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IID50376
 UniprotP63249
ProteincAMP-dependent protein kinase inhibitor alpha
GenePkia
OrganismRattus norvegicus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
76
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 6-25 Hetero dimer : IID50134Complex
 Evidence X-RAY 1q62 I Reference
       Region 1q62 I 6-25 order
 Evidence X-RAY 1q8u B Reference
       Region 1q8u B 6-25 order
 Evidence X-RAY 1svh B Reference
       Region 1svh B 6-24 order
       Region 1svh B 25-25 disorder
 Evidence X-RAY 1yds I Reference
       Region 1yds I 6-25 order
 Evidence X-RAY 1ydt I Reference
       Region 1ydt I 6-25 order
Seq 6-25 Hetero dimer : IID50138Complex
 Evidence X-RAY 1l3r I Reference
       Region 1l3r I 6-25 order
SeqProS possible 6-25 Same region of the rabbit ortholog (P61926, 97.4% identity) is disordered in the free state. Hetero dimer : IID50138Complex
       Region 1l3r I 6-25 order
SeqProS possible 6-25 Same region of the rabbit ortholog (P61926, 97.4% identity) is disordered in the free state. Hetero dimer : IID50134Complex
       Region 1q8u B 6-25 order
       Region 1q62 I 6-25 order
       Region 1svh B 6-24 order
       Region 1ydt I 6-25 order
       Region 1yds I 6-25 order
Seqacetylation
    2-2 N-acetylthreonine
 
Prediction
NeProc
Disorder 1-9,15-22,29-76
Order 10-14,23-28
ProS 4-9,15-22,35-50
AlphaFold
Disorder 1-1,14-34,52-76
Order 2-13,35-51
Pfam Hmmer
PF02827 2-75 2e-48
Function
Function in SwissProt
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.