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IID50084  Nuclear receptor coactivator 1 (Mus musculus) P70365
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
1447
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 257-367 Monomer :
 Evidence X-RAY 5y7w A Reference
       Region 5y7w A 257-365 order
       Region 5y7w A 366-367 disorder
 Evidence X-RAY 5y7w B Reference
       Region 5y7w B 257-259 disorder
       Region 5y7w B 260-367 order
Seq 257-385 Hetero dimer : IID00047Complex
 Evidence X-RAY 5nwx A Reference
       Region 5nwx A 257-259 disorder
       Region 5nwx A 260-348 order
       Region 5nwx A 349-355 disorder
       Region 5nwx A 356-366 order
       Region 5nwx A 367-385 disorder
 Evidence X-RAY 1oj5 A Reference
       Region 1oj5 A 257-258 disorder
       Region 1oj5 A 259-349 order
       Region 1oj5 A 350-353 disorder
       Region 1oj5 A 354-367 order
       Region 1oj5 A 368-385 disorder
Seq 686-700 Hetero dimer : IID00361Complex
 Evidence X-RAY 2o9i C Reference
       Region 2o9i C 686-700 order
 Evidence X-RAY 2o9i D Reference
       Region 2o9i D 686-700 order
Seq 690-704 Hetero dimer : IID00013Complex
 Evidence X-RAY 4dma E Reference
       Region 4dma E 690-690 disorder
       Region 4dma E 691-701 order
       Region 4dma E 702-704 disorder
 Evidence X-RAY 4dma F Reference
       Region 4dma F 690-701 order
       Region 4dma F 702-704 disorder
SeqProS possible 686-700 LXXLL motif Hetero dimer : IID00361Complex
       Region 2o9i C 686-700 order
       Region 2o9i D 686-700 order
SeqProS possible 690-701 LXXLL motif Hetero dimer : IID00013Complex
       Region 4dma E 691-701 order
       Region 4dma F 690-701 order
Seqphosphorylation
    22-22 Phosphoserine
    372-372 Phosphoserine
    395-395 Phosphoserine
    518-518 Phosphoserine
    559-559 Phosphoserine
    570-570 Phosphoserine
    702-702 Phosphoserine
    1039-1039 Phosphoserine
    1185-1185 Phosphothreonine
    1191-1191 Phosphoserine
    1378-1378 Phosphoserine
Seqacetylation
    2-2 N-acetylserine
 
Prediction
DICHOT
Disorder 1-10,210-258,368-631,708-925,981-1447
Known Domain 11-209,259-367,632-707,926-980
SCOPe RPS-Blast
     1an4A1 32-85 2e-05 a.38.1.1 Mad protein
     4wn5A1 123-172 1e-06 d.110.3.0 automated matches
     1oj5A 259-367 6e-35 d.110.3.8 PAS domain of steroid receptor coactiv...
     1kbhA 930-973 3e-12 a.153.1.1 Nuclear receptor coactivator 1, NCOA1
SCOP Hmmer
     1hloA_ 14-87 4.6e-10 a.38.1.1 Mad protein
     1oj5A_ 120-186 3.3e-16 d.110.3.8 PAS domain of ...
     1oj5A_ 260-365 1.2e-22 d.110.3.8 PAS domain of ...
     2c52B1 926-972 2e-17 a.153.1.1 Nuclear receptor...
Pfam RPS-Blast
     PF14598 260-368 7e-25 PAS domain
     PF16665 468-591 2e-25 Unstructured region on nucl...
     PF08832 636-712 1e-08 Steroid receptor coactivato...
     PF16279 750-828 8e-08 Domain of unknown function ...
     PF08815 930-972 3e-11 Nuclear receptor coactivato...
     PF13779 1045-1152 1e-04 Domain of unknown functio...
     PF07469 1155-1210 8e-07 Domain of unknown functio...
     PF07469 1218-1274 5e-06 Domain of unknown functio...
Pfam Hmmer
    PF00010 30-80 4.1e-08 Helix-loop-helix DNA-binding...
    PF00989 115-172 1.5e-10 PAS fold
    PF14598 260-369 1.4e-37 PAS domain
    PF16665 469-591 1.2e-29 Unstructured region on nuc...
    PF08832 634-712 1.3e-26 Steroid receptor coactivat...
    PF08815 930-975 2.4e-24 Nuclear receptor coactivat...
    PF07469 1155-1210 8.5e-19 Domain of unknown functi...
    PF07469 1218-1273 2.5e-16 Domain of unknown functi...