20210801 20180803 20180228 20210801 IID50078 Ubiquitin-conjugating enzyme E2 G2 E2 ubiquitin-conjugating enzyme G2 Ubiquitin carrier protein G2 Ubiquitin-protein ligase G2 Mus musculus 165 P60605 P56554 Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation. Nucleus. SL-0191 unkown 0 0 N-acetylalanine 2 2 Ube2g2 UB2G2_MOUSE MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL 3 3fshA 1 95 order 1 4 3fshA 96 107 disorder 1 5 3fshA 108 165 order 1 6 3fshB 1 95 order 1 7 3fshB 96 107 disorder 1 8 3fshB 108 165 order 1 1 3fsh X-RAY 293K 7.7 19223579 W.LI,D.TU,L.LI,T.WOLLERT,R.GHIRLANDO,A.T.BRUNGER,Y.YE 2009 PROC.NATL.ACAD.SCI.USA 106 3722 x-ray 3fsh A 1 165 100 0 x-ray 3fsh B 1 165 100 0 1 3fsh 3594 Hetero trimer 3fshC Q9UKV5 IID00226 3fshB P60605 IID50078 3fshA P60605 IID50078 3fshC-3fshB 3fshB-3fshA 3-165 1-2 6-165 1-5