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IID50398
 UniprotQ80TS7
ProteinDendrin
GeneDdn
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
710
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 222-235 Hetero tetramer : Q9WVQ1
 Evidence X-RAY 6jjz C Reference
       Region 6jjz C 222-234 order
       Region 6jjz C 235-235 disorder
 Evidence X-RAY 6jjz D Reference
       Region 6jjz D 222-234 order
       Region 6jjz D 235-235 disorder
Seq 222-241 Hetero tetramer : IID50281Complex
 Evidence X-RAY 6jk1 A Reference
       Region 6jk1 A 222-241 order
 Evidence X-RAY 6jk1 B Reference
       Region 6jk1 B 222-241 order
Seq 222-241 Hetero dimer : IID50281Complex
 Evidence X-RAY 6jk0 A Reference
       Region 6jk0 A 222-241 order
Seq 222-241 Hetero tetramer : Q9WVQ1
 Evidence X-RAY 6kkg C Reference
       Region 6kkg C 222-241 order
 Evidence X-RAY 6kkg D Reference
       Region 6kkg D 222-241 order
Seq 222-246 Hetero dimer : Q5SXA9
 Evidence X-RAY 6j69 B Reference
       Region 6j69 B 222-239 order
       Region 6j69 B 240-246 disorder
Seq 225-235 Hetero dimer : IID50401Complex
 Evidence X-RAY 7bqg A Reference
       Region 7bqg A 225-235 order
SeqProS possible 222-239 PPxY motif Hetero dimer : Q5SXA9
       Region 6j69 B 222-239 order
SeqProS possible 222-241 PPxY motif Hetero tetramer : Q9WVQ1
       Region 6jjz C 222-234 order
       Region 6jjz D 222-234 order
SeqProS possible 222-241 PPxY motif Hetero tetramer : IID50281Complex
       Region 6jk1 A 222-241 order
       Region 6jk1 B 222-241 order
SeqProS possible 222-241 PPxY motif Hetero dimer : IID50281Complex
       Region 6jk0 A 222-241 order
SeqProS possible 222-241 PPxY motif Hetero tetramer : Q9WVQ1
       Region 6kkg C 222-241 order
       Region 6kkg D 222-241 order
SeqProS possible 225-235 PPxY motif Hetero dimer : IID50401Complex
       Region 7bqg A 225-235 order
Seqphosphorylation
    388-388 Phosphoserine
 
Prediction
NeProc
Disorder 1-22,36-41,49-107,136-710
Order 23-35,42-48,108-135
ProS 1-15,36-41,58-74,89-100,190-212,219-241,272-295,302-306,366-387,400-417,449-476,482-485,548-561,608-626,654-657,671-710
AlphaFold
Disorder 1-102,133-201,206-206,209-223,232-603,624-710
Order 103-132,202-205,207-208,224-231,604-623
SEG 72-85 ,119-137 ,188-201 ,261-272 ,282-299 ,348-363 ,539-550
Function
Function in SwissProt
Promotes apoptosis of kidney glomerular podocytes. Podocytes are highly specialized cells essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein.
Biological Process
Diagram with PDB data
Ddn/Wwc1Structure of KIBRA and Dendrin Complex
Ddn/Magi2Crystal structure of MAGI2-Dendrin complex