Search Keyword:


Search option:


IID50068  Major prion protein (Bos taurus) P10279
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
xml
Experiment
264
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-30 Monomer :
 Evidence NMR 1skh A Reference
       Region 1skh A 1-30 order
       Region 1skh A 1-4 high_rmsd
       Region 1skh A 25-30 high_rmsd
Seqdisorder 1-30
 Evidence CD Reference
       Region 1-30 disorder
Seq 25-241 Monomer :
 Evidence NMR 1dx1 A Reference
       Region 1dx1 A 25-134 disorder
       Region 1dx1 A 135-238 order
       Region 1dx1 A 239-241 disorder
 Evidence NMR 1dwy A Reference
       Region 1dwy A 132-134 disorder
       Region 1dwy A 135-238 order
       Region 1dwy A 239-241 disorder
 Evidence NMR 1dwz A Reference
       Region 1dwz A 132-134 disorder
       Region 1dwz A 135-238 order
       Region 1dwz A 239-241 disorder
 Evidence NMR 1dx0 A Reference
       Region 1dx0 A 25-134 disorder
       Region 1dx0 A 135-238 order
       Region 1dx0 A 239-241 disorder
Seq 103-242 Hetero trimer :
 Evidence X-RAY 4yx2 A Reference
       Region 4yx2 A 103-135 disorder
       Region 4yx2 A 136-236 order
       Region 4yx2 A 237-242 disorder
Seq 107-115 Hetero trimer :
 Evidence X-RAY 2hh0 P Reference
       Region 2hh0 P 107-115 order
Seq 108-119 Homo dimer :
 Evidence NMR 2rsk C Reference
       Region 2rsk C 108-119 order
 Evidence NMR 2rsk D Reference
       Region 2rsk D 108-119 order
 Evidence NMR 2ru7 C Reference
       Region 2ru7 C 108-119 order
 Evidence NMR 2ru7 D Reference
       Region 2ru7 D 108-119 order
SeqProS verified 108-119 This region is ordered in the complex with RNA. Homo dimer :
       Region 2rsk C 108-119 order
       Region 2rsk D 108-119 order
       Region 2ru7 C 108-119 order
       Region 2ru7 D 108-119 order
       Region 1dx1 A 25-134 disorder
 
Prediction
DICHOT
Disorder 1-4,25-110,264-264
Known Domain 5-24,111-263
SCOPe RPS-Blast
     4hlsA 137-233 7e-40 d.6.1.1 Prion protein domain
SCOP Hmmer
     1y2sA_ 130-240 9.1e-50 Prion-like
Pfam RPS-Blast
     PF11587 5-30 2e-08 Major prion protein bPrPp - N ...
     PF00377 145-262 2e-47 Prion/Doppel alpha-helical ...
Pfam Hmmer
    PF11587 1-30 1.1e-22 Major prion protein bPrPp - N...
    PF00377 145-262 6e-41 Prion/Doppel alpha-helical d...