disorder
       Region 7ukn A 418-438 order
       Region 7ukn A 439-455 disorder
       Region 7ukn A 456-476 order
       Region 7ukn A 477-491 disorder
       Region 7ukn A 492-545 order
       Region 7ukn A 546-552 disorder
       Region 7ukn A 553-684 order
       Region 7ukn A 685-685 disorder
       Region 7ukn A 686-746 order
       Region 7ukn A 747-748 disorder
       Region 7ukn A 749-772 order
       Region 7ukn A 773-782 disorder
       Region 7ukn A 783-1015 order
       Region 7ukn A 1016-1022 disorder
       Region 7ukn A 1023-1111 order
       Region 7ukn A 1112-1122 disorder
       Region 7ukn A 1123-1140 order
Seq 1-395,709-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 5fqd A Reference
       Region 5fqd A 1-287 order
       Region 5fqd A 288-294 disorder
       Region 5fqd A 295-393 order
       Region 5fqd A 394-395 disorder
       Region 5fqd A 709-770 order
       Region 5fqd A 771-781 disorder
       Region 5fqd A 782-1015 order
       Region 5fqd A 1016-1020 disorder
       Region 5fqd A 1021-1111 order
       Region 5fqd A 1112-1124 disorder
       Region 5fqd A 1125-1140 order
Seq 1-1140 Hetero tetramer : Q13620,Q2YDS1
 Evidence X-RAY 4a0l A Reference
       Region 4a0l A 1-290 order
       Region 4a0l A 291-294 disorder
       Region 4a0l A 295-771 order
       Region 4a0l A 772-783 disorder
       Region 4a0l A 784-1015 order
       Region 4a0l A 1016-1022 disorder
       Region 4a0l A 1023-1111 order
       Region 4a0l A 1112-1123 disorder
       Region 4a0l A 1124-1140 order
 Evidence X-RAY 4a0l C Reference
       Region 4a0l C 1-290 order
       Region 4a0l C 291-294 disorder
       Region 4a0l C 295-771 order
       Region 4a0l C 772-783 disorder
       Region 4a0l C 784-1015 order
       Region 4a0l C 1016-1022 disorder
       Region 4a0l C 1023-1111 order
       Region 4a0l C 1112-1123 disorder
       Region 4a0l C 1124-1140 order
Seq 1-395,706-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 6bn8 A Reference
       Region 6bn8 A 1-287 order
       Region 6bn8 A 288-294 disorder
       Region 6bn8 A 295-393 order
       Region 6bn8 A 394-395 disorder
       Region 6bn8 A 706-708 disorder
       Region 6bn8 A 709-769 order
       Region 6bn8 A 770-775 disorder
       Region 6bn8 A 776-1015 order
       Region 6bn8 A 1016-1021 disorder
       Region 6bn8 A 1022-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bug G Reference
       Region 8bug G 1-394 order
       Region 8bug G 395-395 disorder
       Region 8bug G 709-1140 order
 Evidence X-RAY 8bug D Reference
       Region 8bug D 1-394 order
       Region 8bug D 395-395 disorder
       Region 8bug D 709-1140 order
 Evidence X-RAY 8bug A Reference
       Region 8bug A 1-393 order
       Region 8bug A 394-395 disorder
       Region 8bug A 709-1140 order
Seq 1-1140 Hetero dimer : IID00854Complex
 Evidence X-RAY 3i7l A Reference
       Region 3i7l A 1-773 order
       Region 3i7l A 774-782 disorder
       Region 3i7l A 783-1015 order
       Region 3i7l A 1016-1022 disorder
       Region 3i7l A 1023-1111 order
       Region 3i7l A 1112-1121 disorder
       Region 3i7l A 1122-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bur G Reference
       Region 8bur G 1-394 order
       Region 8bur G 395-395 disorder
       Region 8bur G 709-1140 order
 Evidence X-RAY 8bur D Reference
       Region 8bur D 1-393 order
       Region 8bur D 394-395 disorder
       Region 8bur D 709-1140 order
 Evidence X-RAY 8bur A Reference
       Region 8bur A 1-394 order
       Region 8bur A 395-395 disorder
       Region 8bur A 709-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu6 G Reference
       Region 8bu6 G 1-393 order
       Region 8bu6 G 394-395 disorder
       Region 8bu6 G 709-1140 order
 Evidence X-RAY 8bu6 D Reference
       Region 8bu6 D 1-394 order
       Region 8bu6 D 395-395 disorder
       Region 8bu6 D 709-1140 order
 Evidence X-RAY 8bu6 A Reference
       Region 8bu6 A 1-394 order
       Region 8bu6 A 395-395 disorder
       Region 8bu6 A 709-1140 order
Seq 1-1140 Hetero tetramer : IID00514Complex,Q2YDS1
 Evidence X-RAY 4a0k C Reference
       Region 4a0k C 1-290 order
       Region 4a0k C 291-294 disorder
       Region 4a0k C 295-771 order
       Region 4a0k C 772-783 disorder
       Region 4a0k C 784-1015 order
       Region 4a0k C 1016-1022 disorder
       Region 4a0k C 1023-1111 order
       Region 4a0k C 1112-1123 disorder
       Region 4a0k C 1124-1140 order
Seq 1-1140 Hetero dimer : Q8N5D0
 Evidence X-RAY 3i7n A Reference
       Region 3i7n A 1-773 order
       Region 3i7n A 774-782 disorder
       Region 3i7n A 783-1015 order
       Region 3i7n A 1016-1022 disorder
       Region 3i7n A 1023-1111 order
       Region 3i7n A 1112-1121 disorder
       Region 3i7n A 1122-1140 order
Seq 1-395,709-1140 Hetero dodecamer : IID00695Complex,Q9NYV4
 Evidence X-RAY 8bu4 G Reference
       Region 8bu4 G 1-394 order
       Region 8bu4 G 395-395 disorder
       Region 8bu4 G 709-1140 order
 Evidence X-RAY 8bu4 D Reference
       Region 8bu4 D 1-394 order
       Region 8bu4 D 395-395 disorder
       Region 8bu4 D 709-1140 order
 Evidence X-RAY 8bu4 A Reference
       Region 8bu4 A 1-393 order
       Region 8bu4 A 394-395 disorder
       Region 8bu4 A 709-1140 order
Seq 1-395,706-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 6boy A Reference
       Region 6boy A 1-287 order
       Region 6boy A 288-294 disorder
       Region 6boy A 295-393 order
       Region 6boy A 394-395 disorder
       Region 6boy A 706-708 disorder
       Region 6boy A 709-770 order
       Region 6boy A 771-775 disorder
       Region 6boy A 776-1015 order
       Region 6boy A 1016-1020 disorder
       Region 6boy A 1021-1140 order
Seq 1-395,709-1140 Hetero tetramer : Q96SW2
 Evidence X-RAY 5fqd D Reference
       Region 5fqd D 1-337 order
       Region 5fqd D 338-344 disorder
       Region 5fqd D 345-393 order
       Region 5fqd D 394-395 disorder
       Region 5fqd D 709-770 order
       Region 5fqd D 771-779 disorder
       Region 5fqd D 780-979 order
       Region 5fqd D 980-986 disorder
       Region 5fqd D 987-1112 order
       Region 5fqd D 1113-1124 disorder
       Region 5fqd D 1125-1140 order
Seq 391-709 Monomer :
 Evidence X-RAY 2b5n A Reference
       Region 2b5n A 391-391 disorder
       Region 2b5n A 392-546 order
       Region 2b5n A 547-550 disorder
       Region 2b5n A 551-707 order
       Region 2b5n A 708-709 disorder
 Evidence X-RAY 2b5n B Reference
       Region 2b5n B 391-707 order
       Region 2b5n B 708-709 disorder
 Evidence X-RAY 2b5n C Reference
       Region 2b5n C 391-706 order
       Region 2b5n C 707-709 disorder
 Evidence X-RAY 2b5n D Reference
       Region 2b5n D 391-707 order
       Region 2b5n D 708-709 disorder
Seqphosphorylation
    1125-1125 Phosphothreonine
Seqacetylation
    2-2 N-acetylserine
    1067-1067 N6-acetyllysine
 
Prediction
NeProc
Disorder 748-782
Order 1-747,783-981,988-1140
ProS 748-757,779-782
AlphaFold
Disorder 370-371,549-549,644-645,662-665,706-709,770-783,1014-1023,1116-1117
Order 1-369,372-548,550-643,646-661,666-705,710-769,784-1013,1024-1115,1118-1140
Pfam Hmmer
PF03178 785-1069 1.7e-160
SEG 755-775
Function
Function in SwissProt
Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively (PubMed:15448697, PubMed:14739464, PubMed:16260596, PubMed:16482215, PubMed:17079684, PubMed:16407242, PubMed:16407252, PubMed:16940174). Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (PubMed:15448697, PubMed:16260596, PubMed:16407242, PubMed:16940174). The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches (PubMed:15448697, PubMed:16260596, PubMed:16407242, PubMed:16940174). Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:14739464, PubMed:16407252, PubMed:16482215, PubMed:17079684, PubMed:25043012, PubMed:25108355, PubMed:18332868, PubMed:18381890, PubMed:19966799, PubMed:22118460, PubMed:28886238). The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1 (PubMed:14739464, PubMed:16407252, PubMed:16482215, PubMed:17079684, PubMed:25043012, PubMed:25108355, PubMed:18332868, PubMed:18381890, PubMed:19966799, PubMed:22118460). DCX(DDB2) (also known as DDB1-CUL4-ROC1, CUL4-DDB-ROC1 and CUL4-DDB-RBX1) may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage (PubMed:16678110, PubMed:17041588, PubMed:16473935, PubMed:18593899). The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair (PubMed:16678110, PubMed:17041588, PubMed:16473935, PubMed:18593899). DCX(DDB2) also ubiquitinates XPC, which may enhance DNA-binding by XPC and promote NER (PubMed:15882621). DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication (PubMed:17041588). DCX(ERCC8) (the CSA complex) plays a role in transcription-coupled repair (TCR) (PubMed:12732143). The DDB1-CUL4A-DTL E3 ligase complex regulates the circadian clock function by mediating the ubiquitination and degradation of CRY1 (PubMed:26431207). DDB1-mediated CRY1 degradation promotes FOXO1 protein stability and FOXO1-mediated gluconeogenesis in the liver (By similarity). By acting on TET dioxygenses, essential for oocyte maintenance at the primordial follicle stage, hence essential for female fertility (By similarity). Maternal factor required for proper zygotic genome activation and genome reprogramming (By similarity).
Biological Process
See also
Diagram with PDB data
XPA/ERCC1Solution structure of a ERCC1-XPA heterodimer
XPC/CETN2Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein