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IID50384
 UniprotQ03390
ProteinVacuolar protein-sorting-associated protein 60
GeneVPS60
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
229
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 128-186 Hetero dimer : IID50386Complex
 Evidence NMR 2luh B Reference
       Region 2luh B 128-186 order
SeqProS possible 128-186 Same region of the human homolog (Q9NZZ3, CHMP5) is disordered (PubMed=22484091). Hetero dimer : IID50386Complex
       Region 2luh B 128-186 order
 
Prediction
NeProc
Disorder 1-20,161-229
Order 21-160
ProS 1-7,17-20,161-180,197-213,221-229
AlphaFold
Disorder 1-10,128-128,133-133,151-151,153-166,182-229
Order 11-127,129-132,134-150,152-152,167-181
Pfam Hmmer
PF03357 19-214 1.7e-65
SEG 162-182
Function
Function in SwissProt
Has a role in a late stage of multivesicular body (MVB) formation. Can stimulate VPS4 ATPase activity via VTA1.