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IID50282  Tyrosine-protein kinase SYK (Mus musculus) P48025
  :order  :disorder  :conflict  :PDB cluster  :ProS  :SCOP Domain  :Pfam Domain
Networkxml
Experiment
629
fasta
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 338-350 Hetero dimer : IID00652Complex
 Evidence NMR 2lct B Reference
       Region 2lct B 338-350 order
 Evidence NMR 2mc1 B Reference
       Region 2mc1 B 338-350 order
Seqphosphorylation
    27-27 Phosphotyrosine
    43-43 Phosphoserine
    46-46 Phosphotyrosine
    130-130 Phosphotyrosine
    201-201 Phosphoserine
    255-255 Phosphothreonine
    270-270 Phosphoserine
    289-289 Phosphoserine
    290-290 Phosphotyrosine
    291-291 Phosphoserine
    310-310 Phosphoserine
    311-311 Phosphothreonine
    313-313 Phosphoserine
    317-317 Phosphotyrosine; by LYN
    339-339 Phosphothreonine
    342-342 Phosphotyrosine
    344-344 Phosphoserine
    346-346 Phosphotyrosine
    358-358 Phosphotyrosine
    373-373 Phosphoserine
    378-378 Phosphothreonine
    478-478 Phosphotyrosine
    501-501 Phosphotyrosine
    519-519 Phosphotyrosine; by autocatalysis
    520-520 Phosphotyrosine
    524-524 Phosphothreonine
    540-540 Phosphotyrosine
    573-573 Phosphoserine
    576-576 Phosphothreonine
    623-623 Phosphotyrosine
    624-624 Phosphotyrosine
    625-625 Phosphotyrosine
 
Prediction
DICHOT
Disorder 1-7
Known Domain 8-629
SCOPe RPS-Blast
     2oq1A1 7-136 4e-43 d.93.1.1 Abl tyrosine kinase
     2oq1A2 137-258 2e-45 d.93.1.1 Abl tyrosine kinase
     4fyoA1 357-629 e-125 d.144.1.7 3-phosphoinositide dependent protein...
SCOP Hmmer
     1a81A1 11-136 1.1e-32 d.93.1.1 Abl tyrosine kin...
     1m61A2 146-259 6.2e-33 d.93.1.1 Abl tyrosine ki...
     1m14A_ 369-621 3.8e-72 d.144.1.7 3-phosphoinosi...
Pfam RPS-Blast
     PF00017 167-243 7e-06 SH2 domain
Pfam Hmmer
    PF00017 14-91 1.5e-22 SH2 domain
    PF00017 167-243 1.2e-24 SH2 domain
    PF07714 369-617 1e-92 Protein tyrosine kinase