20210801 20180803 20180425 20210801 IID50076 Transposable element Tc3 transposase Caenorhabditis elegans 329 P34257 Binds specifically to the terminal nucleotides of the TC3 inverted repeat. Its expression results in frequent excision and transposition of endogenous TC3 elements. TC3 transposase acts by making double strand breaks at the ends of TC3 element. The excised element would then be inserted into a target sequence. Nucleus membrane. SL-0182 unkown Nucleus, Nuclear pore complex. SL-0185 unkown 0 0 0 0 MPRGSALSDTERAQLDVMKLLNVSLHEMSRKISRSRHCIREYLKDPVSYGTSKRAPRRKALSVRDERNVIRAASNSCKTARDIRNELQLSASKRTILNVIKRSGVIVRQKLRPAPLLSADHKLKRLEFAKNNMGTNWSKVVFSDEKKFNLDGPDGCRYYWRDLRKEPMVFSRRNFGGGTVMVWGAFTEKKKLEIQFVSSKMNSTDYQNVLELELSKYLRHYSRKDFRFQQDNATIHVSNSTRDYFKLKKINLLDWPARSPDLNPIENLWGILVRIVYAQNKTYPTVASLKQGILDAWKSIPDNQLKSLVRSMEDRLIEIIRTQGNPINY 1 1tc3C 2 52 order 1 2 1u78A 1 1 disorder 2 3 1u78A 2 104 order 2 4 1u78A 105 135 disorder 2 1 1tc3 X-RAY 5.5 9312061 G.VAN POUDEROYEN,R.F.KETTING,A.PERRAKIS,R.H.PLASTERK,T.K.SIXMA 1997 EMBO J. 16 6044 x-ray 1tc3 C 2 52 98 0 1 1tc3_1 3089 Monomer monomer 1tc3C P34257 IID50076 2 1u78 X-RAY 293K 5.5 15304566 S.WATKINS,G.VAN POUDEROYEN,T.K.SIXMA 2004 NUCLEIC ACIDS RES. 32 4306 x-ray 1u78 A 1 135 99 2 1 1 105 135 1 1u78_1 3122 Monomer monomer 1u78A P34257 IID50076 2-104 1-1 105-329 2283 PF11427 3->52 1.7e-35 Tc3 transposase hmm pfm 2284 PF13358 140->289 2.4e-22 DDE superfamily endonuclease hmm pfm 2285 PF01498 75->133 6e-11 Transposase hmm pfm 4713 1u78A2 55->104 4e-25 hmm scp 4714 1tc3C_ 2->51 3.2e-23 hmm scp 7296 PF11427 3->51 1e-13 Tc3 transposase rps pfm 7297 PF01498 67->133 9e-06 Transposase rps pfm 7298 PF13358 140->289 2e-09 DDE superfamily endonuclease rps pfm 9570 1tc3C 2->52 8e-16 rps scp 9571 1u78A2 55->104 1e-11 rps scp