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IID50297
 UniprotG0SDW4
ProteinUncharacterized protein
GeneCTHT_0053230
OrganismChaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
1522
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 191-950 Hetero dimer : G0RYC6,G0S8H7
 Evidence X-RAY 5kji B Reference
       Region 5kji B 191-195 disorder
       Region 5kji B 196-253 order
       Region 5kji B 254-262 disorder
       Region 5kji B 263-319 order
       Region 5kji B 320-360 disorder
       Region 5kji B 361-404 order
       Region 5kji B 405-410 disorder
       Region 5kji B 411-428 order
       Region 5kji B 429-432 disorder
       Region 5kji B 433-452 order
       Region 5kji B 453-453 disorder
       Region 5kji B 454-473 order
       Region 5kji B 474-489 disorder
       Region 5kji B 490-553 order
       Region 5kji B 554-567 disorder
       Region 5kji B 568-581 order
       Region 5kji B 582-583 disorder
       Region 5kji B 584-609 order
       Region 5kji B 610-610 disorder
       Region 5kji B 611-640 order
       Region 5kji B 641-646 disorder
       Region 5kji B 647-738 order
       Region 5kji B 739-739 disorder
       Region 5kji B 740-842 order
       Region 5kji B 843-851 disorder
       Region 5kji B 852-921 order
       Region 5kji B 922-924 disorder
       Region 5kji B 925-928 order
       Region 5kji B 929-950 disorder
Seq 191-950 Hetero trimer : G0RYC6,G0S8H7,IID00062Complex
 Evidence X-RAY 5kkl B Reference
       Region 5kkl B 191-196 disorder
       Region 5kkl B 197-251 order
       Region 5kkl B 252-261 disorder
       Region 5kkl B 262-406 order
       Region 5kkl B 407-409 disorder
       Region 5kkl B 410-479 order
       Region 5kkl B 480-489 disorder
       Region 5kkl B 490-556 order
       Region 5kkl B 557-567 disorder
       Region 5kkl B 568-740 order
       Region 5kkl B 741-742 disorder
       Region 5kkl B 743-848 order
       Region 5kkl B 849-851 disorder
       Region 5kkl B 852-927 order
       Region 5kkl B 928-950 disorder
Seq 191-950 Hetero trimer : G0RYC6,G0S8H7,IID00062Complex
 Evidence X-RAY 5kjh B Reference
       Region 5kjh B 191-196 disorder
       Region 5kjh B 197-356 order
       Region 5kjh B 357-359 disorder
       Region 5kjh B 360-391 order
       Region 5kjh B 392-392 disorder
       Region 5kjh B 393-407 order
       Region 5kjh B 408-412 disorder
       Region 5kjh B 413-427 order
       Region 5kjh B 428-432 disorder
       Region 5kjh B 433-451 order
       Region 5kjh B 452-454 disorder
       Region 5kjh B 455-473 order
       Region 5kjh B 474-489 disorder
       Region 5kjh B 490-552 order
       Region 5kjh B 553-567 disorder
       Region 5kjh B 568-575 order
       Region 5kjh B 576-576 disorder
       Region 5kjh B 577-580 order
       Region 5kjh B 581-587 disorder
       Region 5kjh B 588-608 order
       Region 5kjh B 609-610 disorder
       Region 5kjh B 611-621 order
       Region 5kjh B 622-622 disorder
       Region 5kjh B 623-640 order
       Region 5kjh B 641-646 disorder
       Region 5kjh B 647-740 order
       Region 5kjh B 741-742 disorder
       Region 5kjh B 743-848 order
       Region 5kjh B 849-851 disorder
       Region 5kjh B 852-929 order
       Region 5kjh B 930-950 disorder
Seq 191-950 Hetero dimer : G0RYC6,G0S8H7
 Evidence X-RAY 5vk3 B Reference
       Region 5vk3 B 191-194 disorder
       Region 5vk3 B 195-253 order
       Region 5vk3 B 254-259 disorder
       Region 5vk3 B 260-325 order
       Region 5vk3 B 326-359 disorder
       Region 5vk3 B 360-479 order
       Region 5vk3 B 480-490 disorder
       Region 5vk3 B 491-554 order
       Region 5vk3 B 555-566 disorder
       Region 5vk3 B 567-579 order
       Region 5vk3 B 580-587 disorder
       Region 5vk3 B 588-846 order
       Region 5vk3 B 847-852 disorder
       Region 5vk3 B 853-928 order
       Region 5vk3 B 929-950 disorder
Seq 191-950 Hetero dimer : G0RYC6,G0S8H7
 Evidence X-RAY 5bjs B Reference
       Region 5bjs B 191-195 disorder
       Region 5bjs B 196-253 order
       Region 5bjs B 254-258 disorder
       Region 5bjs B 259-326 order
       Region 5bjs B 327-356 disorder
       Region 5bjs B 357-408 order
       Region 5bjs B 409-409 disorder
       Region 5bjs B 410-479 order
       Region 5bjs B 480-490 disorder
       Region 5bjs B 491-552 order
       Region 5bjs B 553-566 disorder
       Region 5bjs B 567-580 order
       Region 5bjs B 581-587 disorder
       Region 5bjs B 588-644 order
       Region 5bjs B 645-647 disorder
       Region 5bjs B 648-848 order
       Region 5bjs B 849-850 disorder
       Region 5bjs B 851-933 order
       Region 5bjs B 934-950 disorder
Seq 191-950 Hetero dimer : G0RYC6,G0S8H7
 Evidence X-RAY 5tqr B Reference
       Region 5tqr B 191-194 disorder
       Region 5tqr B 195-255 order
       Region 5tqr B 256-258 disorder
       Region 5tqr B 259-326 order
       Region 5tqr B 327-356 disorder
       Region 5tqr B 357-479 order
       Region 5tqr B 480-490 disorder
       Region 5tqr B 491-554 order
       Region 5tqr B 555-566 disorder
       Region 5tqr B 567-580 order
       Region 5tqr B 581-587 disorder
       Region 5tqr B 588-845 order
       Region 5tqr B 846-848 disorder
       Region 5tqr B 849-933 order
       Region 5tqr B 934-950 disorder
Seq 191-952 Hetero tetramer : G0RYC6,G0S8H7,IID00062Complex
 Evidence X-RAY 5m5g B Reference
       Region 5m5g B 191-196 disorder
       Region 5m5g B 197-356 order
       Region 5m5g B 357-359 disorder
       Region 5m5g B 360-391 order
       Region 5m5g B 392-392 disorder
       Region 5m5g B 393-407 order
       Region 5m5g B 408-412 disorder
       Region 5m5g B 413-427 order
       Region 5m5g B 428-432 disorder
       Region 5m5g B 433-451 order
       Region 5m5g B 452-454 disorder
       Region 5m5g B 455-473 order
       Region 5m5g B 474-489 disorder
       Region 5m5g B 490-552 order
       Region 5m5g B 553-567 disorder
       Region 5m5g B 568-575 order
       Region 5m5g B 576-576 disorder
       Region 5m5g B 577-580 order
       Region 5m5g B 581-587 disorder
       Region 5m5g B 588-608 order
       Region 5m5g B 609-610 disorder
       Region 5m5g B 611-621 order
       Region 5m5g B 622-622 disorder
       Region 5m5g B 623-640 order
       Region 5m5g B 641-646 disorder
       Region 5m5g B 647-740 order
       Region 5m5g B 741-742 disorder
       Region 5m5g B 743-848 order
       Region 5m5g B 849-851 disorder
       Region 5m5g B 852-929 order
       Region 5m5g B 930-952 disorder
SeqProS verified 320-356 stimulatory-responsive motif (SRM) (PubMed=28008038) Hetero trimer : G0RYC6,G0S8H7,IID00062Complex
       Region 5kkl B 262-406 order
       Region 5kji B 320-360 disorder
SeqProS verified 320-356 stimulatory-responsive motif (SRM) (PubMed=28008038) Hetero trimer : G0RYC6,G0S8H7,IID00062Complex
       Region 5kjh B 197-356 order
       Region 5kji B 320-360 disorder
SeqProS verified 320-356 stimulatory-responsive motif (SRM) (PubMed=28008038) Hetero tetramer : G0RYC6,G0S8H7,IID00062Complex
       Region 5m5g B 197-356 order
       Region 5kji B 320-360 disorder
 
Prediction
NeProc
Disorder 1-193,250-267,276-284,477-493,529-576,579-580,642-672,933-988,1028-1062,1091-1205,1238-1522
Order 194-249,268-275,285-476,494-528,577-578,586-641,673-932,989-1027,1063-1090,1206-1237
ProS 6-59,77-88,266-267,477-480,529-551,567-576,651-672,933-936,972-977,986-988,1060-1062,1119-1124,1163-1167,1238-1238,1248-1255,1261-1267,1283-1298,1309-1312,1341-1350,1356-1365,1389-1412,1420-1430,1435-1444,1488-1492,1500-1507,1515-1522
AlphaFold
Disorder 1-49,56-195,256-258,326-330,355-355,358-358,479-490,557-566,846-852,930-930,932-994,996-996,1022-1059,1089-1522
Order 50-55,196-255,259-325,331-354,356-357,359-478,491-556,567-845,853-929,931-931,995-995,997-1021,1060-1088
Pfam Hmmer
PF00856 789-926 6.3e-38
SEG 27-50 ,64-76 ,100-130 ,179-195 ,951-986 ,992-1024 ,1072-1091 ,1096-1106 ,1141-1158 ,1161-1192 ,1206-1235 ,1255-1268 ,1274-1299 ,1355-1385 ,1392-1403 ,1415-1428 ,1465-1500
Function
Biological Process
Diagram with PDB data
CTHT_0053230/CTHT_0029920/CTHT_0006210/H3C1/H3C1Structure of ctPRC2 in complex with H3K27me3 and H3K27M