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IID00879
 UniprotQ9H9L4
ProteinKAT8 regulatory NSL complex subunit 2
GeneKANSL2
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
492
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 406-417 Hetero trimer : IID00377Complex
 Evidence X-RAY 4cy2 C Reference
       Region 4cy2 C 406-407 disorder
       Region 4cy2 C 408-416 order
       Region 4cy2 C 417-417 disorder
SeqProS predicted 408-416 This region is predicted to be disordered by AlphaFold (pLDDT <68.5) and NeProc. Hetero trimer : IID00377Complex
       Region 4cy2 C 408-416 order
Seqphosphorylation
    175-175 Phosphoserine
    172-172 Phosphoserine
    168-168 Phosphoserine
    149-149 Phosphoserine
    147-147 Phosphoserine
    131-131 Phosphothreonine
 
Prediction
NeProc
Disorder 1-26,94-174,243-279,288-298,373-492
Order 27-93,175-242,280-287,299-372
ProS 1-18,94-99,112-174,243-279,416-450,486-492
AlphaFold
Disorder 1-25,103-156,162-178,238-247,287-298,369-492
Order 26-102,157-161,179-237,248-286,299-368
Function
Function in SwissProt
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.