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IID50157  Neurogenic locus Notch protein (Drosophila melanogaster) P07207
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
2703
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seqdisorder 1768-1900
 Evidence CD Reference
       Region 1768-1900 disorder
Seq 1902-2139 Monomer :
 Evidence X-RAY 1ot8 A Reference
       Region 1ot8 A 1902-1928 disorder
       Region 1ot8 A 1929-2137 order
       Region 1ot8 A 2138-2139 disorder
 Evidence X-RAY 1ot8 B Reference
       Region 1ot8 B 1902-1935 disorder
       Region 1ot8 B 1936-2139 order
 Evidence X-RAY 1ot8 C Reference
       Region 1ot8 C 1902-1946 disorder
       Region 1ot8 C 1947-2138 order
       Region 1ot8 C 2139-2139 disorder
Seq 2318-2333 Hetero dimer : IID50161Complex
 Evidence NMR 2jmf B Reference
       Region 2jmf B 2318-2318 disorder
       Region 2jmf B 2319-2333 order
       Region 2jmf B 2319-2320 high_rmsd
Seqphosphorylation
    2447-2447 Phosphoserine
 
Prediction
DICHOT
Disorder 1-20,44-60,1023-1030,1336-1337,1453-1481,1698-1893,2138-2703
Known Domain 21-43,61-1022,1031-1335,1338-1452,1482-1697,1894-2137
SCOPe RPS-Blast
     1egfA 143-180 2e-05 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 181-214 4e-06 g.3.11.1 Activated protein c (autoprothrombin II...
     5mwbA1 217-254 4e-09 g.3.11.0 automated matches
     1edmB 259-291 1e-05 g.3.11.1 Activated protein c (autoprothrombin II...
     1g1tA2 295-332 3e-08 g.3.11.1 Activated protein c (autoprothrombin I...
     5mwbA1 331-372 5e-08 g.3.11.0 automated matches
     1g1tA2 373-407 5e-04 g.3.11.1 Activated protein c (autoprothrombin I...
     5mwbA1 449-488 1e-10 g.3.11.0 automated matches
     1edmB 487-525 1e-09 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 525-563 9e-12 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 563-601 6e-11 g.3.11.1 Activated protein c (autoprothrombin II...
     1autL1 598-641 5e-10 g.3.11.1 Activated protein c (autoprothrombin I...
     1g1tA2 641-678 4e-06 g.3.11.1 Activated protein c (autoprothrombin I...
     1edmB 676-713 1e-12 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 715-750 7e-09 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 753-790 4e-11 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 791-828 3e-11 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 828-865 5e-09 g.3.11.1 Activated protein c (autoprothrombin II...
     5mwbA1 907-946 2e-08 g.3.11.0 automated matches
     1edmB 945-983 4e-11 g.3.11.1 Activated protein c (autoprothrombin II...
     1edmB 983-1021 3e-12 g.3.11.1 Activated protein c (autoprothrombin I...
     1edmB 1021-1058 8e-08 g.3.11.1 Activated protein c (autoprothrombin ...
     1edmB 1062-1095 9e-09 g.3.11.1 Activated protein c (autoprothrombin ...
     1edmB 1183-1220 7e-11 g.3.11.1 Activated protein c (autoprothrombin ...
     1edmB 1221-1258 2e-09 g.3.11.1 Activated protein c (autoprothrombin ...
     1g1tA2 1261-1298 2e-07 g.3.11.1 Activated protein c (autoprothrombin...
     1edmB 1297-1335 2e-07 g.3.11.1 Activated protein c (autoprothrombin ...
     1edmB 1338-1374 5e-04 g.3.11.1 Activated protein c (autoprothrombin ...
     1edmB 1417-1452 2e-05 g.3.11.1 Activated protein c (autoprothrombin ...
     1pb5A 1479-1513 3e-05 g.65.1.1 Neurogenic locus notch homolog protei...
     2f8yA 1932-2144 1e-84 d.211.1.1 26S proteasome non-ATPase regulator...
SCOP Hmmer
     1haeA_ 61-96 1.1e-06 g.3.11.1 Activated protein...
     1haeA_ 97-140 1.1e-06 g.3.11.1 Activated protei...
     1p9jA_ 143-177 8.4e-09 g.3.11.1 Activated prote...
     1gk5A_ 178-221 2.3e-10 g.3.11.1 Activated prote...
     2dtgE6 205-335 1.4e-15 g.3.9.1 EGF receptor Cys...
     1tozA1 331-370 1.2e-09 g.3.11.1 Activated prote...
     1ccfA_ 372-410 4.7e-08 g.3.11.1 Activated prote...
     1nqlB_ 411-453 2.2e-08 g.3.11.1 Activated prote...
     1tozA1 449-487 9.9e-11 g.3.11.1 Activated prote...
     1ffmA_ 488-530 3.4e-13 g.3.11.1 Activated prote...
     2dtgE6 513-643 3.4e-14 g.3.9.1 EGF receptor Cys...
     2dtgE6 589-720 4.3e-18 g.3.9.1 EGF receptor Cys...
     2dtgE6 664-795 2e-16 g.3.9.1 EGF receptor Cys-r...
     1ffmA_ 791-831 2.5e-14 g.3.11.1 Activated prote...
     1ffmA_ 829-872 1.5e-12 g.3.11.1 Activated prote...
     1haeA_ 867-912 1.3e-09 g.3.11.1 Activated prote...
     2dtgE6 894-1026 2.5e-14 g.3.9.1 EGF receptor Cy...
     1ffmA_ 1024-1065 1.4e-10 g.3.11.1 Activated pro...
     1ffmA_ 1061-1098 7.2e-11 g.3.11.1 Activated pro...
     1haeA_ 1099-1141 3e-09 g.3.11.1 Activated prote...
     1autL1 1153-1187 5.1e-07 g.3.11.1 Activated pro...
     1ffmA_ 1183-1225 8.4e-14 g.3.11.1 Activated pro...
     2dtgE6 1208-1344 1.9e-13 g.3.9.1 EGF receptor C...
     1ffmA_ 1338-1375 3.3e-09 g.3.11.1 Activated pro...
     1gk5A_ 1377-1415 3.1e-06 g.3.11.1 Activated pro...
     1ffmA_ 1416-1453 2e-10 g.3.11.1 Activated prote...
     1pb5A_ 1481-1513 1e-07 g.65.1.1 Neurogenic locu...
     1pb5A_ 1521-1553 4.8e-08 g.65.1.1 Neurogenic lo...
     1pb5A_ 1561-1593 1.2e-08 g.65.1.1 Neurogenic lo...
     1s70B_ 1892-2139 2e-54 d.211.1.1 26S proteasome...
Pfam RPS-Blast
     PF00008 221-250 4e-05 EGF-like domain
     PF00008 259-289 9e-05 EGF-like domain
     PF00008 492-520 4e-04 EGF-like domain
     PF00008 530-560 2e-05 EGF-like domain
     PF00008 568-596 6e-04 EGF-like domain
     PF00008 681-711 1e-05 EGF-like domain
     PF00008 757-787 4e-05 EGF-like domain
     PF00008 795-823 2e-05 EGF-like domain
     PF00008 833-862 4e-04 EGF-like domain
     PF00008 950-980 3e-05 EGF-like domain
     PF00008 988-1018 5e-05 EGF-like domain
     PF00008 1064-1093 1e-05 EGF-like domain
     PF00008 1187-1217 2e-05 EGF-like domain
     PF00008 1225-1253 3e-04 EGF-like domain
     PF00066 1564-1592 8e-04 LNR domain
     PF06816 1599-1652 1e-14 NOTCH protein
     PF07684 1679-1731 3e-13 NOTCH protein
     PF13857 1936-1989 1e-10 Ankyrin repeats (many cop...
     PF13857 2003-2056 1e-07 Ankyrin repeats (many cop...
     PF13857 2041-2091 1e-10 Ankyrin repeats (many cop...
     PF13857 2070-2124 5e-05 Ankyrin repeats (many cop...
     PF12851 2133-2627 2e-10 Oxygenase domain of the 2...
     PF11936 2627-2682 3e-16 Domain of unknown functio...
Pfam Hmmer
    PF00008 100-132 3.5e-09 EGF-like domain
    PF00008 147-174 5.3e-09 EGF-like domain
    PF00008 181-213 1.9e-09 EGF-like domain
    PF00008 221-250 6.8e-11 EGF-like domain
    PF00008 259-289 2.7e-10 EGF-like domain
    PF00008 299-326 5.4e-09 EGF-like domain
    PF07645 331-371 2.7e-11 Calcium-binding EGF domain
    PF00008 413-443 2.1e-08 EGF-like domain
    PF07645 449-481 8.9e-12 Calcium-binding EGF domain
    PF00008 492-520 3.6e-09 EGF-like domain
    PF00008 530-560 4.4e-11 EGF-like domain
    PF00008 568-596 9.8e-10 EGF-like domain
    PF00008 606-633 1.9e-09 EGF-like domain
    PF00008 681-711 8.3e-12 EGF-like domain
    PF12661 724-745 3.2e-09 Human growth factor-like E...
    PF00008 757-787 2.3e-10 EGF-like domain
    PF00008 795-824 4.9e-10 EGF-like domain
    PF00008 833-862 2.8e-10 EGF-like domain
    PF00008 871-903 1.5e-08 EGF-like domain
    PF07645 907-939 1.7e-11 Calcium-binding EGF domain
    PF00008 950-980 1.3e-11 EGF-like domain
    PF00008 988-1018 4.5e-11 EGF-like domain
    PF12661 1031-1052 2e-08 Human growth factor-like E...
    PF00008 1064-1093 6e-11 EGF-like domain
    PF00008 1102-1131 1.3e-08 EGF-like domain
    PF00008 1187-1216 1.4e-10 EGF-like domain
    PF00008 1225-1250 5.4e-08 EGF-like domain
    PF00008 1263-1293 2.5e-09 EGF-like domain
    PF00008 1419-1449 2.8e-08 EGF-like domain
    PF00066 1481-1513 1.7e-11 LNR domain
    PF00066 1519-1553 4.9e-14 LNR domain
    PF00066 1558-1593 6.9e-13 LNR domain
    PF06816 1599-1652 6.5e-21 NOTCH protein
    PF07684 1679-1730 1.4e-19 NOTCH protein
    PF00023 1902-1946 5.1e-08 Ankyrin repeat
    PF13857 1948-1989 9.5e-11 Ankyrin repeats (many co...
    PF12796 2023-2111 4e-16 Ankyrin repeats (3 copies)
    PF11936 2628-2682 2.7e-19 Domain of unknown functi...