20210801 20180803 20180425 20210801 IID00318 Lymphocyte cytosolic protein 2 SH2 domain-containing leukocyte protein of 76 kDa SLP-76 tyrosine phosphoprotein Homo sapiens 533 Q13094 A8KA25 Q53XV4 Involved in T-cell antigen receptor mediated signaling. Cytoplasm. SL-0086 unkown 0 0 Phosphotyrosine 23 23 Phosphoserine 207 207 Phosphoserine 410 410 LCP2 LCP2_HUMAN MALRNVPFRSEVLGWDPDSLADYFKKLNYKDCEKAVKKYHIDGARFLNLTENDIQKFPKLRVPILSKLSQEINKNEERRSIFTRKPQVPRFPEETESHEEDNGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSILPAKPFPNSNSMYIDRPPSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPKIQKPPLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFPLPLPNKPRPPSPAEEENSLNEEWYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDFLSVSDIIDYFRKMPLLLIDGKNRGSRYQCTLTHAAGYP 1 2rorB 122 136 order 2 2 2eapA 1 83 order 1 3 1h3hB 232 241 order 3 4 1ywoP 185 194 order 4 5 232 241 disorder 5 6 2eapA 80 83 high_rmsd 1 1 2eap NMR A.K.GORONCY,M.SATO,N.TOCHIO,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,S.YOKOYAMA SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OF HUMAN LYMPHOCYTE CYTOSOLIC PROTEIN 2 TO BE PUBLISHED nmr 2eap A 1 83 100 0 1 2eap 3555 Monomer monomer 2eapA Q13094 IID00318 2 2ror NMR T.KASAI,M.TANAKA,S.KOSHIBA,T.KIGAWA,S.YOKOYAMA SOLUTION STRUCTURE OF THE VAV1 SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM SLP76 TO BE PUBLISHED nmr 2ror B 122 136 93 0 1 2ror 3889 Hetero dimer 2rorB Q13094 IID00318 2rorA P15498 IID00652 2rorA-2rorB 3 1h3h NMR 12620234 Q.LIU,D.BERRY,P.NASH,T.PAWSON,C.J.MCGLADE,S.S.LI STRUCTURAL BASIS FOR SPECIFIC BINDING OF THE GADS SH3 DOMAIN TO AN RXXK MOTIF-CONTAINING SLP-76 PEPTIDE: A NOVEL MODE OF PEPTIDE RECOGNITION 2003 MOL.CELL 11 471 nmr 1h3h B 232 241 100 0 1 1h3h 3625 Hetero dimer 1h3hA O89100 IID50062 1h3hB Q13094 IID00318 1h3hA-1h3hB 4 1ywo X-RAY 298.0K 7 16061254 L.DENG,C.A.VELIKOVSKY,C.P.SWAMINATHAN,S.CHO,R.A.MARIUZZA STRUCTURAL BASIS FOR RECOGNITION OF THE T CELL ADAPTOR PROTEIN SLP-76 BY THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA1 2005 J.MOL.BIOL. 352 1 x-ray 1ywo P 185 194 100 0 1 1ywo_1 3403 Hetero dimer 1ywoA P10686 1ywoP Q13094 IID00318 1ywoA-1ywoP 5 NMR 12620234 Q.LIU,D.BERRY,P.NASH,T.PAWSON,C.J.MCGLADE,S.S.LI STRUCTURAL BASIS FOR SPECIFIC BINDING OF THE GADS SH3 DOMAIN TO AN RXXK MOTIF-CONTAINING SLP-76 PEPTIDE: A NOVEL MODE OF PEPTIDE RECOGNITION 2003 MOL.CELL 11 471 ProS 1 verified 3 232 241 5 232 241 6-76,145-148,235-235,237-238,418-488,493-531 1-5,77-144,149-234,236-236,239-417,489-492,532-533 4-77,415-533 1-3,78-414 91-133,139-152,158-185,205-278,312-318,327-333,353-356 118-149,177-202,396-411