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IID00890
 UniprotQ9UK41
ProteinVacuolar protein sorting-associated protein 28 homolog
GeneVPS28
OrganismHomo sapiens
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
221
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-122 Hetero 24mer : IID00861Complex,IID00868Complex,IID00878Complex
 Evidence X-RAY 6vme Y Reference
       Region 6vme Y 1-18 disorder
       Region 6vme Y 19-118 order
       Region 6vme Y 119-122 disorder
 Evidence X-RAY 6vme X Reference
       Region 6vme X 1-17 disorder
       Region 6vme X 18-118 order
       Region 6vme X 119-122 disorder
 Evidence X-RAY 6vme W Reference
       Region 6vme W 1-13 disorder
       Region 6vme W 14-118 order
       Region 6vme W 119-122 disorder
 Evidence X-RAY 6vme V Reference
       Region 6vme V 1-14 disorder
       Region 6vme V 15-118 order
       Region 6vme V 119-122 disorder
 Evidence X-RAY 6vme U Reference
       Region 6vme U 1-16 disorder
       Region 6vme U 17-118 order
       Region 6vme U 119-122 disorder
 Evidence X-RAY 6vme E Reference
       Region 6vme E 1-15 disorder
       Region 6vme E 16-117 order
       Region 6vme E 118-122 disorder
 
Prediction
NeProc
Disorder 1-17
Order 18-120,126-221
ProS 1-4
AlphaFold
Disorder 1-14,119-123
Order 15-118,124-221
Pfam Hmmer
PF03997 39-220 8.8e-135
SEG 4-15
Function
Function in SwissProt
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
Biological Process
See also
Diagram with PDB data
VPS36/SNF8/VPS25/VPS25Integrated structural and functional model of the human ESCRT-II complex
CHMP6/VPS25Crystal structure of the human VPS25-VPS20 subcomplex
TSG101/HGSCrystal Structure of the Tsg101 UEV domain in complex with a human HRS PSAP peptide