A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASE STRUCTURE-FUNCTION SCREEN.

20210801 20180803 20180228 20210801 IID00638 Ubiquitin-conjugating enzyme E2 U E2 ubiquitin-conjugating enzyme U Ubiquitin carrier protein U Ubiquitin-protein ligase U Homo sapiens 321 Q5VVX9 Q8N1D4 Catalyzes the covalent attachment of ubiquitin to other proteins. 0 0 0 0 MHGRAYLLLHRDFCDLKENNYKGITAKPVSEDMMEWEVEIEGLQNSVWQGLVFQLTIHFTSEYNYAPPVVKFITIPFHPNVDPHTGQPCIDFLDNPEKWNTNYTLSSILLALQVMLSNPVLENPVNLEAARILVKDESLYRTILRLFNRPLQMKDDSQELPKDPRKCIRPIKTTSFSDYYQTWSRIATSKATEYYRTPLLKVPNFIGQYYKWKKMDLQHQKEWNLKYSVIKCWLARKRMPHEVTHSMEEIKLCPTLIPTTDEIFLESPTAINSITDIYETEEEGWKSDTSLYENDTDEPREEEVEDLISWTNTLNTNTSED 1 1yrvA 1 148 order 1 2 1yrvA 149 150 disorder 1 1 1yrv X-RAY 298.0K 7 22496338 Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANON A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASE STRUCTURE-FUNCTION SCREEN. 2012 MOL CELL PROTEOMICS 11 329 x-ray 1yrv A 1 150 100 1 149 150 1 1yrv_1 3399 Monomer monomer 1yrvA Q5VVX9 IID00638 1-148 149-199,235-321 200-234 1795 PF00179 9->144 2.8e-37 Ubiquitin-conjugating enzyme hmm pfm 4354 1yrvA1 1->146 2.4e-42 hmm scp 9235 1yrvA1 1->147 9e-55 rps scp