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IID50009  Importin subunit alpha-1 (Mus musculus) P52293
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
529
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 1-70
 Evidence CD Reference
       Region 1-70 disorder
Seq 1-529 Monomer :
 Evidence X-RAY 1ial A Reference
       Region 1ial A 44-54 order
       Region 1ial A 55-69 disorder
       Region 1ial A 70-496 order
 Evidence X-RAY 3tpo A Reference
       Region 3tpo A 1-43 disorder
       Region 3tpo A 44-54 order
       Region 3tpo A 55-69 disorder
       Region 3tpo A 70-496 order
       Region 3tpo A 497-529 disorder
 Evidence X-RAY 4u54 A Reference
       Region 4u54 A 74-498 order
 Evidence X-RAY 4u58 A Reference
       Region 4u58 A 72-497 order
 Evidence X-RAY 4u5s A Reference
       Region 4u5s A 72-497 order
 Evidence X-RAY 4u5u A Reference
       Region 4u5u A 72-497 order
 Evidence X-RAY 4u5v A Reference
       Region 4u5v A 72-497 order
 Evidence X-RAY 4u5l A Reference
       Region 4u5l A 72-497 order
 Evidence X-RAY 4u5n A Reference
       Region 4u5n A 72-497 order
 Evidence X-RAY 4u5o A Reference
       Region 4u5o A 72-497 order
Seq 2-529 Hetero trimer : D3YRZ5
 Evidence X-RAY 5huy C Reference
       Region 5huy C 2-74 disorder
       Region 5huy C 75-497 order
       Region 5huy C 498-529 disorder
Seq 2-529 Hetero trimer : P04295
 Evidence X-RAY 5huw C Reference
       Region 5huw C 2-74 disorder
       Region 5huw C 75-497 order
       Region 5huw C 498-529 disorder
Seq 2-529 Hetero trimer :
 Evidence X-RAY 5v5p C Reference
       Region 5v5p C 2-74 disorder
       Region 5v5p C 75-497 order
       Region 5v5p C 498-529 disorder
Seq 2-529 Hetero trimer :
 Evidence X-RAY 5v5o C Reference
       Region 5v5o C 2-74 disorder
       Region 5v5o C 75-497 order
       Region 5v5o C 498-529 disorder
Seq 44-54,70-529 Hetero trimer :
 Evidence X-RAY 1iq1 A Reference
       Region 1iq1 A 44-46 disorder
       Region 1iq1 A 47-53 order
       Region 1iq1 A 54-54 disorder
 Evidence X-RAY 1iq1 B Reference
       Region 1iq1 B 44-44 disorder
       Region 1iq1 B 45-53 order
       Region 1iq1 B 54-54 disorder
 Evidence X-RAY 1iq1 C Reference
       Region 1iq1 C 70-71 disorder
       Region 1iq1 C 72-497 order
       Region 1iq1 C 498-529 disorder
Seq 69-529 Hetero dimer : P31345
 Evidence X-RAY 4uaf B Reference
       Region 4uaf B 69-71 disorder
       Region 4uaf B 72-496 order
       Region 4uaf B 497-529 disorder
Seq 70-496 Hetero dimer : IID00020Complex
 Evidence X-RAY 3btr C Reference
       Region 3btr C 70-496 order
Seq 70-497 Hetero dimer : Q14980
 Evidence X-RAY 5gxw A Reference
       Region 5gxw A 70-497 order
Seq 70-497 Hetero dimer : IID00006Complex
 Evidence X-RAY 1y2a C Reference
       Region 1y2a C 70-74 disorder
       Region 1y2a C 75-497 order
Seq 70-528 Hetero trimer : P33316
 Evidence X-RAY 4mz5 E Reference
       Region 4mz5 E 70-70 disorder
       Region 4mz5 E 71-497 order
       Region 4mz5 E 498-528 disorder
 Evidence X-RAY 4mz6 E Reference
       Region 4mz6 E 70-71 disorder
       Region 4mz6 E 72-497 order
       Region 4mz6 E 498-528 disorder
Seq 70-528 Hetero trimer :
 Evidence X-RAY 5umz B Reference
       Region 5umz B 70-71 disorder
       Region 5umz B 72-497 order
       Region 5umz B 498-528 disorder
Seq 70-528 Hetero dimer : Q68SX0
 Evidence X-RAY 4htv A Reference
       Region 4htv A 70-70 disorder
       Region 4htv A 71-497 order
       Region 4htv A 498-528 disorder
Seq 70-529 Hetero dimer : IID50001Complex
 Evidence X-RAY 1ejy I Reference
       Region 1ejy I 70-71 disorder
       Region 1ejy I 72-497 order
       Region 1ejy I 498-529 disorder
 Evidence X-RAY 3ul1 B Reference
       Region 3ul1 B 70-71 disorder
       Region 3ul1 B 72-497 order
       Region 3ul1 B 498-529 disorder
Seq 70-529 Hetero dimer : P54278
 Evidence X-RAY 5u5r A Reference
       Region 5u5r A 70-71 disorder
       Region 5u5r A 72-497 order
       Region 5u5r A 498-529 disorder
Seq 70-529 Hetero dimer :
 Evidence X-RAY 3ukx B Reference
       Region 3ukx B 70-71 disorder
       Region 3ukx B 72-497 order
       Region 3ukx B 498-529 disorder
Seq 70-529 Hetero trimer : IID90004Complex
 Evidence X-RAY 5wum A Reference
       Region 5wum A 70-71 disorder
       Region 5wum A 72-497 order
       Region 5wum A 498-529 disorder
 Evidence X-RAY 5wun A Reference
       Region 5wun A 70-71 disorder
       Region 5wun A 72-497 order
       Region 5wun A 498-529 disorder
Seq 70-529 Hetero dimer : IID50002Complex
 Evidence X-RAY 1pjn B Reference
       Region 1pjn B 70-71 disorder
       Region 1pjn B 72-497 order
       Region 1pjn B 498-529 disorder
Seq 70-529 Hetero dimer :
 Evidence X-RAY 5klr B Reference
       Region 5klr B 70-71 disorder
       Region 5klr B 72-497 order
       Region 5klr B 498-529 disorder
Seq 70-529 Hetero dimer : IID00023Complex
 Evidence X-RAY 3rzx A Reference
       Region 3rzx A 70-70 disorder
       Region 3rzx A 71-497 order
       Region 3rzx A 498-529 disorder
Seq 70-529 Hetero trimer : P40692
 Evidence X-RAY 5u5p A Reference
       Region 5u5p A 70-71 disorder
       Region 5u5p A 72-497 order
       Region 5u5p A 498-529 disorder
Seq 70-529 Hetero dimer :
 Evidence X-RAY 5klt B Reference
       Region 5klt B 70-71 disorder
       Region 5klt B 72-497 order
       Region 5klt B 498-529 disorder
Seq 70-529 Hetero dimer : Q9UGN5
 Evidence X-RAY 5d5k C Reference
       Region 5d5k C 70-72 disorder
       Region 5d5k C 73-496 order
       Region 5d5k C 497-529 disorder
Seq 70-529 Hetero dimer : P52591
 Evidence X-RAY 4yi0 C Reference
       Region 4yi0 C 70-72 disorder
       Region 4yi0 C 73-497 order
       Region 4yi0 C 498-529 disorder
Seq 70-529 Hetero dimer :
 Evidence X-RAY 3ukw B Reference
       Region 3ukw B 70-71 disorder
       Region 3ukw B 72-497 order
       Region 3ukw B 498-529 disorder
Seq 70-529 Hetero dimer : IID00017Complex
 Evidence X-RAY 1pjm B Reference
       Region 1pjm B 70-70 disorder
       Region 1pjm B 71-497 order
       Region 1pjm B 498-529 disorder
Seq 70-529 Hetero dimer :
 Evidence X-RAY 4ba3 A Reference
       Region 4ba3 A 70-496 order
       Region 4ba3 A 497-529 disorder
Seq 70-529 Hetero dimer : Q9NRQ2
 Evidence X-RAY 3q5u A Reference
       Region 3q5u A 70-74 disorder
       Region 3q5u A 75-497 order
       Region 3q5u A 498-529 disorder
Seq 70-529 Hetero dimer : IID50179Complex
 Evidence X-RAY 3ukz B Reference
       Region 3ukz B 70-70 disorder
       Region 3ukz B 71-497 order
       Region 3ukz B 498-529 disorder
 Evidence X-RAY 3ul0 B Reference
       Region 3ul0 B 70-70 disorder
       Region 3ul0 B 71-496 order
       Region 3ul0 B 497-529 disorder
Seq 70-529 Hetero dimer : IID00044Complex
 Evidence X-RAY 3uvu A Reference
       Region 3uvu A 70-71 disorder
       Region 3uvu A 72-496 order
       Region 3uvu A 497-529 disorder
Seq 70-529 Hetero dimer : IID00024Complex
 Evidence X-RAY 3rz9 A Reference
       Region 3rz9 A 70-71 disorder
       Region 3rz9 A 72-496 order
       Region 3rz9 A 497-529 disorder
Seq 70-529 Hetero trimer : P28715
 Evidence X-RAY 5ekf A Reference
       Region 5ekf A 70-71 disorder
       Region 5ekf A 72-496 order
       Region 5ekf A 497-529 disorder
Seq 70-529 Hetero dimer : IID50172Complex
 Evidence X-RAY 3uky B Reference
       Region 3uky B 70-70 disorder
       Region 3uky B 71-497 order
       Region 3uky B 498-529 disorder
Seq 70-529 Hetero dimer : Q8AZK7
 Evidence X-RAY 5x8n A Reference
       Region 5x8n A 70-72 disorder
       Region 5x8n A 73-497 order
       Region 5x8n A 498-529 disorder
Seq 70-529 Hetero hexamer : Q73369
 Evidence X-RAY 5b56 A Reference
       Region 5b56 A 70-498 order
       Region 5b56 A 499-529 disorder
 Evidence X-RAY 5b56 B Reference
       Region 5b56 B 70-70 disorder
       Region 5b56 B 71-502 order
       Region 5b56 B 503-529 disorder
Seq 70-529 Hetero dimer : P18887
 Evidence X-RAY 5e6q B Reference
       Region 5e6q B 70-71 disorder
       Region 5e6q B 72-496 order
       Region 5e6q B 497-529 disorder
Seq 70-529 Hetero dimer : Q9Y696
 Evidence X-RAY 3oqs A Reference
       Region 3oqs A 70-71 disorder
       Region 3oqs A 72-496 order
       Region 3oqs A 497-529 disorder
Seq 70-529 Hetero dimer : P04326
 Evidence X-RAY 5svz A Reference
       Region 5svz A 70-71 disorder
       Region 5svz A 72-497 order
       Region 5svz A 498-529 disorder
Seq 70-529 Hetero trimer : IID90002Complex
 Evidence X-RAY 1ejl I Reference
       Region 1ejl I 70-71 disorder
       Region 1ejl I 72-497 order
       Region 1ejl I 498-529 disorder
 Evidence X-RAY 1q1s C Reference
       Region 1q1s C 70-497 order
       Region 1q1s C 498-529 disorder
 Evidence X-RAY 1q1t C Reference
       Region 1q1t C 70-496 order
       Region 1q1t C 497-529 disorder
Seq 70-529 Hetero dimer : Q6NUF4
 Evidence X-RAY 3knd A Reference
       Region 3knd A 70-497 order
       Region 3knd A 498-529 disorder
Seq 70-529 Hetero dimer : P28715
 Evidence X-RAY 5ekg A Reference
       Region 5ekg A 70-71 disorder
       Region 5ekg A 72-496 order
       Region 5ekg A 497-529 disorder
Seq 70-529 Hetero dimer : P21827
 Evidence X-RAY 4oih A Reference
       Region 4oih A 70-71 disorder
       Region 4oih A 72-497 order
       Region 4oih A 498-529 disorder
Seq 71-496 Hetero dimer : P09592
 Evidence X-RAY 3ve6 A Reference
       Region 3ve6 A 71-496 order
Seq 71-497 Hetero dimer : P12823
 Evidence X-RAY 5hhg E Reference
       Region 5hhg E 71-497 order
Seq 71-497 Hetero trimer :
 Evidence X-RAY 3l3q A Reference
       Region 3l3q A 71-497 order
Seq 71-529 Hetero dimer : B6VDJ7
 Evidence X-RAY 5fc8 E Reference
       Region 5fc8 E 71-497 order
       Region 5fc8 E 498-529 disorder
Seq 72-496 Hetero trimer : IID50235Complex
 Evidence X-RAY 3zin A Reference
       Region 3zin A 72-496 order
Seq 72-496 Hetero trimer :
 Evidence X-RAY 3zio A Reference
       Region 3zio A 72-496 order
Seq 72-496 Hetero trimer :
 Evidence X-RAY 2ynr A Reference
       Region 2ynr A 72-496 order
Seq 72-497 Hetero dimer : Q15020
 Evidence X-RAY 5ctt A Reference
       Region 5ctt A 72-497 order
Seq 72-497 Hetero trimer :
 Evidence X-RAY 3zir A Reference
       Region 3zir A 72-497 order
Seq 72-497 Hetero trimer :
 Evidence X-RAY 3ziq A Reference
       Region 3ziq A 72-497 order
Seq 72-497 Hetero trimer :
 Evidence X-RAY 3zip A Reference
       Region 3zip A 72-497 order
Seq 72-498 Hetero dimer : P03466
 Evidence X-RAY 4zdu A Reference
       Region 4zdu A 72-75 disorder
       Region 4zdu A 76-105 order
       Region 4zdu A 106-110 disorder
       Region 4zdu A 111-496 order
       Region 4zdu A 497-498 disorder
Seq 72-529 Hetero trimer : P35680
 Evidence X-RAY 5k9s A Reference
       Region 5k9s A 72-73 disorder
       Region 5k9s A 74-498 order
       Region 5k9s A 499-529 disorder
Seq 75-496 Hetero dimer :
 Evidence X-RAY 3tpm A Reference
       Region 3tpm A 75-496 order
Seq 75-498 Hetero dimer : IID50016Complex
 Evidence X-RAY 2c1m A Reference
       Region 2c1m A 75-498 order
SeqProS verified 44-54 This region takes an ordered structure when it binds upon another region of this protein. :
       Region 1ial A 44-54 order
       Region 3tpo A 44-54 order
       Region 1-70 disorder
SeqProS verified 45-53 This region takes an ordered structure when it binds upon another region of this protein. Hetero trimer :
       Region 1iq1 A 47-53 order
       Region 1iq1 B 45-53 order
       Region 1-70 disorder
Seqphosphorylation
    62-62 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
 
Prediction
DICHOT
Disorder 1-10,55-71,498-529
Known Domain 11-54,72-497
SCOPe RPS-Blast
     4b8jA 28-496 e-137 a.118.1.0 automated matches
SCOP Hmmer
     1wa5B_ 12-501 9e-128 a.118.1.1 beta-Catenin
Pfam RPS-Blast
     PF01749 15-96 3e-15 Importin beta binding domain
     PF04826 115-333 3e-10 Armadillo-like
     PF00514 325-362 2e-07 Armadillo/beta-catenin-like...
     PF00514 368-403 4e-06 Armadillo/beta-catenin-like...
     PF00514 411-447 2e-04 Armadillo/beta-catenin-like...
     PF16186 458-509 2e-19 Atypical Arm repeat
Pfam Hmmer
    PF01749 13-98 1.8e-33 Importin beta binding domain
    PF00514 109-149 1.2e-11 Armadillo/beta-catenin-lik...
    PF00514 151-190 8.6e-14 Armadillo/beta-catenin-lik...
    PF00514 194-238 4.2e-13 Armadillo/beta-catenin-lik...
    PF00514 250-279 1.1e-10 Armadillo/beta-catenin-lik...
    PF00514 283-321 4.5e-10 Armadillo/beta-catenin-lik...
    PF00514 324-364 3.5e-14 Armadillo/beta-catenin-lik...
    PF00514 367-405 1.3e-12 Armadillo/beta-catenin-lik...
    PF00514 410-447 8.6e-12 Armadillo/beta-catenin-lik...
    PF16186 458-509 2.4e-27 Atypical Arm repeat