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IID00854
 UniprotQ92466
ProteinDNA damage-binding protein 2
GeneDDB2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
427
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-427 Hetero dimer : IID00840Complex
 Evidence X-RAY 3ei4 B Reference
       Region 3ei4 B 10-53 disorder
       Region 3ei4 B 54-421 order
       Region 3ei4 B 422-427 disorder
 Evidence X-RAY 3ei4 D Reference
       Region 3ei4 D 10-53 disorder
       Region 3ei4 D 54-421 order
       Region 3ei4 D 422-427 disorder
 Evidence X-RAY 3ei4 F Reference
       Region 3ei4 F 10-53 disorder
       Region 3ei4 F 54-421 order
       Region 3ei4 F 422-427 disorder
 Evidence X-RAY 4e54 B Reference
       Region 4e54 B 2-19 disorder
       Region 4e54 B 20-421 order
       Region 4e54 B 422-427 disorder
 Evidence X-RAY 4e5z B Reference
       Region 4e5z B 2-19 disorder
       Region 4e5z B 20-420 order
       Region 4e5z B 421-427 disorder
Seq 68-81 Hetero dimer : IID00840Complex
 Evidence X-RAY 3i7l B Reference
       Region 3i7l B 68-81 order
SeqProS verified 20-53 Hetero dimer : IID00840Complex
       Region 4e54 B 20-421 order
       Region 4e5z B 20-420 order
       Region 3ei4 B 10-53 disorder
Seqphosphorylation
    24-24 Phosphoserine
    26-26 Phosphoserine
Seqacetylation
    35-35 N6-acetyllysine
    77-77 N6-acetyllysine
 
Prediction
NeProc
Disorder 1-60
Order 61-427
ProS 17-60
AlphaFold
Disorder 1-67,364-364,422-427
Order 68-363,365-421
Pfam Hmmer
PF00400 232-271 5.6e-07
Function
Function in SwissProt
Inhibits UV-damaged DNA repair.
Biological Process
See also
Diagram with PDB data
XPA/ERCC1Solution structure of a ERCC1-XPA heterodimer
XPC/CETN2Solution structure of the C-terminal domain (T94-Y172) of the human centrin 2 in complex with a 17 residues peptide (P1-XPC) from xeroderma pigmentosum group C protein