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IID50356
 UniprotP10085
ProteinMyoblast determination protein 1
GeneMyod1
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
318
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 102-166 Hetero dimer : P15806
 Evidence X-RAY 7wz6 B Reference
       Region 7wz6 B 102-115 disorder
       Region 7wz6 B 116-165 order
       Region 7wz6 B 166-166 disorder
Seq 102-166 Homo dimer :
 Evidence X-RAY 1mdy A Reference
       Region 1mdy A 102-166 order
 Evidence X-RAY 1mdy B Reference
       Region 1mdy B 105-166 order
 Evidence X-RAY 1mdy C Reference
       Region 1mdy C 105-166 order
 Evidence X-RAY 1mdy D Reference
       Region 1mdy D 105-166 order
SeqProS verified 102-115 DNA binding Homo dimer :
       Region 1mdy A 102-166 order
       Region 1mdy B 105-166 order
       Region 1mdy C 105-166 order
       Region 1mdy D 105-166 order
       Region 7wz6 B 102-115 disorder
 
Prediction
NeProc
Disorder 1-124,169-318
Order 125-168
ProS 1-61,80-97,107-124,202-259,299-304,311-318
AlphaFold
Disorder 1-92,100-100,103-103,170-244,261-318
Order 93-99,101-102,104-169,245-260
Pfam Hmmer
PF01586 1-109 3.8e-43
PF00010 110-161 5e-19
SEG 110-121 ,169-186 ,261-286
Function
Function in SwissProt
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:16901893). Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (PubMed:21798092, PubMed:3175662).