20210801 20180803 20170927 20210801 IID00635 Ubiquitin-conjugating enzyme E2 Q2 E2 ubiquitin-conjugating enzyme Q2 Ubiquitin carrier protein Q2 Ubiquitin-protein ligase Q2 Homo sapiens 375 Q8WVN8 B7Z3Q2 H3BRG2 Q8N4G6 Q96J08 Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Cytoplasm. SL-0086 unkown 0 0 0 0 MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGSPHSLPPPLTLHCNITESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG 1 1zuoA 197 200 disorder 1 2 1zuoA 201 362 order 1 3 1zuoA 363 363 disorder 1 4 1zuoB 197 200 disorder 1 5 1zuoB 201 340 order 1 6 1zuoB 341 363 disorder 1 1 1zuo X-RAY 298.0K 5.8 22496338 Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANON 2012 MOL CELL PROTEOMICS 11 329 x-ray 1zuo A 197 363 100 2 197 200 363 363 x-ray 1zuo B 197 363 100 2 197 200 341 363 1 1zuo_2 1675 Monomer monomer 1zuoB Q8WVN8 IID00635 2 1zuo_1 1675 Monomer monomer 1zuoA Q8WVN8 IID00635 9-106,201-362 1-8,107-200,363-375 1790 PF00179 269->359 3.2e-13 Ubiquitin-conjugating enzyme hmm pfm 4348 1zuoA1 202->361 7.2e-35 hmm scp 4349 1ukxA_ 9->106 5.5e-10 UBC-like hmm scp 9230 4y1lC1 9->94 3e-04 rps scp 9231 1zuoA1 201->362 2e-60 rps scp