20210801 20180803 20180425 20210801 IID00320 G protein pathway suppressor 2 Homo sapiens 327 Q13227 B4DXA1 Q6FHM8 (Microbial infection) Required for efficient replication of hepatitis C virus (HCV) by promoting the interaction between VAPA and HCV virus protein NS5A. Cytoplasm, Cytosol. SL-0091 unkown Mitochondrion. SL-0173 unkown Nucleus. SL-0191 unkown 0 0 Asymmetric dimethylarginine 312 312 Asymmetric dimethylarginine; alternate 323 323 Omega-N-methylarginine; alternate 323 323 MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGKSGFAATSQPGPRLPFIQHSQNPRFYHK 1 2l5gA 53 90 order 1 2 2l5gA 53 54 high_rmsd 1 1 2l5g NMR 21240272 J.OBEROI,L.FAIRALL,P.J.WATSON,J.C.YANG,Z.CZIMMERER,T.KAMPMANN,B.T.GOULT,J.A.GREENWOOD,J.T.GOOCH,B.C.KALLENBERGER,L.NAGY,D.NEUHAUS,J.W.SCHWABE 2011 NAT.STRUCT.MOL.BIOL. 18 177 nmr 2l5g A 53 90 100 0 1 2l5g_1 2509 Hetero dimer 2l5gB Q9Y618 IID00109 2l5gA Q13227 IID00320 2l5gB-2l5gA 1-327 949 PF15991 5->292 2.1e-94 G-protein pathway suppressor hmm pfm 6101 PF15991 5->135 5e-30 G-protein pathway suppressor rps pfm 8607 1w1wA 18->115 4e-05 rps scp