STRUCTURAL BASIS BY WHICH ALTERNATIVE SPLICING CONFERS SPECIFICITY IN FIBROBLAST GROWTH FACTOR RECEPTORS.

20210801 20180803 20180328 20210801 IID00527 Fibroblast growth factor 10 Keratinocyte growth factor 2 Homo sapiens 208 O15520 C7FDY0 Q6FHR3 Q6FHT6 Q96P59 Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. Secreted. SL-0243 unkown 0 0 0 0 MWKWILTHCASAFPHLPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQGDVRWRKLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRRGQKTRRKNTSAHFLPMVVHS 1 1nunA 64 68 disorder 1 2 1nunA 69 207 order 1 3 1nunA 208 208 disorder 1 1 1nun X-RAY 298K 8.5 12591959 B.K.YEH,M.IGARASHI,A.V.ELISEENKOVA,A.N.PLOTNIKOV,I.SHER,D.RON,S.A.AARONSON,M.MOHAMMADI STRUCTURAL BASIS BY WHICH ALTERNATIVE SPLICING CONFERS SPECIFICITY IN FIBROBLAST GROWTH FACTOR RECEPTORS. 2003 PROC.NATL.ACAD.SCI.USA 100 2266 x-ray 1nun A 64 208 100 2 64 68 208 208 1 1nun_1 2801 Hetero dimer 1nunB P21802 IID00546 1nunA O15520 IID00527 1nunB-1nunA 13-35,69-207 1-12,36-68,208-208 1530 PF00167 78->202 8.7e-53 Fibroblast growth factor hmm pfm 4150 1nunA_ 70->206 3.6e-53 hmm scp 6643 PF00167 78->202 3e-22 Fibroblast growth factor rps pfm 9044 1nunA 69->207 8e-35 rps scp