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IID90011
 UniprotQ9WYW0
ProteinNAD-dependent protein deacetylase
GenecobB
OrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
246
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 1-246 Hetero dimer : IID50143Complex
 Evidence X-RAY 2h2g A Reference
       Region 2h2g A 1-33 order
       Region 2h2g A 34-42 disorder
       Region 2h2g A 43-245 order
       Region 2h2g A 246-246 disorder
Seq 1-246 Homo octamer :
 Evidence X-RAY 2h2i A Reference
       Region 2h2i A 1-244 order
       Region 2h2i A 245-246 disorder
Seq 1-246 Hetero dimer : P02309
 Evidence X-RAY 2h2h A Reference
       Region 2h2h A 1-33 order
       Region 2h2h A 34-45 disorder
       Region 2h2h A 46-246 order
Seq 1-246 Hetero dimer :
 Evidence X-RAY 3d4b A Reference
       Region 3d4b A 1-33 order
       Region 3d4b A 34-45 disorder
       Region 3d4b A 46-245 order
       Region 3d4b A 246-246 disorder
Seq 1-246 Hetero dimer :
 Evidence X-RAY 3jr3 A Reference
       Region 3jr3 A 1-33 order
       Region 3jr3 A 34-41 disorder
       Region 3jr3 A 42-246 order
Seq 1-246 Hetero dimer :
 Evidence X-RAY 3d81 A Reference
       Region 3d81 A 1-33 order
       Region 3d81 A 34-44 disorder
       Region 3d81 A 45-246 order
Seq 1-246 Hetero tetramer : IID00015Complex
 Evidence X-RAY 2h59 A Reference
       Region 2h59 A 1-246 order
 Evidence X-RAY 2h59 B Reference
       Region 2h59 B 1-246 order
 Evidence X-RAY 4bv2 A Reference
       Region 4bv2 A 1-1 disorder
       Region 4bv2 A 2-33 order
       Region 4bv2 A 34-42 disorder
       Region 4bv2 A 43-245 order
       Region 4bv2 A 246-246 disorder
 Evidence X-RAY 4bv2 B Reference
       Region 4bv2 B 1-2 disorder
       Region 4bv2 B 3-33 order
       Region 4bv2 B 34-44 disorder
       Region 4bv2 B 45-141 order
       Region 4bv2 B 142-144 disorder
       Region 4bv2 B 145-246 order
Seq 1-246 Hetero dimer : IID00015Complex
 Evidence X-RAY 1yc5 A Reference
       Region 1yc5 A 1-33 order
       Region 1yc5 A 34-44 disorder
       Region 1yc5 A 45-245 order
       Region 1yc5 A 246-246 disorder
 Evidence X-RAY 2h2d A Reference
       Region 2h2d A 1-33 order
       Region 2h2d A 34-45 disorder
       Region 2h2d A 46-246 order
 Evidence X-RAY 2h2f A Reference
       Region 2h2f A 1-32 order
       Region 2h2f A 33-44 disorder
       Region 2h2f A 45-246 order
 Evidence X-RAY 2h4f A Reference
       Region 2h4f A 1-36 order
       Region 2h4f A 37-42 disorder
       Region 2h4f A 43-246 order
 Evidence X-RAY 2h4h A Reference
       Region 2h4h A 1-36 order
       Region 2h4h A 37-45 disorder
       Region 2h4h A 46-246 order
 Evidence X-RAY 2h4j A Reference
       Region 2h4j A 1-33 order
       Region 2h4j A 34-43 disorder
       Region 2h4j A 44-246 order
 Evidence X-RAY 3pdh A Reference
       Region 3pdh A 1-33 order
       Region 3pdh A 34-42 disorder
       Region 3pdh A 43-246 order
 Evidence X-RAY 4buz A Reference
       Region 4buz A 1-33 order
       Region 4buz A 34-42 disorder
       Region 4buz A 43-246 order
 
Prediction
NeProc
Order 1-246
AlphaFold
Disorder 1-1,244-244
Order 2-243,245-246
Pfam Hmmer
PF02146 21-195 7.2e-75
Function
Function in SwissProt
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Has also depropionylation activity in vitro. Also able to ADP-ribosylate peptide substrates with Arg or Lys in the +2 position. The role of this function in vivo is not clear.