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IID90045
 UniprotP0C1C7
ProteinProtein W
GeneP/V/C
OrganismNipah virus
Sequence LLPS PhaSepDB
PhaSePro
LLPSDB
DrLLPS
 Network xml rdf
Structure
Experiment
  :order   disorder   conflict   PDB cluster   ProS   Pfam Domain   SEG
450
 order/disorder by at least rule
     disorder by at least rule
     order by at least rule
 order/disorder by majority rule
Seq 411-450 Hetero dimer : IID50009Complex
 Evidence X-RAY 6bw0 C Reference
       Region 6bw0 C 411-435 disorder
       Region 6bw0 C 436-443 order
       Region 6bw0 C 444-450 disorder
Seq 411-450 Hetero dimer : IID00749Complex
 Evidence X-RAY 6bvv B Reference
       Region 6bvv B 411-420 disorder
       Region 6bvv B 421-444 order
       Region 6bvv B 445-450 disorder
Seq 441-450 Hetero dimer : IID00301Complex
 Evidence X-RAY 6w0l P Reference
       Region 6w0l P 441-445 disorder
       Region 6w0l P 446-450 order
SeqProS possible 439-443 Nuclear Localization Signal (NLS) Hetero dimer : IID00749Complex
       Region 6bvv B 421-444 order
SeqProS possible 439-443 Nuclear Localization Signal (NLS) Hetero dimer : IID50009Complex
       Region 6bw0 C 436-443 order
SeqProS verified 446-450 Hetero dimer : IID00301Complex
       Region 6w0l P 446-450 order
       Region 6bvv B 445-450 disorder
Seqphosphorylation
    350-350 Phosphoserine; by host
    257-257 Phosphoserine; by host
 
Prediction
NeProc
Disorder 47-160,169-181,191-207,214-232,256-337,352-406,440-450
Order 1-46,161-168,182-190,208-213,233-255,338-351,412-439
ProS 47-59,67-76,83-128,133-160,169-181,191-197,214-232,256-266,273-300,312-318,323-337,352-395,402-406,440-446
Function
Function in SwissProt
Prevent the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta). Interacts with host STAT1 protein in the nucleus, blocking it's phosphorylation by IFN-alpha/beta. Also blocks antiviral state induced by Toll-like receptor 3/TLR3 binding to dsRNA.