SOLUTION STRUCTURE OF THE HETEROTRIMERIC COMPLEX BETWEEN RFX5 AND RFXAP REVEALS MOLECULAR DETAILS ASSOCIATED WITH MHCII GENE EXPRESSION

20210801 20180803 20180328 20210801 IID00425 Regulatory factor X-associated protein RFX DNA-binding complex 36 kDa subunit Homo sapiens 272 O00287 B2R9T8 Q5VZM6 Q8TC40 Part of the RFX complex that binds to the X-box of MHC II promoters. Nucleus. SL-0191 unkown Nuclear localization signal 163 178 0 0 RFXAP RFXAP_HUMAN MEAQGVAEGAGPGAASGVPHPAALAPAAAPTLAPASVAAAASQFTLLVMQPCAGQDEAAAPGGSVGAGKPVRYLCEGAGDGEEEAGEDEADLLDTSDPPGGGESAASLEDLEDEETHSGGEGSSGGARRRGSGGGSMSKTCTYEGCSETTSQVAKQRKPWMCKKHRNKMYKDKYKKKKSDQALNCGGTASTGSAGNVKLEESADNILSIVKQRTGSFGDRPARPTLLEQVLNQKRLSLLRSPEVVQFLQKQQQLLNQQVLEQRQQQFPGTSM 1 2kw3C 214 272 order 1 2 2kw3C 214 223 high_rmsd 1 3 2kw3C 260 272 high_rmsd 1 1 2kw3 NMR K.M.LAIRD,L.L.BRIGGS,J.M.BOSS,M.F.SUMMERS,C.W.GARVIE SOLUTION STRUCTURE OF THE HETEROTRIMERIC COMPLEX BETWEEN RFX5 AND RFXAP REVEALS MOLECULAR DETAILS ASSOCIATED WITH MHCII GENE EXPRESSION TO BE PUBLISHED nmr 2kw3 C 214 272 100 0 1 2kw3_1 2467 Hetero trimer 2kw3C O00287 IID00425 2kw3B P48382 IID00452 2kw3A P48382 IID00452 2kw3C-2kw3B 2kw3C-2kw3A 2kw3B-2kw3A

O14593-1 RFXANK/FRX5 Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK 43-43,46-46,48-51,138-152,155-184,204-204,206-207,222-265 1-42,44-45,47-47,52-137,153-154,185-203,205-205,208-221,266-272 219-254 1-218,255-272 1-8,45-60,69-77,139-152,157-185,196-218,255-258,266-272 18-42,76-91,118-138,163-178,246-266