20210801 20180803 20180328 20210801 IID50028 Ubiquitin fusion degradation protein 1 Polymerase-interacting protein 3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 361 P53044 D6VUI5 Q45U36 Functions at a post-ubiquitation step in the ubiquitin fusion degradation (UFD) pathway. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway. Required for the proteasome-dependent processing/activation of MGA2 and SPT23 transcription factors leading to the subsequent expression of OLE1. Has an additional role in the turnover of OLE1 where it targets ubiquitinated OLE1 and other proteins to the ERAD. Cytoplasm. SL-0086 unkown Phosphoserine 354 354 MFSGFSSFGGGNGFVNMPQTFEEFFRCYPIAMMNDRIRKDDANFGGKIFLPPSALSKLSMLNIRYPMLFKLTANETGRVTHGGVLEFIAEEGRVYLPQWMMETLGIQPGSLLQISSTDVPLGQFVKLEPQSVDFLDISDPKAVLENVLRNFSTLTVDDVIEISYNGKTFKIKILEVKPESSSKSICVIETDLVTDFAPPVGYVEPDYKALKAQQDKEKKNSFGKGQVLDPSVLGQGSMSTRIDYAGIANSSRNKLSKFVGQGQNISGKAPKAEPKQDIKDMKITFDGEPAKLDLPEGQLFFGFPMVLPKEDEESAAGSKSSEQNFQGQGISLRKSNKRKTKSDHDSSKSKAPKSPEVIEID 1 1zc1A 1 208 order 1 2 1zc1A 1 15 high_rmsd 1 3 1zc1A 201 208 high_rmsd 1 1 1zc1 NMR 16004872 S.PARK,R.ISAACSON,H.T.KIM,P.A.SILVER,G.WAGNER 2005 STRUCTURE 13 995 nmr 1zc1 A 1 208 100 0 1 1zc1 4005 Monomer monomer 1zc1A P53044 IID50028 15-208 1-14,209-361 2184 PF03152 21->199 1.1e-74 Ubiquitin fusion degradation protein UFD1 hmm pfm 7200 PF03152 21->199 2e-48 Ubiquitin fusion degradation protein UFD1 rps pfm