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IID50405
 UniprotQ9QZQ0
ProteinNeuronal PAS domain-containing protein 3
GeneNpas3
OrganismMus musculus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
925
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 56-455 Hetero dimer : IID50373Complex
 Evidence X-RAY 5sy7 B Reference
       Region 5sy7 B 56-58 disorder
       Region 5sy7 B 59-118 order
       Region 5sy7 B 119-147 disorder
       Region 5sy7 B 148-217 order
       Region 5sy7 B 218-263 disorder
       Region 5sy7 B 264-276 order
       Region 5sy7 B 277-286 disorder
       Region 5sy7 B 287-298 order
       Region 5sy7 B 299-313 disorder
       Region 5sy7 B 314-324 order
       Region 5sy7 B 325-335 disorder
       Region 5sy7 B 336-420 order
       Region 5sy7 B 421-428 disorder
       Region 5sy7 B 429-453 order
       Region 5sy7 B 454-455 disorder
 
Prediction
NeProc
Disorder 1-71,123-150,219-258,456-925
Order 72-122,151-218,259-304,313-455
ProS 1-49,63-71,129-133,247-250,258-258,498-503,537-541,553-563,612-617,631-634,651-654,660-665,735-738,753-757,779-791,797-802,814-825,838-856,863-877,887-914
AlphaFold
Disorder 1-50,122-147,218-262,277-286,302-311,325-335,455-925
Order 51-121,148-217,263-276,287-301,312-324,336-454
Pfam Hmmer
PF00989 154-273 4.6e-07
PF08447 348-441 1.5e-20
SEG 234-256 ,417-432 ,461-477 ,524-544 ,598-627 ,696-709 ,739-754 ,759-773
Function
Function in SwissProt
May play a broad role in neurogenesis. May control regulatory pathways relevant to schizophrenia and to psychotic illness.
Biological Process
See also
Diagram with PDB data
Arnt/Epas1/DNACrystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA