STRUCTURAL BASIS OF THE INTERACTION BETWEEN P- ELEMENT SOMATIC INHIBITOR AND U1-70K ESSENTIAL FOR THE ALTERNATIVE SPLICING OF P-ELEMENT TRANSPOSASE.

20210801 20180803 20180328 20210801 IID50033 U1 small nuclear ribonucleoprotein 70 kDa Drosophila melanogaster 448 P17133 Q564D5 Q9VM56 Mediates the splicing of pre-mRNA by binding to the stem loop I region of U1-snRNA (PubMed:15611175). Required during oogenesis for nurse cell chromatin dispersal (PubMed:24244416). Chromosome. SL-0468 unkown Nucleus. SL-0191 unkown 0 0 0 0 snRNP-U1-70K RU17_DROME MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDREREKKKKRSKSRERESSRERRERKRERRDRERGTGSGGDVKERKPDFRDMDVIKIKEEPVDDGYPTFDYQNATIKREIDDEDEEKYRPPPAHHNMFSVPPPPILGRGNASTNPNPDNGQQSSGDPSWWRQ 1 2bn5B 405 425 order 1 2 2bn5B 405 412 high_rmsd 1 3 2bn5B 424 425 high_rmsd 1 1 2bn5 NMR 15990112 T.IGNJATOVIC,J.-C.YANG,J.BUTLER,D.NEUHAUS,K.NAGAI STRUCTURAL BASIS OF THE INTERACTION BETWEEN P- ELEMENT SOMATIC INHIBITOR AND U1-70K ESSENTIAL FOR THE ALTERNATIVE SPLICING OF P-ELEMENT TRANSPOSASE. 2005 J.MOL.BIOL. 351 52 nmr 2bn5 B 405 425 100 0 1 2bn5 3485 Hetero dimer 2bn5A Q7JPS0 2bn5B P17133 IID50033 2bn5A-2bn5B 2-202,206-206,221-221,223-227,315-349,419-419 1-1,203-205,207-220,222-222,228-314,350-418,420-448 1-69,74-187,318-345 70-73,188-317,346-448 70-73,188-219,230-236,272-280,349-356,364-395,401-437,443-448 60-75,185-202,211-239,248-350,397-402