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IID00845
 UniprotQ6TGC4
ProteinProtein-arginine deiminase type-6
GenePADI6
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
694
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-13 Hetero tetramer : IID00301Complex
 Evidence X-RAY 4dau B Reference
       Region 4dau B 1-7 disorder
       Region 4dau B 8-13 order
Seq 441-449 Hetero tetramer : IID00301Complex
 Evidence X-RAY 4dat B Reference
       Region 4dat B 441-442 disorder
       Region 4dat B 443-448 order
       Region 4dat B 449-449 disorder
Seqphosphorylation
    10-10 Phosphoserine
    446-446 Phosphoserine
 
Prediction
NeProc
Disorder 4-7
Order 1-3,8-65,72-282,287-694
ProS 4-7
AlphaFold
Disorder 1-12,68-71,79-80,164-184,228-230,249-249,323-324,347-354,381-396,407-411,493-496,597-598,668-675
Order 13-67,72-78,81-163,185-227,231-248,250-322,325-346,355-380,397-406,412-492,497-596,599-667,676-694
Pfam Hmmer
PF08526 9-120 3.4e-29
PF08527 122-281 5.1e-45
PF03068 287-694 2.8e-182
SEG 641-654
Function
Function in SwissProt
Catalyzes the deimination of arginine residues of proteins (By similarity). In oocytes, is released during cortical reaction and plays a role in preimplantation cleavage and early embryonic development (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo (PubMed:27545678).