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IID50003  Cadherin-1 (Mus musculus) P09803
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
884
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 156-300 Monomer :
 Evidence NMR 1suh A Reference
       Region 1suh A 156-156 disorder
       Region 1suh A 157-260 order
       Region 1suh A 258-260 high_rmsd
       Region 1suh A 261-300 disorder
Seq 156-380 Homo dimer :
 Evidence X-RAY 1edh A Reference
       Region 1edh A 156-158 disorder
       Region 1edh A 159-369 order
       Region 1edh A 370-380 disorder
 Evidence X-RAY 1edh B Reference
       Region 1edh B 156-158 disorder
       Region 1edh B 159-369 order
       Region 1edh B 370-380 disorder
 Evidence X-RAY 1ff5 A Reference
       Region 1ff5 A 157-374 order
 Evidence X-RAY 1ff5 B Reference
       Region 1ff5 B 157-374 order
 Evidence X-RAY 3lne A Reference
       Region 3lne A 157-369 order
 Evidence X-RAY 3lng A Reference
       Region 3lng A 157-157 disorder
       Region 3lng A 158-369 order
 Evidence X-RAY 3lng B Reference
       Region 3lng B 157-157 disorder
       Region 3lng B 158-369 order
 Evidence X-RAY 3lnh A Reference
       Region 3lnh A 157-160 disorder
       Region 3lnh A 161-369 order
 Evidence X-RAY 3lnh B Reference
       Region 3lnh B 157-160 disorder
       Region 3lnh B 161-369 order
 Evidence X-RAY 3lni A Reference
       Region 3lni A 157-184 order
       Region 3lni A 185-186 disorder
       Region 3lni A 187-369 order
 Evidence X-RAY 3lni B Reference
       Region 3lni B 157-157 disorder
       Region 3lni B 158-182 order
       Region 3lni B 183-187 disorder
       Region 3lni B 188-369 order
 Evidence X-RAY 3q2l A Reference
       Region 3q2l A 157-369 order
 Evidence X-RAY 3q2l B Reference
       Region 3q2l B 157-369 order
 Evidence X-RAY 3q2n A Reference
       Region 3q2n A 157-369 order
 Evidence X-RAY 3q2n B Reference
       Region 3q2n B 157-369 order
 Evidence X-RAY 3qrb A Reference
       Region 3qrb A 157-369 order
 Evidence X-RAY 3qrb B Reference
       Region 3qrb B 157-369 order
 Evidence X-RAY 2qvf B Reference
       Region 2qvf B 157-369 order
Seq 157-369 Hetero pentamer : A5HZZ4,A5HZZ5,A5HZZ6
 Evidence X-RAY 4qd2 E Reference
       Region 4qd2 E 157-157 disorder
       Region 4qd2 E 158-369 order
 Evidence X-RAY 4qd2 J Reference
       Region 4qd2 J 157-157 disorder
       Region 4qd2 J 158-369 order
Seq 157-369 Monomer :
 Evidence X-RAY 3lnf A Reference
       Region 3lnf A 157-158 disorder
       Region 3lnf A 159-369 order
 Evidence X-RAY 3lnf B Reference
       Region 3lnf B 157-160 disorder
       Region 3lnf B 161-183 order
       Region 3lnf B 184-187 disorder
       Region 3lnf B 188-369 order
 Evidence X-RAY 1q1p A Reference
       Region 1q1p A 158-369 order
Seq 157-700 Homo dimer :
 Evidence X-RAY 3q2v A Reference
       Region 3q2v A 157-659 order
       Region 3q2v A 660-663 disorder
       Region 3q2v A 664-692 order
       Region 3q2v A 693-700 disorder
 Evidence X-RAY 3q2v B Reference
       Region 3q2v B 157-590 order
       Region 3q2v B 591-617 disorder
       Region 3q2v B 618-623 order
       Region 3q2v B 624-700 disorder
Seq 158-256 Hetero dimer : P0DJM0
 Evidence X-RAY 2omw B Reference
       Region 2omw B 158-256 order
Seq 734-884 Hetero tetramer : IID50011Complex
 Evidence X-RAY 1i7w B Reference
       Region 1i7w B 734-816 disorder
       Region 1i7w B 817-850 order
       Region 1i7w B 851-861 disorder
       Region 1i7w B 862-878 order
       Region 1i7w B 879-884 disorder
 Evidence X-RAY 1i7w D Reference
       Region 1i7w D 734-787 disorder
       Region 1i7w D 788-791 order
       Region 1i7w D 792-812 disorder
       Region 1i7w D 813-850 order
       Region 1i7w D 851-860 disorder
       Region 1i7w D 861-878 order
       Region 1i7w D 879-884 disorder
Seq 734-884 Hetero trimer : IID50011Complex
 Evidence X-RAY 1i7x B Reference
       Region 1i7x B 734-783 disorder
       Region 1i7x B 784-840 order
       Region 1i7x B 841-884 disorder
 Evidence X-RAY 1i7x D Reference
       Region 1i7x D 734-785 disorder
       Region 1i7x D 786-791 order
       Region 1i7x D 792-809 disorder
       Region 1i7x D 810-840 order
       Region 1i7x D 841-853 disorder
       Region 1i7x D 854-879 order
       Region 1i7x D 880-884 disorder
Seqdisorder 773-884
 Evidence NMR Reference
       Region 773-884 disorder
Seq 778-884 Hetero tetramer : IID00298Complex
 Evidence X-RAY 3ifq C Reference
       Region 3ifq C 778-783 disorder
       Region 3ifq C 784-852 order
       Region 3ifq C 853-857 disorder
       Region 3ifq C 858-881 order
       Region 3ifq C 882-884 disorder
 Evidence X-RAY 3ifq D Reference
       Region 3ifq D 778-783 disorder
       Region 3ifq D 784-851 order
       Region 3ifq D 852-854 disorder
       Region 3ifq D 855-877 order
       Region 3ifq D 878-884 disorder
SeqProS verified 784-840,854-879 Hetero trimer : IID50011Complex
       Region 1i7x B 784-840 order
       Region 1i7x D 786-791 order
       Region 1i7x D 810-840 order
       Region 1i7x D 854-879 order
       Region 773-884 disorder
SeqProS verified 784-852,855-881 Hetero tetramer : IID00298Complex
       Region 3ifq C 784-852 order
       Region 3ifq C 858-881 order
       Region 3ifq D 784-851 order
       Region 3ifq D 855-877 order
       Region 773-884 disorder
SeqProS verified 788-791,813-850,861-878 Hetero tetramer : IID50011Complex
       Region 1i7w B 817-850 order
       Region 1i7w B 862-878 order
       Region 1i7w D 788-791 order
       Region 1i7w D 813-850 order
       Region 1i7w D 861-878 order
       Region 773-884 disorder
Seqphosphorylation
    755-755 Phosphotyrosine; by SRC
    756-756 Phosphotyrosine; by SRC
    757-757 Phosphotyrosine; by SRC
    772-772 Phosphoserine
    795-795 Phosphoserine
    840-840 Phosphoserine
    842-842 Phosphoserine
    848-848 Phosphoserine
 
Prediction
DICHOT
Disorder 1-29,112-156,693-710,734-783,879-884
Known Domain 30-111,157-692,711-733,784-878
SCOPe RPS-Blast
     1op4A 26-156 4e-29 b.1.6.1 C-cadherin ectodomain
     2yqgA1 154-267 8e-48 b.1.6.0 automated matches
     4zmyA2 258-369 2e-49 b.1.6.0 automated matches
     1l3wA3 371-482 2e-38 b.1.6.1 C-cadherin ectodomain
     1l3wA4 483-590 3e-34 b.1.6.1 C-cadherin ectodomain
     1l3wA5 591-697 1e-28 b.1.6.1 C-cadherin ectodomain
SCOP Hmmer
     1op4A_ 29-175 1.2e-22 b.1.6.1 C-cadherin ectodo...
     1l3wA5 162-264 2.6e-16 b.1.6.1 C-cadherin ectod...
     1op4A_ 252-390 1.3e-34 b.1.6.1 C-cadherin ectod...
     1l3wA3 370-482 2.8e-22 b.1.6.1 C-cadherin ectod...
     1op4A_ 477-604 1.9e-24 b.1.6.1 C-cadherin ectod...
     1l3wA5 591-691 3.9e-15 b.1.6.1 C-cadherin ectod...
Pfam RPS-Blast
     PF08758 37-118 1e-14 Cadherin prodomain like
     PF00028 269-367 5e-04 Cadherin domain
     PF01049 735-880 1e-31 Cadherin cytoplasmic region
Pfam Hmmer
    PF08758 30-118 8.6e-33 Cadherin prodomain like
    PF00028 163-255 5.5e-17 Cadherin domain
    PF00028 270-367 5.7e-25 Cadherin domain
    PF00028 382-479 4.7e-18 Cadherin domain
    PF00028 494-584 2.4e-16 Cadherin domain
    PF00028 605-688 1.8e-10 Cadherin domain
    PF01049 736-880 2.1e-52 Cadherin cytoplasmic regio...