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IID50375
 UniprotP63248
ProteincAMP-dependent protein kinase inhibitor alpha
GenePkia
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
76
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 6-25 Hetero dimer : IID50138Complex
 Evidence X-RAY 1apm I Reference
       Region 1apm I 6-25 order
 Evidence X-RAY 1atp I Reference
       Region 1atp I 6-25 order
 Evidence X-RAY 2cpk I Reference
       Region 2cpk I 6-25 order
 Evidence X-RAY 2qur B Reference
       Region 2qur B 6-25 order
 Evidence X-RAY 3fjq I Reference
       Region 3fjq I 6-24 order
       Region 3fjq I 25-25 disorder
 Evidence X-RAY 3ow3 B Reference
       Region 3ow3 B 6-24 order
       Region 3ow3 B 25-25 disorder
 Evidence X-RAY 3qal I Reference
       Region 3qal I 6-23 order
 Evidence X-RAY 3qam I Reference
       Region 3qam I 6-24 order
 Evidence X-RAY 4dfx I Reference
       Region 4dfx I 6-25 order
 Evidence X-RAY 4dfz I Reference
       Region 4dfz I 6-25 order
 Evidence X-RAY 4dg0 I Reference
       Region 4dg0 I 6-25 order
 Evidence X-RAY 4dg2 I Reference
       Region 4dg2 I 6-25 order
 Evidence X-RAY 4dg3 A Reference
       Region 4dg3 A 6-24 order
       Region 4dg3 A 25-25 disorder
 Evidence X-RAY 4dh1 I Reference
       Region 4dh1 I 6-25 order
 Evidence X-RAY 4dh3 I Reference
       Region 4dh3 I 6-25 order
 Evidence X-RAY 4dh5 I Reference
       Region 4dh5 I 6-25 order
 Evidence X-RAY 4dh7 I Reference
       Region 4dh7 I 6-25 order
 Evidence X-RAY 4dh8 I Reference
       Region 4dh8 I 6-25 order
 Evidence X-RAY 4hpt I Reference
       Region 4hpt I 6-24 order
       Region 4hpt I 25-25 disorder
 Evidence X-RAY 4hpu I Reference
       Region 4hpu I 6-24 order
       Region 4hpu I 25-25 disorder
Seq 6-25 Hetero dimer : IID50134Complex
 Evidence X-RAY 2gnf I Reference
       Region 2gnf I 6-25 order
 Evidence X-RAY 2gng I Reference
       Region 2gng I 6-25 order
Seq 6-25 Hetero dimer : P25321
 Evidence X-RAY 6f14 B Reference
       Region 6f14 B 6-23 order
       Region 6f14 B 24-25 disorder
 Evidence X-RAY 6y05 B Reference
       Region 6y05 B 6-23 order
       Region 6y05 B 24-25 disorder
 Evidence X-RAY 6y0b B Reference
       Region 6y0b B 6-24 order
       Region 6y0b B 25-25 disorder
 Evidence X-RAY 6y2o B Reference
       Region 6y2o B 6-23 order
       Region 6y2o B 24-25 disorder
 Evidence X-RAY 6y8c B Reference
       Region 6y8c B 6-23 order
       Region 6y8c B 24-25 disorder
 Evidence X-RAY 6ynr B Reference
       Region 6ynr B 6-24 order
       Region 6ynr B 25-25 disorder
 Evidence X-RAY 6ynt B Reference
       Region 6ynt B 6-24 order
       Region 6ynt B 25-25 disorder
Seq 12-30 Hetero dimer : P25321
 Evidence X-RAY 6yna B Reference
       Region 6yna B 12-13 disorder
       Region 6yna B 14-26 order
       Region 6yna B 27-30 disorder
 Evidence X-RAY 6ynb B Reference
       Region 6ynb B 12-13 disorder
       Region 6ynb B 14-26 order
       Region 6ynb B 27-30 disorder
 Evidence X-RAY 6ync B Reference
       Region 6ync B 12-13 disorder
       Region 6ync B 14-27 order
       Region 6ync B 28-30 disorder
 Evidence X-RAY 6yqi B Reference
       Region 6yqi B 12-13 disorder
       Region 6yqi B 14-26 order
       Region 6yqi B 27-30 disorder
 Evidence X-RAY 6yqj B Reference
       Region 6yqj B 12-13 disorder
       Region 6yqj B 14-26 order
       Region 6yqj B 27-30 disorder
 Evidence X-RAY 6yqk B Reference
       Region 6yqk B 12-13 disorder
       Region 6yqk B 14-26 order
       Region 6yqk B 27-30 disorder
SeqProS possible 6-27 Same region of the rabbit ortholog (P61926, 97.4% identity) is disordered in the free state. Hetero dimer : IID50134Complex
       Region 2gng I 6-25 order
       Region 2gnf I 6-25 order
SeqProS possible 6-27 Same region of the rabbit ortholog (P61926, 97.4% identity) is disordered in the free state. Hetero dimer : P25321
       Region 6yqi B 14-26 order
       Region 6yna B 14-26 order
       Region 6ync B 14-27 order
       Region 6ynb B 14-26 order
       Region 6yqj B 14-26 order
       Region 6yqk B 14-26 order
SeqProS possible 6-27 Same region of the rabbit ortholog (P61926, 97.4% identity) is disordered in the free state. Hetero dimer : IID50138Complex
       Region 4dh5 I 6-25 order
       Region 1atp I 6-25 order
       Region 4dh8 I 6-25 order
       Region 4dfx I 6-25 order
       Region 2qur B 6-25 order
       Region 4hpu I 6-24 order
       Region 4dh3 I 6-25 order
       Region 4dg0 I 6-25 order
       Region 4hpt I 6-24 order
       Region 3ow3 B 6-24 order
       Region 3qal I 6-23 order
       Region 4dfz I 6-25 order
       Region 4dh7 I 6-25 order
       Region 4dg2 I 6-25 order
       Region 3qam I 6-24 order
       Region 4dg3 A 6-24 order
       Region 4dh1 I 6-25 order
       Region 3fjq I 6-24 order
       Region 2cpk I 6-25 order
       Region 1apm I 6-25 order
SeqProS possible 6-27 Same region of the rabbit ortholog (P61926, 97.4% identity) is disordered in the free state. Hetero dimer : P25321
       Region 6y0b B 6-24 order
       Region 6ynt B 6-24 order
       Region 6y05 B 6-23 order
       Region 6y8c B 6-23 order
       Region 6y2o B 6-23 order
       Region 6ynr B 6-24 order
       Region 6f14 B 6-23 order
Seqacetylation
    2-2 N-acetylthreonine
 
Prediction
NeProc
Disorder 1-9,15-22,29-76
Order 10-14,23-28
ProS 4-9,15-22,35-50
AlphaFold
Disorder 1-1,15-34,52-76
Order 2-14,35-51
Pfam Hmmer
PF02827 2-75 2e-48
Function
Function in SwissProt
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.