Search Keyword:


Search option:


IID90017
 UniprotP03404
ProteinProtein Nef
Genenef
OrganismHuman immunodeficiency virus type 1 group M subtype B
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
206
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 2-26
 Evidence NMR 1zec A Reference
       Region 1zec A 2-26 order
       Region 1zec A 2-4 high_rmsd
Seq 2-206 Monomer :
 Evidence X-RAY 3tb8 A Reference
       Region 3tb8 A 2-203 order
       Region 3tb8 A 204-206 disorder
Seqphosphorylation
    6-6 Phosphoserine; by host
 
Prediction
NeProc
Disorder 1-30
Order 31-206
ProS 1-30
AlphaFold
Disorder 1-12,16-16,63-66,69-70,159-160,162-162,205-206
Order 13-15,17-62,67-68,71-158,161-161,163-204
Pfam Hmmer
PF00469 2-205 5.4e-142
SEG 42-56
Function
Function in SwissProt
Extracellular Nef protein targets CD4(+) T-lymphocytes for apoptosis by interacting with CXCR4 surface receptors.